ANTITHROMBOTIC THERAPY SYMPOSIUM. Improving Anticoagulation in Detroit. Friday, April 28, :30 am 4:30 pm. The Dearborn Inn Dearborn, Michigan

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18th Annual ANTITHROMBOTIC THERAPY SYMPOSIUM Improving Anticoagulation in Detroit Friday, April 28, 2017 7:30 am 4:30 pm The Dearborn Inn Dearborn, Michigan sponsored by In collaboration with

Program Overview A panel of national and international experts will present the most recent, cutting edge information on different topics regarding antithrombotic therapy. The focus will be on advanced knowledge in basic sciences, clinical advances, controversies, and clinical pearls and application of antithrombotic therapy. Space is limited so early registration is encouraged. Target Audience Physicians in Primary Care, Internal Medicine, Family Practice, Hematology, Pulmonary Medicine and Cardiology, Nurses, Pharmacists, PA-C and other healthcare professionals caring for anticoagulation patients. Educational Objectives After participating in this conference, attendees will be able to Explain recent developments in the treatment of VTE Identify which VTE does not need treatment Recognize which patients are candidates for reversal and the potential thromboembolic consequences of discontinuing and reversing anticoagulation Describe the role and clinical utility of reversal agents for various DOACs and explore other reversal agents that are currently in development Discuss the evidence to reverse warfarin with Vitamin K, FFP and PCC Describe anti-platelet and anticoagulation therapy relating to cardiology Discuss peri-procedural anticoagulation management and the role of the anticoagulation clinic Describe lysis therapy in the treatment of DVT and PE List anticoagulation quality metrics Faculty Marc Carrier, MD, MSc, FRCPC Senior Scientist, Clinical Epidemiology Program Ottawa Hospital Research Institute Associate Professor, Department of Medicine University of Ottawa Ottawa, Ontario James Froehlich, MD, MPH Director, Vascular Medicine Director, Anticoagulation Services Director, Michigan Cardiovascular Outcomes Research and Reporting Program (MCORRP) Asst. Chair of Medicine for Quality and Innovation Professor of Internal Medicine University of Michigan Medical School Samuel Z. Goldhaber, MD Director, Thrombosis Research Group Section Head, Vascular Medicine Professor of Medicine Harvard Medical School Boston, MA Christopher B. Granger, MD, FAHA, FACC Professor of Medicine Director, Cardiac Intensive Care Unit Duke University Medical Center Durham, North Carolina Clive Kearon, MB, MRCP(I), FRCP(C), PhD Jack Hirsh Professorship in Thromboembolism McMaster University Hamilton, Ontario Michael B. Streiff, MD Medical Director, Anticoagulation Management Service and Outpatient Clinics Staff Physician, Johns Hopkins Comprehensive Hemophilia Treatment Center Chairman, National Comprehensive Cancer Center Network s Venous Thromboembolism Guideline Committee Associate Professor, Johns Hopkins University School of Medicine Baltimore, MD Kim Tsilimingras, BS Pharm, MHA Director, Pharmacy Services Harper-Hutzel Hospital Rehabilitation Institute of Michigan Detroit Medical Center Sara Vazquez, PharmD, BCPS, CACP Clinical Pharmacist University of Utah Health Thrombosis Center Salt Lake City, Utah Scott Kaatz DO, MSc, FACP, SFHM Clinical Associate Professor of Medicine Wayne State Univeristy Senior Staff Hospitalist Medical Director for Professional Development and Research Division of Hospital Medicine Henry Ford Hospital Detroit, Michigan

Continuing Medical Education Statement The Wayne State University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Wayne State University School of Medicine designates this live activity for a maximum of 6.5 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity. Continuing Education Credit The Detroit Medical Center Department of Pharmacy Services is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. Pharmacists who attend the 18th Annual Antithrombotic Therapy Symposium, submit a completed Record of Program Attendance and evaluation forms for all programs attended and provide their NAPB e-profile number and four digit birthdate will be awarded a maximum of 6.25 hours (0.625 CEU) of continuing pharmacy education credit. A Statement of Continuing Pharmacy Education Credit will be available through CPE Monitor within 48 hours of completion of evaluation. Universal Activity Numbers (UAN): Session I (8:30 am Noon): 3 CEU 0510-999-17021-L01-P. Session II (1 2:30 pm): 1.5 CEU 0510-9999-17022-L01-P. Session III (2:45-4:15 pm): 1.5 CEU 0510-9999-17023-L01-P. Meeting Location The Dearborn Inn, A Marriott Hotel, is located at 20301 Oakwood Boulevard, Dearborn, Michigan 48124. Phone: (313) 271-2700, Website: http://www.marriott.com/hotels. Registration Fee There is $50.00 registration fee for all practicing physicians, pharmacists, physician assistants and nurses, $25.00 registration fee for fellows, residents and students. The registration fee includes continental breakfast, breaks, lunch, CME credits and course materials. On-line registration is now available at www.med.wayne.edu/cme or you may complete the registration form attached and either telephone, fax or mail it to: Wayne State University School of Medicine, Division of Continuing Medical Education, 4201 St. Antoine, UHC 9A Detroit, MI 48201. Phone (313)577-1180; fax (313)577-7554. All registrations will be confirmed by e-mail to the address provided on the registration form. Refund Policy A full refund, less a $25 processing fee will be granted to requests received in the CME office prior to April 14, 2017. No refunds will be granted for No-Shows. Provider This course is provided by the Wayne State University School of Medicine, Department of Internal Medicine. The lecture by Dr. Michael Streiff titled: The ABCs of Anticoagulation and Reversal: Do You Know Your DOACs? Was developed and delivered in cooperation with Boston University School of Medicine and the Anticoagulation Forum. Sponsor Wayne State University School of Medicine gratefully acknowledges the Platinum sponsorship of Pfizer and BMS, and the sponsorship of Janssen.

Agenda 7:30 8:20 a.m. Registration & Continental Breakfast 8:20 8:30 a.m. Opening Remarks Kim Tsilimingras, BS Pharm, MHA 8:30 9:15 a.m. Update on VTE Treatment Clive Kearon, MD, PhD 9:15 10:00 a.m. Which VTE Doesn t Need Treatment Marc Carrier, MD 10:00 10:15 a.m. Break 10:15 11:00 a.m. The ABCs of Anticoagulation and Reversal: Do You Know Your DOACs? Michael Streiff, MD 11:00 11:45 a.m. Cardiology Update on Anti-Platelet and Anticoagulation Therapy Christopher Granger, MD 11:45 12:00 p.m. Morning Panel 12:00 1:00 p.m. Lunch 1:00 1:30 p.m. Peri-Procedural Anticoagulation Management and the Role of the Anticoagulation Clinic Sara Vazquez, PharmD 1:30 2:15 p.m. The Latest on Lysis Samuel Goldhaber, MD 2:15 2:45 p.m. Anticoagulation Quality Metrics James Froehlich, MD, MPH 2:45 3:00 p.m. Break 3:00 4:15 p.m. Panel Discussion: Challenging Cases Moderator: Scott Kaatz, DO Panel: All speakers 4:15 p.m. Evaluation and Adjourn

18th Annual ANTITHROMBOTIC THERAPY SYMPOSIUM Friday, April 28, 2017 Dearborn Inn, Dearborn MI On-line Registration is available at First Name www.med.wayne.edu/cme Please print clearly, conference materials will be made from the information on this form Last Name Last Four Digits of Social Security Number Degree Mailing Address City State ZIP Phone ( ) Specialty E-mail (E-mail required for confirmation) Pharmacists Only: e-profile Number 4 Digit birthdate (MM/DD Fees: Please check one o Practicing Health Care Professionals $50.00 o Fellows, Residents and Students $25.00 Payment Method: please check one o Check (payable to Wayne State University) o Visa or MasterCard Card # Exp Date o Check here if you have a disability and may require accommodation to fully participate.you will be contacted by Wayne State University. Scan and email registrations to: dcme@med.wayne.edu Fax registration to: (313) 577-7554 Mail to: Continuing Medical Education Wayne State University School of Medicine 4201 St. Antoine; 9A-UHC Detroit, MI 48201 Telephone: (313) 577-1180 Fax: (313) 577-7554