Information Session August 2011

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University of Pittsburgh School of Medicine Physician Scientist Training Program (PSTP) Clinical Scientist Training Program (CSTP) Information Session August 2011

What is the PSTP? A highly competitive 5 year academic physician training program tailored to a student s specific research interests Integrated with School of Medicine curriculum An additional year of laboratory-based research training

What is the CSTP? Clinical Scientist Training Program 5 year merit scholarship program with the opportunity to complete a dual degree Earn 2 degrees in 5 years! (MD/MS) Competitive merit-based scholarship program $25,000/year for MD (MS-1, MS-2, MS-3, MS-4) Full tuition coverage for MS during Research Year (RY) between MS-3 and MS-4 At least $10,000 living stipend during RY Institute for Clinical Research Education

NIH Funding Out of 3400 Institutions nationwide that receive funding: - University of Pittsburgh ranked 5th (2009) - University of Pittsburgh ranked 4th in individual grants received (2006) Our university s consistently high ranking among the top recipients of competitively awarded NIH funds is clear evidence of the pioneering research being completed by our faculty, and we are extremely proud of this record. Chancellor Mark A. Nordenberg, Pitt Chronicle January 2, 2008

What Does This Mean? Pitt has invested significantly in new research infrastructure in disciplines such as: Developmental biology Cellular biology Structural biology Computational biology Faculty recruitment

Areas of Research Drug discovery & design Organ transplantation / Immunology Stem cell therapy Tissue engineering & regenerative medicine Artificial organ & medical device development Cancer diagnostics & therapy Cardiology Gene therapy Bioinformatics & computational biology Psychiatry Neuroscience Neurological surgery Vaccine development Hemostasis & vascular biology Structural biology Developmental biology Clinical trials management

Current Centers of Research Alzheimer Disease Research Center Arthritis Institute Center for Biological Imaging Center for Computational Biology & Bioinformatics Center for Image-guided Neurosurgery Center for Minority Health Center for Molecular Analysis Center for the Neural Basis of Cognition Center for Neuroscience Department of Bioinformatics Magee-Womens Research Institute McGowan Institute for Regenerative Medicine Pittsburgh Supercomputing Center Robotics Institute University of Pittsburgh Cancer Institute Western Psychiatric Institute and Clinic

City of Pittsburgh America s Most Livable City (Places Rated Almanac 2007) 10 th Cleanest City (Forbes 2007) 13 th Best City for Young Professionals to Live (Forbes 2008) Economy based on healthcare, education, technology, robotics, & financial services Housing market is relatively stable despite economic crisis Economy has added jobs despite national recession Extensive county & city parks offer miles of bicycle & walking trails Vibrant symphony, ballet, opera, & Broadway series Amateur & professional sports teams Well known attractions (museums, zoo, aviary, theaters) Home to 90 distinct neighborhoods (including Oakland, Shadyside, Squirrel Hill, Point Breeze, Highland Park all are a quick walk or bus ride away from the university)

Medical Student Opportunities Medical Scientist Training Program (MSTP) Clinical Scientist Training Program (CSTP) Physician Scientist Training Program (PSTP)

Physician Scientist Training Program (PSTP) Scholarship Program Complete in 5 years MD Stipend support * Focused on academic medicine & basic research Could transfer to MSTP (MD/PhD) -1 student Apply at onset and during 2 nd year * Stipend support during research year and summer lab rotations

PSTP Student Attributes Stood out in undergraduate years Have medical and research training Interested in generating biomedical breakthroughs Highly motivated Curious Focused

PSTP Curriculum - MS1 Summer Fall Spring Laboratory Rotation 1 Professional Development 1 Course (formally Molecular Medicine) Attend Retreat Research Integrity Course Research Basis of Medical Knowledge 1 Required SOM Courses (includes Scholarly Project) Ethics Course (twice annually) Meet with Career Advisor Meet with Career Advisor Work in Progress Seminar (WIP) - Monthly

PSTP Curriculum MS2 Summer Fall Spring Laboratory Rotation 2 Professional Development 2 Course Attend Retreat Required SOM Courses (includes Scholarly Project) Research Basis of Medical Knowledge 1 Ethics Course (twice annually) Meet with Career Advisor Meet with Career Advisor Work in Progress Seminar (WIP) - Monthly

PSTP Curriculum Research Year Summer Fall Spring Project Proposal (3 months in advance) Attend Retreat Progress Report (Oct) Ethics Course (twice annually) Meet with Career Advisor Progress Report (Feb) Final Report (May) Meet with Career Advisor Work in Progress Seminar (WIP) - Monthly

PSTP Curriculum MS3 Summer Fall Spring Required SOM Courses (includes Scholarly Project) Attend Retreat Ethics Course (twice annually) Meet with Career Advisor Meet with Career Advisor Work in Progress Seminar (WIP) - Monthly

PSTP Curriculum MS4 Summer Fall Spring Required SOM Courses (includes Scholarly Project) Attend Retreat Ethics Course (twice annually) Meet with Career Advisor Meet with Career Advisor Work in Progress Seminar (WIP) - Monthly

Why PSTP? Enhanced SOM curriculum Summer laboratory rotations Research related courses Year devoted to basic biomedical research Tuition scholarship & stipend support* Customized & guided program by a Career Advisor World renowned facilities & faculty Phenomenal collection of programs

Application Process Apply individually to SOM & PSTP Very important to complete MD & PSTP applications as soon as possible Must apply online to PSTP (including letters of recommendation) Deadline February 1 Expect to receive 60 applications Maximum of 4 positions available (includes 2 internally)

Application Criteria Written PSTP Application Outstanding academic record (~ GPA 3.7 & MCAT 36) 2 Letters of Recommendation Prior research experience Evidence of commitment to a career as a physician scientist

Interview Process Review application & letters of recommendation Approximately 20 applicants will be offered interviews (which is required and in addition to SOM interview) Must be accepted/waitlisted to SOM by Feb 15 to be considered for interview PSTP Interviews are at our expense

Application Statistics Academic Year 2008-2009 Academic Year 2009-2010 Academic Year 2010-2011 54 Applicants 63 Applicants 41 Applicants 18 Interviewed 19 Interviewed 21 Interviewed 12 Accepted 6 Accepted / 3 Waitlisted 6 Accepted / 3 Waitlisted 7 Matriculated (3.88 GPA / 11.17 MCAT) 6 Matriculated (3.70 GPA / 12.11 MCAT) 6 Matriculated (3.93 GPA / 12.17 MCAT)

PSTP Contacts Richard Steinman, MD, PhD Director, Physician Scientist Training Program Clayton Steup, MS Program Coordinator Contact Information: 412-624-6074 pstp@medschool.pitt.edu www.pstp.pitt.edu

Medical Student Opportunities Medical Scientist Training Program (MSTP) Clinical Scientist Training Program (CSTP) Physician Scientist Training Program (PSTP)

What is clinical research? Clinical Research is distinguished from basic science research by its reliance upon human subjects. patient-oriented research conducted with human subjects, or research on the causes and consequences of disease in human populations involving material of human origin (such as tissue specimens and cognitive phenomena) for which an investigator or colleague directly interacts with human subjects in an outpatient or inpatient setting to clarify a problem in human physiology, pathophysiology or disease, or epidemiologic or behavioral studies, outcomes research or health services research, or developing new technologies, therapeutic interventions, or clinical trials. [NIH] Goal of Clinical Research: advance translation of basic biomedical research discoveries into treatments, preventions, and cures that will improve human health Institute for Clinical Research Education

Clinical Scientist Training Program (CSTP) Upon completion of the program students will have the following competencies: Research Methods Data Management and Analysis Ethical Conduct of Research Research Communication/ Dissemination Professionalism and Teamwork Institute for Clinical Research Education

CSTP Curriculum: MS-1 Fall Spring University of Pittsburgh School of Medicine course work CSTP Seminar: Introduction to Clinical and Translational Research CSTP Seminar: Seminar for Understanding Principles and Practices of Research Techniques (SUPPORT) (1) Saturday Survival Skills and Ethics Workshop Apply for summer research program Annual Review Institute for Clinical Research Education

CSTP Curriculum MS-2 Summer Fall Spring Mentored research project University of Pittsburgh School of Medicine course work (exempt from Scholarly Project)* CSTP Seminar: Seminar for Understanding Principles and Practices of Research Techniques (SUPPORT) (1) Saturday Survival Skills and Ethics Workshop Annual Review *All CSTP students meet the Scholarly Project requirement through their MS thesis. CSTP students are exempt from all Scholarly Project monitoring and paperwork Institute for Clinical Research Education

CSTP Curriculum MS-3 Summer Fall Spring None University of Pittsburgh School of Medicine course work Keep in touch with CSTP program director and mentor(s) Apply for a competitive research fellowship to provide more funding during research Annual Review Institute for Clinical Research Education

CSTP Curriculum Research Year (RY) Summer Fall Spring Take core classes towards MS CSTP Seminar: Seminar for Understanding Principles and Practices of Research Techniques (SUPPORT) (2) Office of Academic Career Development Workshops ICRE courses- MS electives and specialty track (30 credits to complete MS) Mid-point Review Annual Review Institute for Clinical Research Education

CSTP Curriculum MS-4 Summer Fall Spring University of Pittsburgh School of Medicine course work Defend Thesis for MS Complete exit survey Institute for Clinical Research Education

2 degrees in 5 years (MD/MS) Why CSTP? Build a lifelong relationship with an NIH-funded mentor Small, supportive cohort of fellow CSTP students with similar interests Debt reduction Allows for future career flexibility More Competitive for residency MS and 2 first author publications Year off between MS-3 and MS-4 Reflect on specialty choice before having to apply for residency Institute for Clinical Research Education

Application Process Apply individually to SOM and CSTP Must complete CSTP application by February 1 Application includes: demographic and administrative data two short essay questions personal statement curriculum vitae two letters of recommendation two references No formal interview process; applicants are encouraged to schedule a phone conversation with Associate Program Director Maximum of 5 positions available per year Institute for Clinical Research Education

What are we looking for? Prior activities demonstrating leadership, creative thought, and/or innovative research Compelling personal statement Enthusiasm/investment in your prior research Commitment to academic medicine Details regarding your particular interest in potential Pitt mentors Excellent academic performance Average MCAT: 12.0 Average GPA: 3.76 Strong letters of recommendation We are interested in your commitment to a career in clinical investigation, not whether you would be a good doctor Institute for Clinical Research Education

Student Testimonials In addition to breadth of clinical research exposure, who with I can share research frustrations, advice, and the difficulty of integrating longitudinal research into medical school curriculum. Ben Sprague class of 2013 I have been involved with like-minded individuals equally set on careers in clinical research and have. Tiffany Behringer class of 2012 Between the formal program activities and the mentored research experience,, intellectually, professionally, and socially. Sarah Ramer class of 2012 I cannot adequately express the extent to which,. Reva Pomerantz class of 2011 Institute for Clinical Research Education

CSTP Contacts Wishwa N. Kapoor, MD, MPH Director, Institute for Clinical Research Education Amber E. Barnato, MD, MPH, MS Director, Clinical Scientist Training Program for Medical Students Debra Bogen, MD Associate Director, Clinical Scientist Training Program for Medical Students Jennifer Holliman, MPA Degree Program Coordinator Tara Rohall Program Coordinator, Clinical Scientist Training Program for Medical Students For more information, please visit our website: http://www.icre.pitt.edu/cstp-m/index.aspx All inquiries may be directed to: cstp@pitt.edu Institute for Clinical Research Education