Podiatry Clinical Director Department of Surgery / Surgery Department Podiatry Section University of Colorado Health Sciences Center

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Dr. Florin Costache Cherry Creek Foot Clinic Owner/Podiatrist 2017 Present Podiatry Clinical Director 2003-2017 Department of Surgery / Surgery Department Podiatry Section Assistant Professor, Clinical Director 2002-2003 Division: Plastic & Reconstructive Surgery Podiatry Section Assistant Professor 1999-2002 Department of Surgery, Podiatry Section Instructor 1996-1999 Department of Surgery, Podiatry Section Clinical Instructor, Externship Director 1998 1999 Veterans Administration Medical Center Private Practice 1996-1999 Florin Costache, DPM Academic Degrees: B.S. Biology State University of New York at Albany 1987 1991 1400 Washington Ave., Albany NY 12222 D.P.M Kent State University College of Podiatric 1991-1995 Medicine, (formerly known as The Ohio College of Podiatric Medicine) 6000 Rockside Woods Blvd., Independence OH 44131 Residency Podiatric Orthopedic Residency 1995 1996

Podiatric Surgical Residency 1996-1997 Fellowship Diabetic Foot Surgery/Research Fellowship 1997-1998 Board Certification American Board of Foot & Ankle Surgery 2005 - Present State Licensure State of Colorado # 496 1996 - Present Continuing Medical Education as per CO State Committees National and Local Operating Room Committee, University of 2001-2010 Colorado Hospital Colorado Podiatric Medical Association 2004 2006 Board of Directors Appeals Panel Committee / Anthem-Blue Cross 2004-2010 and Blue Shield and HMO Colorado UC Denver, Conflict of Interest and Commitment 2011-2012 Committee UPI CREDENTIALING COMMITTEE 2011-2017 Expert Case Review Elite Medical Experts-Medical legal case review 2015 - Present and Expert Testimony Community Activities 9 Health Fair-foot and ankle screening and special 2001 - Present focus on the diabetic foot-aurora and Denver Shoes and Socks for the Homeless 2004 - Present Summer Health Institute mentor for Job Shadowing 2004 Women s Integrated Services in Health, Volunteer 2007

Regional Invited Lectures: 35 th Annual Internal Medicine Program, Estes Park, CO (Guest Lecturer) 1999 Topic: Podiatry / Primary Care 24 th National Primary Care Nurse Practitioner Symposium, Keystone, CO 1999 Topic: Diabetic Foot Johnson & Johnson Wound Management -(Guest Lecturer) 2004 Use of Regranex Gel in Diabetic Wounds Visiting Professor Division of General Internal Medicine, University of Colorado Hospital. 2006 Topic: Challenges in the Diabetic Foot Grand Rounds 2013-2017 General Internal Medicine-University of Colorado/School of Medicine Primary Foot Care and Foot and Leg Trauma Vascular Conference Diagnosis and Treatment of Diabetic Charcot Arthropathy 2014-2017 Teaching UCH Inpatient Duties: Inpatient resident and fellow teaching 1999-2017 Clinical: Rheumatology Fellow Podiatry Rotation 2001-2017 Internal Medicine Resident Rotation 2004-2017 Operative Room: Anesthesia Residents 1999-2017 Certified Nurse Practitioners 1999-2017 Course Development: Internal Medicine-Resident Goals and Objectives 2006-2017 as it applies to foot and ankle evaluation Ongoing Clinical and Operative Room Research Projects Tendo Achilles Lengthening and its role in Forefoot Surgery Prevent forefoot Lesions in Diabetics Use in common foot procedures to increase the short term and long term success of forefoot procedures Review of Soft Tissue tumors/masses in the foot Case studies, with use of histology slides Plantar Fascitis-Review-Case Study-Fracture

Case study and review of rare occurrence Ankle Equinus Long term data collection to show the influence of ankle equinus on the lower extremity, how it prevents the successful treatment of common foot and ankle pathology when the ankle equinus is not addressed. Bleomycin Treatments of Plantar Verruca Long term use to show its efficacy when compared to all the other current available treatments. Plan to propose its use in patch form and approach industry for this study and its delivery to the market. Surgical Procedure Upgrades Hallux Rigidus Osteotomy Keller Arthroplasty Modification Keller Arthroplasty and the use of biologic products-case study Case Studies Jobs Syndrome Presentation in the Foot and Ankle. Levaquin induced Achilles tendon rupture. Singulair and its adverse effects on foot surgery. Polypropylene mesh use in complete Achilles tendon rupture. Gout vs. Hallux Rigidus. Primary Closure of Chronic Wounds Plastic techniques, undermining of subcutaneous tissue to advance and close chronic wounds, decrease the use of grafting for foot and ankle larger and chronic wounds. Efficacy of Custom Polypropylene-Rigid Orthotics Long term data collection that tracks the use, compliance and symptom relief for lower extremity pathology, both for short term and long term. 1 st MTPJ Cutout with Polypropylene Custom Orthotics Compare cutout vs. the neutral forefoot posting type orthtotics. Use of Rocker Bottom Correction with Diabetic Shoe Premise for the diabetic patient and the increased tightness of the Achilles tendon. Such pathology creates forefoot pressure lesions, breakdown in the midfoot architecture of the foot and encourages Charcot foot along with its destructive properties, chronic ulcerations and amputation. Long term prevention of such pathology when the rocker bottom is incorporated.