Curriculum Vitae. Amber J. Hackstadt. Office Address: Education: Academic Appointments:

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1 Amber J. Hackstadt Office Address: Curriculum Vitae Vanderbilt University School of Medicine Department of Biostatistics 2525 West End, Suite Nashville, TN Education: Southeast Missouri State University, Cape Girardeau, MO B.S. in Mathematics and Secondary Education, 2003 Summa Cum Laude Masters of Natural Science in Mathematics, 2005 Thesis: Behrens-Fisher Problem for Bivariate Dichotomous Data M.S. in Statistics, 2008 PhD in Statistics, 2011 Dissertation: Bayesian Shape-restricted Regressions Splines Johns Hopkins University, Baltimore, MD Postdoctoral Fellowship, 2014 Department of Biostatistics Academic Appointments: Research Assistant Professor, Department of Biostatistics, Vanderbilt University School of Medicine Nashville, TN, 2015-Present

2 Other Employment: Instructor: Southeast Missouri State University, Cape Girardeau, MO, Adjunct Instructor: Three Rivers Community College, Poplar Bluff, MO, Fall 2004 Instructor/Online Course Coordinator/Teaching Assistant: Department of Statistics,, Research Assistantship: Center for Bioinformatics, Colorado State University, Fort Collins, CO, Biometric Internship: U.S. Fish and Wildlife Service, Anchorage, Alaska, Summer 2008 Research Assistantship: Department of Statistics, Colorado State University, Fort Collins, CO, 2010 Statistical Consultant: Franklin A. Graybill Statistical Laboratory, Department of Statistics,, 2011 Biostatistician: Social & Scientific Systems, Inc. Durham, NC, Professional Organizations: American Statistical Association International Biometric Society Professional Activities: Intramural Member of Graduate Program Committee, 2016-present Department of Biostatistics, Vanderbilt University Member of Admissions Committee, 2017-Present Department of Biostatistics, Vanderbilt University

3 Extramural Have reviewed papers for the following journals: Biostatistics American Journal of Epidemiology BMC Bioinformatics Environment International Communications in Statistics Theory and Methods. Academic Awards: Homer Roscoe and Carrie Findley Bolon Scholarship, Southeast Missouri State University, Cape Girardeau, MO, 2002 B. F. and Carrie Woodburn Johnson Scholarship, Southeast Missouri State University, Cape Girardeau, MO, 2003 George A. Penzel Family Scholarship, Southeast Missouri State University, Cape Girardeau, MO, 2003 Russel and Elnora Michel Mathematics Scholarship, Southeast Missouri State University, Cape Girardeau, MO, 2003 Cecil Elsie Gross Education Scholarship, Southeast Missouri State University, Cape Girardeau, MO, 2003 Elmer Remmenga Scholarship in Applied Statistics, Colorado State University, Fort Collins, CO, 2007 Student Poster Competition Winner, Graybill Conference, Colorado State University, Fort Collins, CO, 2011 Teaching Activities: Extramural Courses Intermediate Algebra (MA095), Instructor, Southeast Missouri State University, Cape Girardeau, MO

4 Intermediate Algebra (MATH 153), Instructor, Fall 2004 Three Rivers Community College, Poplar Bluff, MO Statistics for Business Students (STAT 204), Teaching Assistant, 2005 Introduction to Biostatistics (STAT 307), Instructor, Experimental Design (STAT650), Online Course Coordinator, 2009 Multivariate Statistics (STAT460/STAT560), Online Course Coordinator, 2010 Bayesian Statistics (STAT 675K), Guest Lecturer, 2010 Internal Seminars, Lectures, and Workshops A Brief Introduction to Environmental Biostatistics. Health Services Research Work in Progress Seminar, Vanderbilt University Medical Center, January 24, 2017 An Introduction to Propensity Score Methods. Clinical Research Center Research Skills Workshop, Vanderbilt University Medical Center, October 6, 2017 Research Program: 2I01CX Roumie (PI) 10/01/ /30/2020 Effectiveness of Hypoglycemic Medications Among Veterans with CKD Role: Co-Investigator P30 DK Elasy (PI) 09/19/ /30/2021 Vanderbilt Center for Diabetes Translation Research Role: Biostatistician P30DK20593 Powers (PI) 01/12/ /31/2022 Diabetes Research and Training Center Role: Biostatistician

5 VUMC57172 Hackstadt (Subrecipient PI) 11/01/ /31/2016 Statistical Methods for Complex Environmental Health Data Role: Subrecipeint PI VA Merit Roumie (PI) 10/01/ /30/2016 Effectiveness of Second Line Hypoglycemic Medications Among Veterans Role: Co-Investigator HHS A Griffin (PI) 08/01/15-11/01/2015 Comparative Effectiveness DEcIDE-2 Consortia Task Order 2 Role: Key personnel R01 ES Peng (PI) 10/01/ /31/2013 Statistical methods for complex environmental health data Role: Trainee Publications and Presentations: Articles in Refereed Journals Amber J. Hackstadt and Ann M. Hess (2009). Filtering for Increased Power for Microarray DataAnalysis, BMC Bioinformatics 10(11). Mary C. Meyer, Amber J. Hackstadt, and Jennifer A. Hoeting (2011). Bayesian Estimation and Inference for Generalised Partial Linear Models Using Shape-Restricted Splines. Journal of Nonparametric Statistics 23(4) Amber J. Hackstadt and Roger D. Peng (2014). A Bayesian Multivariate Receptor Model for Estimating Source Contributions to Particulate Matter Pollution using National Databases. Environmetrics 25(7) Amber J. Hackstadt, Elizabeth C. Matsui, D'Ann L. Williams, Gregory B. Diette, Patrick N. Breysse, Arlene M. Butz, and Roger D. Peng (2014). Inference for Environmental Intervention Studies using Principal Stratification. Statistics in Medicine 33(28) Roger D. Peng, Arlene M. Butz, Amber J. Hackstadt, D'Ann L. Williams, Gregory B. Diette, Patrick N. Breysse, and Elizabeth C. Matsui (2015). Estimating the Health Benefit of Reducing Indoor Air Pollution in a Randomized Environmental Intervention. Journal of Royal Statistical Society-Series A 178(2)

6 Jenna Krall, Amber J. Hackstadt and Roger D. Peng (2017). A hierarchical modeling approach to estimate regional acute health effects of particulate matter sources Statistics in Medicine 36(9) Christianne L.Roumie, Jea Young Min, Lucy D Agostino McGowan, Caroline Presley, Carlos G. Grijalva, Amber J. Hackstadt, Adriana M. Hung, Robert A. Greevy, Tom Elasy, and Marie R. Griffin (2017). Comparative safety of sulfonylurea and metformin monotherapy on the risk of heart failure: a cohort study. Journal of the American Heart Association. 6(4). Presentations: Invited Shape-Restricted Fixed and Free-knot Regression Splines. Biostatistics and Informatics Department, University of Colorado Denver, Denver, CO. April 27, Estimating the health benefit of reducing indoor air pollution in a randomized environmental intervention using principal stratification. Royal Statistical Society 2016 Conference, Manchester, England. September 8, Statistical methods to estimate exposures to multiple pollutants. Western North American Region of the International Biometric Society Annual Meeting, Santa Fe, NM, June 25, Contributed Amber J. Hackstadt and Ann M. Hess. Microarray Analysis: P-values, Filtering, and Multiple Testing Adjustments. Conference on Applied Statistics in Agriculture, Manhattan, Kansas, Amber J. Hackstadt. A Bayesian Approach to Fitting Mixed Models using Shape- Restricted Regression Splines. ASA CO/WY Spring Meeting, Boulder, CO, Amber Hackstadt, Mary C. Meyer and Jennifer A. Hoeting. A Bayesian Approach to Mixed Models using Shape-Restricted Regression Splines. Joint Statistical Meetings; Vancouver, British Columbia, Amber Hackstadt, Mary C. Meyer and Jennifer A. Hoeting. Changepoint Analysis using Shape-Restricted Regression Splines in a Bayesian Framework. Joint Statistical Meetings, Miami, Florida, 2011.

7 Amber J. Hackstadt and Roger D Peng. Examining the Effectiveness of a Pollution- Targeted Environmental Intervention on Improving Health. Joint Statistical Meetings, Montréal, Canada, Posters Amber Hackstadt, Mary C. Meyer and Jennifer A. Hoeting. Bayesian Shape-Restricted Spline Model Including Changepoints. Graybill Conference, Fort Collins, CO, Amber J. Hackstadt and Roger D. Peng. A Bayesian Source Apportionment Model for PM Monitoring Data. International Society for Environmental Epidemiology Conference, Columbia, SC Amber J. Hackstadt. Inference for Environmental Intervention Studies using Principal Stratification. Women in Statistics Conference, Cary, NC, Amber J. Hackstadt and Roger D. Peng. Estimating Source-Specific Effects of Fine Particulate Matter Emissions on Cardiovascular and Respiratory Hospitalizations using SPECIATE and NEI Data. ENAR Spring 2013 Meeting, Orlando, FL, 2013.