VIRGINIA. Bioscience Performance Metrics. Virginia Page 1

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VIRGINIA Virginia s largest bioscience subsector is research, testing, and medical laboratories (10,396 jobs), where it has outpaced the nation in subsector job growth since 2001. Total academic bioscience research and development expenditures in Virginia have grown by 23 percent since and reached $550 million in, led by medical and biological sciences. The State s biomedical institutions participated in 408 active clinical trials in. Its higher education institutions play a key role in developing talent with 4,146 students graduating with degrees in bioscience related fields. In the last six years, venture capital invested in bioscience companies in Virginia totaled $406 million, with a peak in. Most VC funding went to companies engaged in medical/health information technology, human biotechnology, and medical/health products. The 1,038 bioscience patents issued to Virginia inventors over the same six year period were led by drugs and pharmaceuticals, surgical and medical instruments, and biochemistry. Bioscience Performance Metrics Summary of State Performance in Selected Bioscience related Metrics Metrics Virginia United States Rank* Bioscience Industry, Total Bioscience Industry Employment, 20,257 1,420,324 III Bioscience Industry Location Quotient, 0.54 n/a IV Biosciences Industry Establishments, 981 47,593 II Academic R&D Expenditures, FY Bioscience R&D ($ thousands) $549,990 $31,818,810 17 Bioscience Share of Total R&D 52.3% 61.3% 37 Bioscience R&D Per Capita $70.55 $104.54 38 Change in Bioscience R&D, FY 08 23.4% 22.3% 18 NIH Funding, FY Total, Including ARRA Funds ($ thousands) $380,289 $25,837,590 19 Per Capita Funding $48.24 $84.16 32 Change in Baseline Funding, FY 09** 34.8% 4.7% 52 Change in Total Funding, FY 09 21.1% 14.6% 52 Clinical Trials, Initiated 408 5,299 18 Higher Education Degrees in Bioscience Fields, AY 4,146 161,811 11 Employment in Bioscience related Occupations, 15,280 717,510 17 Bioscience Venture Capital Investments, 09 ($ millions) $405.9 $60,099 19 Bioscience and Related Patents, 09 1,038 75,593 23 *State ranking figures for bioscience industry employment metrics are calculated as quintiles (I=Top Quintile; V=Bottom Quintile). All other metrics are ranked 1 52. **Baseline Funding does not include American Recovery and Reinvestment Act (ARRA) funds for. For source notes, see end of State Profile. Virginia Page 1

Bioscience Industry Base, INDUSTRY SUBSECTOR Virginia United States 2001 08 Change 2001 08 Change AGRICULTURAL FEEDSTOCK & CHEMICALS Establishments 34 5.4% 2,440 16.0% Employment 2,621 9.3% 114,793 1.9% Location Quotient 0.87 n/a Direct Effect Employment Multiplier 5.08 11.33 Total Employment Impact 13,314 1,284,650 Average Annual Wage $81,647 $72,279 DRUGS & PHARMACEUTICALS Establishments 30 15.4% 2,771 6.4% Employment 3,606 2.6% 311,882 2.3% Location Quotient 0.44 n/a Direct Effect Employment Multiplier 5.33 9.92 Total Employment Impact 19,218 2,873,278 Average Annual Wage $76,471 $93,378 MEDICAL DEVICES & EQUIPMENT Establishments 333 23.8% 15,227 0.4% Employment 3,634 14.0% 435,509 2.0% Location Quotient 0.32 n/a Direct Effect Employment Multiplier 2.37 4.87 Total Employment Impact 8,621 2,029,581 Average Annual Wage $43,198 $63,606 RESEARCH, TESTING, & MEDICAL LABORATORIES Establishments 584 91.7% 27,154 57.7% Employment 10,396 82.4% 558,140 46.1% Location Quotient 0.71 n/a Direct Effect Employment Multiplier 2.39 3.30 Total Employment Impact 24,868 1,853,127 Average Annual Wage $68,453 $80,785 TOTAL BIOSCIENCES INDUSTRY Establishments 981 55.2% 47,593 28.3% Employment 20,257 22.7% 1,420,324 15.8% Location Quotient 0.54 n/a Direct Effect Employment Multiplier 3.26 5.82 Total Employment Impact 66,021 8,040,636 Average Annual Wage $67,058 $77,595 TOTAL PRIVATE SECTOR Establishments 223,390 17.6% 8,860,956 13.8% Employment 2,990,515 5.8% 113,917,377 3.5% Average Annual Wage $46,703 $45,229 Note: U.S. employment metrics include Puerto Rico. Estimates of total employment impacts do not include Puerto Rico. Virginia Page 2

Bioscience Performance Metrics Bioscience Academic R&D Expenditures in Virginia, FY NIH Awards in Virginia, Medical $228,500 $482 Biological $190,455 $491 Agricultural Other Life $16,599 $98,613 $331 $379 $438 Bio/Biomedical Engineering $15,823 ARRA $380 $0 $50,000 $100,000 $150,000 $200,000 $250,000 Academic R&D Expenditures ($ Thousands) $0 $100 $200 $300 $400 $500 NIH Funding ($ Millions) Recent Clinical Trial Activities Clinical Trials by Phase in Virginia, Phase I 22 Clinical Trials by Major Disease Category in Virginia, 120 100 103 104 Phase II 126 80 60 83 65 79 Phase III 171 40 35 41 20 Phase IV 25 0 30 60 90 120 150 180 0 Cancer Circulatory Heart Disease Infectious Disease Neurologic Nutritional & Metabolic Other Clinical Trials Disease Category Virginia Page 3

Bioscience Talent Base Bioscience related Occupational Employment in Virginia, Bioscience related Degrees in Virginia, AY Agricultural, Food & Nutrition Scientists & Technicians 680 Agricultural, Food, & Nutrition Science Biological Scientists & Technicians Medical & Clinical Laboratory Technicians Biomedical & Biochemical Scientists & Engineers 570 2,920 11,110 Biological Bio Medical & Engineering Medical & Veterinary Other Life Science Fields Associate's (AA/AS) Bachelor's (BS/BA) Master's (MS/MA) Doctorate (PhD) 0 2,000 4,000 6,000 8,000 10,000 12,000 Occupational Employment 0 500 1,000 1,500 2,000 2,500 3,000 Degrees Bioscience Venture Capital Bioscience related Venture Capital Investments in Virginia, Bioscience related Venture Capital Investments in Virginia by Segment, $36.8 Biofuels Biosensors $5.0 $57.8 Biotech Animal $22.0 Biotech Equipment Biotech Human $99.3 $73.0 Biotech Industrial Biotech Other $0.1 $158.4 Biotech Research $5.0 $57.9 Med/Health Info Tech Med/Health Products $84.9 $168.7 $0 $40 $80 $120 $160 Med/Health Services $25.7 Venture Capital Investments ($ Millions) Medical Diagnostics Medical Therapeutics Pharmaceutical $0.1 $1.3 $15.8 $0 $50 $100 $150 $200 Venture Capital Investments ($ Millions) Virginia Page 4

Bioscience Patents Bioscience related Patents in Virginia, Bioscience related Patents by Classification Group in Virginia, 174 Agricultural Bioscience 13 158 Biochemistry 227 189 176 173 168 0 50 100 150 200 Patents Biotechnology Drugs & Pharmaceuticals Surgical & Medical Instruments Other Medical Equipment Other Bioscience Related 14 132 141 0 50 100 150 200 250 300 Patents 246 265 State Bioscience Contact Virginia Biotechnology Association 800 East Leigh Street, Suite 14 Richmond, VA 23219 P: (804) 643 6360 F: (804) 643 6361 www.vabio.org Source Notes: Employment, Establishment, and Wage Data: U.S. Bureau of Labor Statistics, Quarterly Census of Employment and Wages (QCEW) industry data provided by the Minnesota IMPLAN Group, 2001 and. Employment Multipliers: U.S. Bureau of Economic Analysis RIMS II Employment Multipliers, (most currently available). Academic R&D Expenditures: National Science Foundation (NSF) Survey of Research and Development Expenditures at Universities and Colleges, and. NIH Funding: National Institutes of Health, Office of Extramural Research, Award Trends, Dollars Awarded by State, and. Clinical Trials: National Institutes of Health, Clinicaltrials.gov, trials that were initiated in. Higher Education Degrees: National Center for Educational Statistics, Integrated Postsecondary Education Data System (IPEDS),. Occupational Employment: U.S. Bureau of Labor Statistics, Occupational Employment Statistics (OES) survey data,. Venture Capital: Thomson Reuters VentureXpert Database,, as of January 15, 2010. Patents: U.S. Patent & Trademark Office data as available from the Thomson Reuters Delphion Patent Analysis Database,, as of January 15, 2010. For a more detailed discussion of the data and methodology used, please see the Appendix to the full national report. 2010 Virginia Page 5