Biological Methylation: Fundamental Mechanisms in Human Health and Disease

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Biological Methylation: Fundamental Mechanisms in Human Health and Disease Hilton Florence Metropole Florence, Italy June 17 22, 2018 Co-organizers: Dr. Maria Elena Torres-Padilla Associate Professor, Institute of Epigenetics and Stem Cells Helmholtz Zentrum München Dr. Xiaobing Shi Associate Professor, Epigenetics and Mol. Carcinogenesis The University of Texas M.D. Anderson Cancer Center

Sunday, June 17 4:00-9:00pm 4:45-5:00pm 5:00-6:00pm 6:00-7:00pm Conference Registration Welcome from FASEB and the organizers The EMBO Keynote Lecture Kristian Helin, University of Copenhagen Histone methylation and human cancer Welcome reception Monday, June 18 7:30-12:00pm 9:00-12:00pm 10:30-11:00am 11:00-11:30am 11:30-11:45am 12:00-1:00pm 1:00-2:00pm 2:00-4:00pm 4:00-5:00pm 5:00-6:30pm 5:00-5:30pm Conference Registration Session 1: Methylation and chromatin regulation Chair: Paul Wade, NIH Thomas Jenuwein, Max Planck Institute of Immunology and Epigenetics Robert Schneider, Institute of Functional Epigenetics, Munich and GROUP PHOTO Jerry Workman, Stowers Institute LUNCH and Meet the Experts Career Development Workshops Keynote address Tom Muir, Princeton University Protein methylation: chemistry and beyond Session 2: Quantitative approaches to protein methylation Chair: Ernesto Guccione, Institute of Molecular and Cell Biology-A Star Ben Garcia, Perelman School of Medicine University of Pennsylvania

5:30-6:00pm 6:00-6:15pm 6:15-6:30pm 5:00-8:00pm Axel Imhof, Ludwig Maximilian University of Munich Conference Registration 8:00-10:00pm POSTER SESSION 1 Tuesday, June 19 11:15-11:45am 12:00-12:15pm 12:15-1:15pm 1:15-5:00pm 5:00-7:00pm 5:00-5:30pm 5:30-6:00pm 6:00-6:30pm 6:30-7:00pm Session 3: Protein methylation in development and disease Chair: Maria Elena Torres-Padilla, Helmholtz Zentrum Muenchen Or Gozani, Stanford University Jonathan Whetstine, Harvard Medical School Rob Klose, University of Oxford Jürg Müller, Max Planck Institute of Biochemistry LUNCH Session 4: Arginine methylation: players and mechanisms Chair: Uta Maria Bauer, Institute of Molecular Biology and Tumor Research Mark Bedford, MD Anderson Cancer Center Stéphane Richard, McGill University Ernesto Guccione, Institute of Molecular and Cell Biology - A Star Steven Clark, UCLA 8:00-10:00pm POSTER SESSION 2

Wednesday, June 20 11:15-11:45am 12:00-12:15pm 12:15-1:15pm 1:15-7:00pm 8:00-9:30pm 8:00-8:15pm 8:15-8:30pm 8:30-8:40pm 8:45-9:00pm 9:00-9:15pm 9:15-9:30pm Session 5: Modifications of nucleic acids Chair: Taiping Chen, MD Anderson Cancer Center Anjana Rao, La Jolla Institute For Allergy and Immunology Peter Jones, Van Andel Institute Chuan He, University of Chicago Andrew Xiao, Yale University LUNCH TECHNOLOGY WORKSHOP SESSION Thursday, June 21 0:00-10:15am Session 6: Modulating methylation in disease and aging Chair: Xiaobing Shi, MD Anderson Cancer Center Yang Shi, Harvard Medical School Yali Dou, University of Michigan, Ann Arbor

11:15-11:45am 12:00-12:15pm 12:15-1:15pm 1:15-4:30pm 4:30-6:30pm 4:30-5:00pm 5:00-5:30pm 5:30-6:00pm 6:00-6:30pm 8:00-10:00pm 8:00-8:30pm 8:30-9:00pm 9:00-9:15pm 9:15-9:30pm 9:30-10pm Mark Dawson, Peter MacCallum Cancer Centre Panagis Filippakopoulos, Ludwig Institute for Cancer LUNCH Session 7: Structural insights to protein methylation Chair: Rui-Ming Xu, Chinese Academy of Sciences Dinshaw Patel, Memorial Sloan Kettering Cancer Center Cheryl Arrowsmith, Structural Genomics Consortium, Canada Xiaodong Cheng, MD Anderson Cancer Center Tatiana Kutateladze, University of Colorado Session 8: Methylation and Therapeutics Chair: Paula Vertino, Emory University Brian Strahl, University of North Carolina at Chapel Hill Karsten Rippe, Universität Heidelberg Business meeting Friday, June 22 Session 9: Methylation dynamics and transcription control Chair: Yali Dou, University of Michigan, Ann Arbor (?) Steve Jacobsen, UCLA Kai Ge, NIH Anja Groth, University of Copenhagen

11:15-11:30am 11:30-11:45am 12:00-1pm Closing Remarks LUNCH and DEPART END OF CONFERENCE For additional information contact: FASEB Science Research Conferences 9650 Rockville Pike, Bethesda, MD 20814 www.faseb.org/src