Research as a Career: A Perspective From Young Scientists

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Research as a Career: A Perspective From Young Scientists Dr. Pradeep Kumar Dabla MD, PGDHA, PGDBA NABL Assessor ISO 15189:2012 Chair, IFCC Task Force for Young Scientists (TFYS)

IFCC Task Force for Young Scientists (TF-YS) TF-YS International Federation of Clinical Chemistry & Laboratory Medicine (IFCC)has assembled Task Force Young Scientists (TF-YS) in 2010 Chair: Dr. Pradeep K. Dabla AIM Medical/Science graduate- <40 years of age To involve YS- with IFCC & Laboratory Medicine To face ongoing changes OBJECTIVES To identify Networking Training Participation Multidisciplinary exchanges- different fields & different ideas

It is understood as systematic, controlled, empiric and critical investigation of hypothetic statements on supposed relationships among phenomenon. It is a process in which thinking is dominant. Carl Sagan (exobiologist looking for extraterestrial life) Research Science is composed of agregated facts from which one can create general laws and Conclusions. Charles Darwin 3

Phases of research process Conducting research comprises a series of logical sequential steps: planning, searching, discovery, reflection, synthesis, revision, and learning. 4

Outline Career options for budding medical biochemists Why choose a research career? Rewards & challenges What does it take to be a researcher? Opportunities in India Opportunities in abroad Final word 5

What is Clinical Biochemistry? Diagnostic Medicine: Patient Care Teaching / Academics Medical Students Residents Graduate / Postgraduate Students Fellow Physicians Basic and Clinical Research 6

What else? Why you chosen science? Where is the current market trend and where we fit in those science industries? What are your best competitive skills? What are your most important career considerations? 7

Career Paths Academia Government, Research Institutes, Non-Profits Industry CEO Tenured Professor Dean Director or Other VP Tenure track Educator Scientist or Other Director Manager Fellow or Principal Scientist Track Science and Business Postdoc Copyright 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 8

Faculty Member in Medical Institute Most commonly opted Noble profession Exciting and challenging Satisfaction of moulding Good salaries Get chance for lab practice & research 9

Faculty Member in Medical Institute the other side of the coin Long working hours Promotions? Status of demand and supply Choice of institute / place Fierce competition Exploitation in Private Institutes No. Medical colleges 381 With MD Biochemistry 201 MD Biochem seats 497 Faculty in Biochemistry 3225 Source: Medical Council of India 10

Why Choose a Research Career? Rewarding and exciting Work on bigger problem The exhilaration of putting a story together Expert in your field Standing out from the crowd Teaching academic environment Travel Prestige/honor/fame 11

Is there a downside? Perception of peers Use it or loose it - clinical Skills Financial rewards Low in the beginning Uncertainty in promotions Roller-coaster ride Publish or perish Funding 12

Research skills Hard work, intelligence & desire. also good luck Target early success - a high impact paper as a MD or PhD student / junior postdoc is boon Take time to define in detail the research question Clear direction with proper order & timings Pause for thought Leading / contributing to several projects Raising research profile (meetings, networking, social media ) 13

Scope for Research Career in India PGs in Biochem Posts in Res Labs Ad hoc Posts in Research projects Posts in reputed medical institutes Pharma ceutical / biotech industries Active involvement in Research; high impact publications; papers in conferences; network-network-network 14

Opportunities in India: Funding agencies & relevant schemes Department of Health Research (DHR) Establishment of Multi- Disciplinary Research Units in GMCs and Govt. Research Institutes 80 units in 2013-15; 503.85 cr (INR). Budget Indian Council of Medical Research Research Associate-ships Postdoctoral fellowships Posts in ad hoc Research Projects 15

Department of Biotechnology Several autonomous institutes R & D projects Human genetics & genome analysis Bioinformatics Opportunities in India: Funding agencies & relevant schemes Department of Science and Technology Extra Mural Research Funding (Individual Centric) Biochemistry, Molecular Biology & Microbiology Health Sciences Start-Up Research Grant (Young Scientists) project grant + fellowship; eligibility: PhD/ MD/MS 16

Opportunities in India: Funding agencies & relevant schemes Council of Scientific & Industrial Research CSIR Research Associateships (RA) Senior Research Associateships (Scientists pool) in in the area of healthcare, drugs & pharmaceuticals for MD/MS/MDS University Grants Commission Research Awards for faculty UGC - Faculty research promotion schemes (FRPS) 17

Opportunities in Abroad Substantial benefit of academic research New expertise & critical input Foster long-term collaborations Financial rewards Important factor for academic progression 18

Scope for research career in abroad PGs in Biochem Active research, high impact Papers & presentations, sound training & competency in techniques during PG Ad hoc posts in research projects, labs or institutes; experience & publications Doctoral programmes Post-doctoral fellowships Faculty positions Clinical Lab consultants Positions in res industry 19

CAREER NIH Offers Funding Programs to Support Scientists at Every Stage of Their Career Approx. Stage of Research Training and Development Mechanism of Support GRADUATE/ MEDICAL STUDENT POST DOCTORAL Predoctoral Institutional Training Grant (T32) Predoctoral Individual NRSA (F31) Predoctoral Individual MD/PhD NRSA (F30) Postdoctoral Institutional Training Grant (T32) Postdoctoral Individual NRSA (F32) NIH Pathway to Independence (PI) Award (K99/R00) EARLY Mentored Research Scientist Development Award (K01) Mentored Clinical Scientist Development Award (K08) Mentored Patient-Oriented RCDA (K23) Mentored Quantitative RCDA (K25) Small Grant (R03) Research Project Grant (R01) Exploratory/Development Grant (R21) MIDDLE Independent Scientist Award (K02) Midcareer Investigator Award in Patient-Oriented Research (K24) SENIOR Senior Scientist Award (K05) *Graph represents a small sample of NIH funding mechanisms available. Slide borrowed from Michael A Sesma PhD (NIH) ppt 20

Now what? Dr Pradeep Kumar Dabla 25 Nov 21 2015

Identify the Career Path You Want & Find Positions That Fit You Do your research Internet job sites Professional and trade organization websites Biotech industry news Career Opportunities in Biotechnology Toby Freedman Get up-to-date training Cross-functional training Navigating a Career Change in Biotechnology Network Professional organization meetings Local community and friends Informational interviews Find ways to volunteer Professional organizations Academic institutions Other nonprofits 22

The Future of the Life Sciences Remains Promising Significant unmet medical needs remain Neurological disorders Cancer Infectious diseases Diabetes Obesity Cardiovascular diseases Aging population Tremendous market opportunity in China and India Energy Copyright 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 23 23

TF-YS Dream is not what you see in sleep. It is the thing which does not let you sleep Dr APJ Abdul Kalam Former President of India Health Research needs you Thank you Dr. Pradeep Kumar Dabla MD, PGDHA, PGDBA Chair, IFCC Task Force for Young Scientists (TFYS)