Building for the Future: Toxicology Training Centers

Building for the Future: Toxicology Training Centers

Building for the Future: Toxicology Training Centers 1821 Michael Faraday Drive Suite 300 Reston, VA 20190 Tel: 703.438.3115 Fax: 703.438.3113 E-mail: sothq@toxicology.org Web Site: www.toxicology.org Notice of Rights All text and graphics are 2011 by the unless noted. All rights reserved. Published 2011. The graphics images of the Mountain Ash that are shown throughout the book were selected because this species is symbolic of mastership and power. The Ash grows throughout the world and lives for hundreds of years. The brightly colored berries that adorn the tree have medicinal qualities and essential oils derived from ash are said to enhance a sense of strength and flexibility. Like the Mountain Ash, the Society has longevity and strength in its membership. The complex, multi-layered ash tree represents the strength of our membership as we combine our efforts to be one entity nourishing many species with our knowledge. This publication has been produced electronically by the. The author(s) of each article appearing in this publication is/are solely responsible for the content, photographs and/or images thereof; the publication of an article shall not constitute or be deemed to constitute any representation or liability by the.

CONTENTS History of the Toxicology Training Program at the University of Arizona...1 A Short History of Toxicology Training at the University Arkansas for Medical Sciences...3 Toxicology at Boston University School of Public Health, Department Environmental Health...4 History of the NIEHS T32 Training Program in Environmental Pathology at Brown University...6 University at Buffalo, Department of Pharmacology and Toxicology...9 Training in Toxicology: Egyptian Vision...11 Toxicology Training at University of California, Berkeley...21 Environmental Toxicology at the University of California, Davis...25 UCLA Molecular Toxicology Doctoral Program...26 Toxicology Training Program in Japan...31 The University of Chicago and the Tox Lab...36 Environmental Health and Toxicology at the University of Cincinnati: An Interdisciplinary Approach...38 Clemson University Graduate Program in Environmental Toxicology History of the Program...44 Toxicology Training: Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University...45 Toxicology at the University of Connecticut...47 The Department of Pharmacology and Toxicology at East Carolina University, Greenville, North Carolina...53 University of Florida Center for Environmental & Human Toxicology...55 Toxicology Training Activities at Howard University...56 Toxicology Program at Indiana University...57 Toxicology at the University of Iowa...58 Interdepartmental Toxicology Graduate Program a Iowa State University...63 A Rich History of Toxicology Research and Training at the University of Kansas Medical Center...66 Toxicology Training at Karolinska Institutet...69 Toxicology History at Louisiana State University Health Sciences Center in Shreveport...72 Toxicology Milestones at the Department of Pharmacology and Toxicology, University of Louisville...75

The Lovelace Organization and 50 Years of Progress in Inhalation Toxicology...79 University of Maryland System Wide Program in Toxicology...86 History of Toxicology Research and Training at the Massachusetts Institute of Technology...89 University of Michigan...95 Michigan State University Multidisciplinary Graduate Program in Environmental and Integrative Toxicological Sciences...96 University of Minnesota Toxicology Graduate Program...98 The University of Nebraska Center for Environmental Health and Toxicology...99 Curriculum in Toxicology, University of North Carolina at Chapel Hill...100 Toxicology at North Carolina State University...101 The Toxicology Program at Oregon State University... 103 Environmental Health Sciences Training at the University of Pennsylvania...107 Training Program and Grants at the University of Pittsburgh...109 Toxicology Training Centers Purdue University...110 Toxicology at the University of Rochester: From the Manhattan Project to the Environmental Basis of Human Diseases... 111 San Diego State University... 119 Toxicology Training Center at the School of Pharmaceutical Sciences University of São Paulo, São Paulo, Brasil... 121 History of the Baccalaureate Toxicology Program at St. John s University, College of Pharmacy & Allied Health Professions...122 History of the Toxicology Training Program at The University of Texas at Austin and the University of Texas MD Anderson Cancer Center-Science Park Research Division...124 Toxicology on the Border: University of Texas at El Paso s Toxicology Program...129 Toxicologists Training Center Texas Tech University...131 Forty Years of Toxicology at the University of Utah... 134 MeHarry Medical College-Vanderbilt University Advanced Research Cooperation in Environmental Health (ARCH) Consortium...135 Toxicology Training at the University of Washington, 1979 to Present...137 Wayne State University...141 Toxicology at West Virginia University...144 The Molecular and Environmental Toxicology Center and Graduate Program at the University of Wisconsin-Madison...145 iv 50 th Anniversary Book

H Toxicology Training Centers istory of the Baccalaureate Toxicology Program at St. John s University, College of Pharmacy & Allied Health Professions by Sue M. Ford, Ph.D., DABT, Louis D. Trombetta, Ph.D.; and John-Emery Konecsni In the late sixties, Dr. Vincent de Paul Lynch applied for and received a five-year grant from the Department of Health, Education, and Welfare to establish a baccalaureate program in toxicology in the College of Pharmacy at St. John s. An Advisory Panel was assembled in the spring of 1968, comprised of the dean of the college, faculty from the university, a toxicologist from a private analytical laboratory, the commissioner of the NYC Department of Air Pollution Control, the chief toxicologist from the Suffolk County Medical Examiner s Office, the director of Haskell Laboratories (Delaware), and the science editor from WCBS-TV, New York. Thus, the curriculum was developed by the faculty of the college with the advisement of individuals from diverse areas of toxicology including industry, forensics, environment, and government. St. John s University Dinner, SOT meeting 2009 In the application filed with the New York State Education Department, Dr. Lynch cited the 1959 Dubois and Geiling Textbook of Toxicology and a talk by Dr. R. Baker (NIH) at the 1968 SOT meeting as indicating the need for trained toxicologists. Drawing on observations from the local New York City environment, Dr. Lynch wrote that a bachelor level degree in toxicology would provide toxicology employers with employees having valuable training in chemistry, biology, pharmacology, as well as toxicology. In addition, he stated that students with this degree will possess the attributes and prerequisites for a truly graduate education in toxicology. The toxicology major was approved by New York State Department of Education in September 1969. The initial faculty consisted of two senior pharmacologists (with Dr. Lynch as the program director), an additional faculty hired with 100 percent toxicology teaching responsibility, and an adjunct forensic toxicologist (who later became a full-time faculty member). The first progress report filed with the state in May 1972 showed a total of 23 enrolled students: one senior, six juniors, ten sophomores, and six freshmen. By this time, the students had already formed a toxicology club (now named Tau Omega Chi) and had requested representation on the above-mentioned Advisory Panel and the college s faculty council. From the start, the major was designed as a four-year science-intensive degree. Now as then students in the first two years take basic university core courses and the major pre-requisites (math, statistics, chemistry, biology, physics, anatomy & physiology, with the respective laboratories). The initial focus of the program was in forensic and clinical toxicology and has evolved to include all areas of modern toxicology: environmental, biochemical, molecular, analytical, occupational, and risk analysis. Students are introduced to their major in the sophomore year with a course entitled Current Issues in Toxicology. In the junior and senior years they take biochemistry with lab, principles of toxicology, pharmacology, pharmacologic toxicology with lab, analytical & quantitative toxicology with lab and regulatory toxicology & risk analysis. For the later course, seniors complete a capstone project analyzing a hypothetical chemical disaster in their last 122 Building for the Future

History of the Baccalaureate Toxicology Program at St. John s University, College of Pharmacy & Allied Health Professions semester, which they present to the college at the end of spring semester. Despite its rigor, the major is not a one-note science degree inasmuch as the students also take humanities, social sciences, and language requirements. St. John s University Students and Faculty at the MASOT meeting, Spring 2006 The academic environment at St. John s has allowed the program to flourish. The program profits from being part of a large university (20,00 students) with academic, service, and research resources to support our mission to train students in science and toxicology. In 2004, the University designated the Toxicology Program as a Program of Distinction. There is a vibrant graduate science community at St. John s including toxicology which provides a model pathway to graduate school for the undergraduates. Being housed in the College of Pharmacy & Allied Health Professions envelops students in an environment dedicated to studying and solving contemporary health problems. Recently the university has developed a global initiative providing students with opportunities to study abroad. Toxicology students have always been encouraged to become involved in research (allowing for six elective credits of research) and extracurricular activities. Many participate in research in faculty laboratories; exceptional students can enroll in the B.S./M.S. option, which was an early feature of the program. There is significant interaction with toxicology graduate students. Tau Omega Chi invites monthly speakers drawn from faculty and graduate students, sponsors the ever-popular toxicology bake sale to raise funds, and also co-sponsors toxicology freshman orientation. The culmination of the academic year is the annual Toxicology Exposition which had its genesis in an undergraduate toxicology poster session in 1995. It has since grown into a day-long event featuring a distinguished toxicologist as the keynote speaker, student posters, career information, presentation of the seniors capstone project, graduation awards, and the Tox Throwdown game show. Many local alumni attend the event and keep track of the program through its Web site. For several years faculty accompanied students to an annual student conference in West Virginia. More recently, our graduate and undergraduate students have benefitted from participating in MASOT. MASOT generously supports students from the toxicology programs in its region by providing transportation funds, student career workshops during the meetings, student poster sessions, and the gracious interaction of members with the students. Students completing the program proceed into various career paths. Many pursue higher education, including graduate school in various disciplines such as toxicology, public health, or biomedical programs., Up to half of the students are pre-medical or pre-dental. We are fortunate in being located in a large urban area including New York City and points north, Long Island, New Jersey, and Connecticut. The many academic institutions, government agencies, and science-related industries in the tri-state region provide a wide range of employment positions for our graduates. The toxicology program at St. John s celebrated its 40th Anniversary in 2009. Currently we have 60 students enrolled in the program and ten full-time toxicology faculty who also teach in the graduate and pharmacy programs. There are 25 other scientists (medicinal chemistry, pharmacology, pharmaceutics) in the Pharmaceutical Sciences department who contribute to the education of our students. Our program continues strong to this day, providing students with small toxicology classes taught by graduate faculty who have embraced the challenges and rewards of educating undergraduates. 123 Building for the Future