Principles of Biology Lab

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Class code BIOL-UA 9123 002 (Lab) Instructors Details Dr Matthew Brandley mcb18@nyu.edu Consultations by Appointment Please allow at least 24 hours for your instructors to respond to your emails. Class Details Spring 2017 Thursday 9:00 12:00pm (Lab) February 2 to May 4 University of Technology Sydney (UTS) Science Lab CB04.04.561 Building 4, 745 Harris Street, Ultimo, NSW 2007 Prerequisites Principles of Biology I Class Description The lab is organised into several modules, each with one or more experiments that cover different biological fields (see the syllabus for a detailed explanation and presentation of the lab structure, time-line, rules and grade breakdown). Some experiments run for multiple meetings over the course of several weeks, while other experiments stand-alone -- beginning and finishing in one meeting. Some experiments have a hypothesis-based component, while other experiments are observational. During the course of the semester there are various assignments and tests to prep you for the lab. Desired Outcomes Biology is quickly advancing and evolving. It is important that we keep up with changes and stay at the forefront. New discoveries and technologies in molecular biology and genomics are transforming biological research so that now we can do more than look at the phenotype of an organism or a community, but we can also examine the genes that regulate the way an organism looks or behaves or even how it has evolved. Page 1 of 8 At the same time we also pay homage to the traditional approaches in biology, whether that means looking at fixed samples on a slide in the microscope or examining preserved or living specimens. This approach is expansive, yet designed to give you experience with biological techniques that are fundamental to contemporary research labs.

Our hope is that every student who takes this introductory biology course leaves with a sense of the potentials in biology today. Assessment Components Five Homework Assignments (20% or 4% each) due dates in Weekly Schedule Each assignment will require reading a scientific journal article and answering short answer questions. Ten Post-lab Assignments (25% or 2.5% each) due dates in Weekly Schedule There are five questions for each lab. Each question is worth 0.5 points. Three Practical Quizzes (15% or 5% each) in Weeks 5, 9, 12 (15 minutes each) There are five two-part questions for each quiz practical. Each question is worth 0.5 points. Writing Assignment (15%) in three parts Introduction and Materials and Methods (5%): due Week 5 Results and Discussion (5%): due Week 8 Introduction, Materials & Methods, Results and Discussion, (5% edited and unified into one document): due Week 10 Lab Practical Exam (20%) Week 14, Thu 4 May (1 hour) There are 20 two-part questions in the final exam. Each is worth 0.5 points. Lab Participation (5%) Failure to submit or fulfill any required course component will result in failure of the class. For this course your total numerical score, calculated from the components listed above, is converted to a letter grade without rounding. Assessment Expectations Grade A: Excellent work showing a thorough knowledge and understanding of the topics, with excellent use of scientific language, detailed analysis and clear logical explanations, showing insight, independent, original thought and reasoning. Grade B: Good work with good general knowledge and understanding of the topics, accurate use of scientific language, good general analysis and coherent explanations showing some independent reasoning, reading and research. Grade C: Satisfactory work, broadly correct both factually and analytically, with some explanation and reasoning: the work will typically demonstrate a basic understanding of the topic. Grade D: Passable work, showing a general, superficial knowledge and understanding of the Page 2 of 8

topic, lacking satisfactory use of scientific language or adequate analysis. Grade F: Unsatisfactory work in all criteria. Grade Conversions For this course your total numerical score, calculated from the components listed above, correspond to the following letter grades: A 90 to 100 A- 86 to < 90 B+ 82 to < 86 B 72 to < 82 B- 68 to <72 C+ 64 to <68 C 54 to <64 C- 50 to <54 D+ 45 to <50 D 40 to <45 F 0 to <40 Submission of Work Should work be submitted as a hard copy, or electronically? Unless otherwise specified, all written work must be submitted as a hard copy. The majority of written assignments must also be submitted electronically via NYU Classes. All in-class presentations must be completed during class time. Who may submit a student s work? Each student s assigned work must be handed in personally by that student. The student may not nominate another person to act on his/her behalf. When and where should the work be submitted? The hard copy of any written work must be submitted to the instructor at the beginning of class on the date the work is due. If the assignment due date falls outside of class time, work must be submitted to the Staff Member on duty in Room 2.04 during prescribed Office Hours (11:30am-12:30pm and 2:30-3:30pm Mon-Thu), or by appointment with the Academic Programs Coordinator. Each submitted item of work received in Room 2.04 will be date and time stamped in the presence of the student. Work submitted in Room 2.04 will not be considered received unless formally stamped. What is the Process for Late Submission of Work? After the due date, work may only be submitted under the following conditions: Late work, even if an extension has been granted, must be submitted in person by appointment with the Academic Programs Coordinator. Each submitted item of work must be date and time stamped in order to be considered received. Page 3 of 8

Work submitted after the submission time without an agreed extension receives a penalty of 2 points on the 100-point scale (for the assignment) for each day the work is late. Written work submitted beyond five weekdays after the submission date without an agreed extension receives a mark of zero, and the student is not entitled to feedback for that piece of work. Because failure to submit or fulfil any required course component will result in failure of the course, it is crucial for students to submit every assignment even when it will receive a mark of zero. Early departure from the program therefore places the student at risk of failing the course. Plagiarism Policy The academic standards of New York University apply to all coursework at NYU Sydney. NYU Sydney policies are in accordance with New York University s plagiarism policy. The presentation of another person s words, ideas, judgment, images or data as though they were your own, whether intentionally or unintentionally, constitutes an act of plagiarism. It is a serious academic offense to use the work of others (written, printed or in any other form) without acknowledgement. Cases of plagiarism are not dealt with by your instructor. They are referred to the Director, who will determine the appropriate penalty (up to and including failure in the course as a whole) taking into account the codes of conduct and academic standards for NYU s various schools and colleges. Attendance Policy Study abroad at Global Academic Centres is an academically intensive and immersive experience, in which students from a wide range of backgrounds exchange ideas in discussion-based seminars. Learning in such an environment depends on the active participation of all students. And since classes typically meet once or twice a week, even a single absence can cause a student to miss a significant portion of a course. To ensure the integrity of this academic experience, class attendance at the centres is mandatory, and unexcused absences will affect students' semester grades. The class roster will be marked at the beginning of class and anyone who arrives after this time will be considered absent. Students are responsible for making up any work missed due to absence. For courses that meet once a week, one unexcused absence will be penalised by a two percent deduction from the student s final course grade. For courses that meet two or more times a week, the same penalty will apply to two unexcused absences. Repeated absences in a course may result in failure. Faculty cannot excuse an absence. Requests for absences to be excused must be directed to the Academic Programs Coordinator. Students must provide appropriate documentation for their absence. In the case of illness, students must contact the Academic Programs Coordinator on the day of absence. They must provide medical documentation to Academic Programs Coordinator within three days of the absence in order to be medically excused. The note must include a medical judgement indicating that the student was unfit to attend Page 4 of 8

class/work on the specific day or dates of the absence. Faculty will be informed of excused absences by the Academic Programs staff. Classroom Expectations This is a seminar subject and requires the active participation of all students. It also requires engaged discussion, including listening to and respecting other points of view. Your behaviour in class should respect your classmates desire to learn. It is important for you to focus your full attention on the class, for the entire class period. Arrive to class on time. Once you are in class, you are expected to stay until class ends. Leaving to make or take phone calls, to meet with classmates, or to go to an interview, is not acceptable behaviour. Phones, digital music players, and any other communications or sound devices are not to be used during class. That means no phone calls, no texting, no social media, no email, and no internet browsing at any time during class. Laptop computers and tablets are not to be used during class except in rare instances for specific class-related activity expressly approved by your instructor. The only material you should be reading in class is material assigned for that class. Reading anything else, such as newspapers or magazines, or doing work from another class, is not acceptable. Class may not be recorded in any fashion audio, video, or otherwise without permission in writing from the instructor. Diversity, Inclusion and Equity NYU is committed to building a culture that respects and embraces diversity, inclusion, and equity, believing that these values in all their facets are, as President Andrew Hamilton has said, not only important to cherish for their own sake, but because they are also vital for advancing knowledge, sparking innovation, and creating sustainable communities. At NYU Sydney we are committed to creating a learning environment that: fosters intellectual inquiry, research, and artistic practices that respectfully and rigorously take account of a wide range of opinions, perspectives, and experiences; and promotes an inclusive community in which diversity is valued and every member feels they have a rightful place, is welcome and respected, and is supported in their endeavours. Religious Observance Students observing a religious holiday during regularly scheduled class time are entitled to miss class without any penalty to their grade. This is for the holiday only and does not include the days of travel that may come before and/or after the holiday. Students must notify their professor and the Academic Programs Coordinator in writing via email one week in advance before being absent for this purpose. Provisions to Students with disabilities who believe that they may need accommodations in a class are Page 5 of 8

students with Disabilities encouraged to contact the Moses Centre for Students with Disabilities at (212) 998-4980 as soon as possible to better ensure that such accommodations are implemented in a timely fashion. For more information, see Study Away and Disability. Required Texts It is a course expectation that you have done the required reading and have prepared sufficiently to discuss them in class. Custom NYU Lab Manual: From Genomes to Biomes (Provided by NYU Sydney) Other required equipment Lab book unlined paper Calculator Lab Coat and Safety Glasses Closed shoes Your Instructors Dr. Matthew C. Brandley (Ph.D., University of California Berkeley) is a Postdoctoral Fellow at the University of Sydney. Matthew studies the phylogenetics and morphological evolution of vertebrate animals, especially lizards and snakes. Matt also received his BS in 2001 (University of Oklahoma) and MS in 2005 (San Diego State University). Prior to moving to the University of Sydney, he completed a postdoctoral fellowship at the Department of Ecology and Evolutionary Biology at Yale University. He is particularly interested in how complex structures and unique body plans convergently evolve, and he studies these phenomena using a combination of genomic, gene expression, anatomical, and phylogenetic tools with data collected in the field or from museums. Matt also studies how predator-prey relationships affect the evolution of lizard and snake phenotypes and life history traits on the Japanese Izu Island Archipelago. He maintains international collaborations with research groups in China, India, Japan, Mexico, and the U.S. Matt is co-author of the textbook Herpetology 4th Edition (Sinauer Associates) published in 2015. Page 6 of 8

WEEKLY SCHEDULE (Labs) Week 1 Session Exper. Lab Topic Post lab Prac Quiz HW Due Writing Assignment Thu 2 Feb Week 2 Thu 9 Feb Week 3 Thu 16 Feb Week 4 Thu 23 Feb Week 5 Thu 2 Mar Week 6 Thu 9 Mar Week 8 Thu 23 Mar Week 9 Thu 30 Mar 1 2 3 Orientation and Safety in the Lab + Micropipetting MODULE 1: EVOLUTION The tree of life: Animal Phylogenetics (A) - - The tree of life: Animal Phylogenetics (B) 1 HW 1 Assigned Due Returned The tree of life: Animal Phylogenetics (C) 2 HW 2 Using RNAi and Point Mutations to Study Gene Expression (A) Using RNAi and Point Mutations to Study Gene Expression (B) MODULE 3: GENETICS AND GENE EXPRESSION 1 HW 3 3 HW4 Spring Break 13-17 March (Week 7) 2 Presentations: Your Tree of Life 4 HW 5 MODULE 2: MOLECULAR BIOLOGY 4 Genotype to Phenotype: PTC Analysis (A) 5 2 HW 6 Intro/ M&M Results/ Disc Final Writing Intro/ M&M Results/ Disc Intro/ M&M Results/ Disc Page 7 of 8

Session Exper. Lab Topic Post lab Prac Quiz HW Due Writing Assignment Assigned Due Returned Week 10 Thu 6 Apr Week 11 Thu 13 Apr 4 & 5 Genotype to Phenotype: PTC Analysis (B)/ PGio Transformation (A) Genotype to Phenotype: PTC Analysis (C)/ PGio Transformation (B) 6 HW 7 7 & 8 HW 8 Final Writing Final Writing MODULE 4: ENVIRONMENTAL BIOLOGY AND PLANT BIOLOGY Week 12 Thu 20 Apr Week 13 Thu 27 Apr 6 Plants 9 3 HW 9 7 Ecology 10 HW 10 Week 14 Thu 4 May Practical Final Exam Final Exam Page 8 of 8