October 21, 2016 THE WESTIN CHICAGO RIVER NORTH

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International Liver transplantation society Perioperative Care in Liver Transplantation 2016 Chicago, IL, USA October 21, 2016 THE WESTIN CHICAGO RIVER NORTH ILts.org www.ilts.org 1

Program Chair James Findlay, MD Mayo Clinic Rochester, MN, USA Program Committee Geraldine Diaz (Local co-chair) The University of Chicago Chicago, IL, USA Andre DeWolf, MD (Local co-chair) Northwestern University Feinberg School of Medicine Chicago, IL, USA Purpose The program is designed to update the participant on important issues involved with perioperative care during transplantation. Target Audience Anesthesiologists Critical Care Physicians Residents/Fellows Surgeons Transplant Coordinators Other Health Care Professionals interested in Perioperative Liver Transplant Care Hepatologists Dmitri Bezinover, MD Penn State University Hershey, Pennsylvania, USA Stuart McCluskey, MD, PhD, FRCPC University of Toronto Toronto, Canada Objectives 1. Review current management of cardiopulmonary complications of liver failure and transplantation with particular reference to intraoperative concerns. 2. Discuss the recent change in the allocation system for liver transplantation and how this may influence perioperative management. 3. Provide updates on the current management of pediatric liver transplantation and on current donor management techniques. Venue The Westin Chicago River North Astor Ballroom 320 N Dearborn St Chicago, IL 60654 Phone: (312) 744-1900 www.westinchicago.com Accreditation This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Amedco and International Liver Transplantation Society (ILTS). Amedco is accredited by the ACCME to provide continuing medical education for physicians. Credit Designation Statement Amedco designates this live activity for a maximum of 7.25 AMA PRA Category 1 Credits TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. www.ilts.org 2

Introduction 7:30 7:40 Opening Remarks and What s New at ILTS Andre DeWolf (Northwestern University, Chicago, IL, USA) and John Klinck (Cambridge University, Cambridge, UK) Session 1: Update on Pulmonary Comorbidities James Findlay (Mayo Clinic Rochester MN, USA) 7:40 8:00 Portopulmonary hypertension guidelines/management update Michael Krowka (Mayo Clinic, Rochester MN, USA) 8:00 8:20 Intraoperative pulmonary hypertension Tetsuro Sakai (University of Pittsburgh, Pittsburgh, PA, USA) 8:20 8:40 Hepatopulmonary syndrome Michael Ramsay (Baylor University, Dallas, TX, USA) 8:40 9:00 Discussion 9:00 9:20 Coffee Break Session 2: Cardiovascular Management Andre DeWolf (Northwestern University, Chicago, IL, USA) 9:20 9:40 Vasoplegia Gebhard Wagener (Columbia University, New York, NY, USA) 9:40 10:00 PPV - a useful tool in liver transplant? Cinnamon Sullivan (Emory University, Atlanta, GA, USA) 10:00 10:30 Pro/Con Debate: A low intraoperative CVP is the goal for Liver transplantation Pro: John Klinck (Cambridge University, Cambridge, UK) Con: John Feiner (University of California, San Francisco, CA, USA) 10:30 10:40 Discussion 10:40 11:00 Coffee Break www.ilts.org 3

Session 3: Perioperative Issues Stuart McCluskey (University of Toronto, Toronto, Canada) 11:00 11:20 NaMELD implications for practice Claus Fimmel (University of Chicago, Chicago, IL, USA) 11:20 11:40 Perioperative NA management Linda Liu (University of California, San Francisco, CA, USA) 11:40 12:00 Perioperative neurological complications Dmitri Bezinover (Pennsylvania State University, Hershey, PA, USA) 12:00 12:20 Discussion 12:20 13:00 Lunch Session 4: Moderated case discussions - panel Geraldine Diaz (University of Chicago, Chicago, IL, USA) 13:00 13:25 Case 1: A patient with NASH and postoperative NSTEMI Allen Gustin (Loyola University, Chicago, IL, USA) Presenter: Chris Cassara (Medical College of Wisconsin Milwaukee, WI, USA) 13:25 13:50 Case 2: Portopulmonary Hypertension and CAD Michael Ramsay (Baylor University, Dallas, TX, USA) Presenter: Elia Elia (Thomas Jefferson University, Philadelphia, PA, USA) 13:50 14:15 Case 3: A Case of Intraoperative Hypercoagulability in Pediatric Liver Transplantation Nicholas Wasson (Lurie Children s Hospital, Chicago, IL, USA) Presenter: Thomas Marshall (Ochsner Medical Center, Jefferson, LA, USA) 14:15 14:20 Q&A 14:20 14:40 Coffee Break www.ilts.org 4

Session 5: Donor Management and Pediatric update Moderators: Youri Vater (University of Washington, Seattle, WA, USA) and Joshua Herborn (Northwestern University, Chicago, IL, USA) 14:40 15:10 Donor management what s new and why it matters Claus Niemann (University of California, San Francisco, CA, USA) 15:10 15:40 Pediatric update Nicholas Wasson (Lurie Children s Hospital, Chicago, IL, USA) 15:40 16:00 Discussion Session 6: Scientific update Jeron Zerillo (Mount Sinai, New York, NY, USA) 16:00 16:20 Highlights from ILTS Seoul Congress Geraldine Diaz (University of Chicago, Chicago, USA) 16:20 16:40 End Notes best papers from ILTS Journal Club James Findlay (Mayo Clinic, Rochester, MN, USA) 16:40 16:50 Discussion 16:50 17:00 Closing Remarks Geraldine Diaz (University of Chicago, Chicago, USA) www.ilts.org 5

Registrant Information First/Given Name: Institution: Last/Family Name: Department: Address: City, State: Zip: Country: Phone: E-mail: Year of Birth: Demographic Information Degree MD PhD Other Affiliation Academic Private Practice Non-Physician Practice Type Research Clinical Primary Specialty Anesthesia Critical Care Medicine Liver Transplant Surgery GI/Hepatology Pediatrics Pathology Nursing Immunology Laboratory Medicine Pharmacology Radiology Secondary Specialty Anesthesia Critical Care Medicine Liver Transplant Surgery GI/Hepatology Pediatrics Pathology Nursing Immunology Laboratory Medicine Pharmacology Radiology Registration Fees *Please note: Membership includes a 12-month subscription to Transplantation, discounted registration at the ILTS/LICAGE/ELITA joint congress in Prague (May 2017), and full access to CME-approved lectures on the ILTS website. ILTS MEMBER Before Oct. 10 2016 Onsite NON -MEMBER Before Oct. 10, 2016 Onsite Attending/Specialist $ 110 $ 160 Attending/Specialist $ 350 $ 400 Allied Health/Scientist $ 100 $ 150 Allied Health/Scientist $ 240 $ 290 Trainee $ 95 $ 145 Trainee** $ 175 $ 225 **Trainees must include a letter from program director to document trainee status. Refund Policy Requests for refunds must be submitted in writing by Monday, October 10, 2016 Olga Gross, ogross@kit-group.org. A $25 processing fee will be deducted from your refund. Requests received after October 10, 2016 will not be honored. Payment Information Visa MasterCard American Express Credit Card Number: Cardholder s Name: Signature: Expiration Date: Security Code: Date: Send completed registration form to Olga Gross, by email, ogross@kit-group.org, or fax, 0049 30 246 03 200. www.ilts.org 6