How to Obtain Funding

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How to Obtain Funding b Other Organizational Grants ASE, AHA, ACC Julius M. Gardin, MD Professor and Chair Department of Medicine

Financial Disclosure Dr. Gardin has no conflicts of interest to disclose in connection with this presentation.

ASE Foundation Career Development Award* Award Type Duration Due Date Total $ ASE Foundation Career Development Award One year: June 2012 June 2013 February 15** $35,000 *One year awards **Additional 2012 funding opportunities will be available later this year.

American Society of Echocardiography Suggested Roadmap for Cardiovascular Ultrasound Research for the Future Potential Research Areas Global and regional LV function including speckle tracking and 3D technologies Molecular Imaging Selective targeting and retention of contrast at sites of disease Assess processes, e.g., protein expression, metabolic states, intracellular molecular trafficking, gene transcription, enzyme activity, ph, etc. Kaul, et al. J Am Soc Echo. 2011:24;455-464

American Society of Echocardiography Suggested Roadmap for Cardiovascular Ultrasound Research for the Future Potential Research Areas Therapeutic Ultrasound Sonothrombolysis: Ultrasound enhances activity of thrombolytic agents Gene and drug delivery High-intensity focused ultrasound: ablate uterine fibroids, prostate tumors, etc. Peripheral Arterial Disease Use of contrast-enhanced ultrasound Handheld ultrasound Kaul, et al. J Am Soc Echo. 2011:24;455-464

American Society of Echocardiography Suggested Roadmap for Cardiovascular Ultrasound Research for the Future Potential Research Areas Assessment of regional perfusion Microvascular disease Multicenter studies Future Technology-Related Issues Sensor technology: capable of fusion imaging and high-intensity focused ultrasound therapy Miniaturization: smaller (e.g., handheld), more powerful, capable of 2D and 3D echo Small animal imaging systems Kaul, et al. J Am Soc Echo. 2011:24;455-464

American Heart Association Research General scientific categories for classifying applications for research funding potentially related to echocardiography Bioengineering and Biotechnology Cardiac Biology Regulation Basic and Clinical/Translational Observational/Epidemiology Radiology and Imaging Basic Science/Clinical/Translational

American Heart Association Research Program Offerings and Career Stages Early Stages Making the Decision Gaining Credentials Directed Step Career Stage (Undergraduate student classified as junior or senior) (Doctoral Student) (Masters degree*, postdoctoral fellow) Program & Funding Component Undergraduate Student Research Program / Student Undergraduate Research Fellowship Predoctoral Fellowship Health Sciences Fellowship Medical Student Research Program Clinical Research Program Fellow-to-Faculty Transition Award Postdoctoral Fellowship *Healthcare professionals with a Masters degree, as well as healthcare professionals with certain doctoral degrees, may apply for the Clinical Research Program.

American Heart Association Research Program Offerings and Career Stages Middle and Later Stages Career Stage First Independent Step (Instructor, assistant professor or other first academic appointment or equivalent) Intermediate Level (Assistant professor, associate professor or equivalent) Recognized Investigator (Associate professor, professor or equivalent) Program & Funding Component Clinical Research Program Beginning Grantin-Aid Scientist Development Grant Grant-in-Aid** Innovative Research Grant Clinical Research Program Grant-in-Aid** Innovative Research Grant Established Investigator Award Grant-in-Aid** Innovative Research Grant **Applicants for the Grant-in-Aid award are expected to be independent investigators.

American Heart Association Research Award Types Award Type Career Stage Duration Total $ AHA Undergraduate Student Research Program / Student Undergraduate Research Fellowship Making the decision For student: 10 weeks minimum For institution: One or two years Maximum: $40,000 Medical Student Research Program Gaining credentials For student: 8, 10 or 12 weeks For institution: One year $4,800-7,200 Predoctoral Fellowship Gaining credentials One or two years $22-52,000 Health Sciences Fellowship Gaining credentials Two years $27,000 Clinical Research Program Fellow-to-Faculty Transition Award Directed step; First independent step; Intermediate level Two years $75-150,000 Directed step Five years $660,000 Total $ = Total amount of award funding

American Heart Association Research Award Types Award Type Career Stage Duration Total $ AHA Postdoctoral Fellowship Directed step Two years $78-112,136 Beginning Grant-In-Aid Grant-In-Aid Scientist Development Grant Innovative Research Grant Established Investigator Award First independent step (Instructor, assistant professor) First independent step; Intermediate level; Recognized investigator Two years $132-140,000 Two or three years $132-198,000 First independent step Three or four years $214,500-308,000 First independent step; Intermediate level; Recognized investigator Two years $150,000 Intermediate level Five years $400,000 Total $ = Total amount of award funding

American College of Cardiology Research Award Types Award Type Duration Due Date Total $ ACC Foundation ACCF Young Investigators Awards Competition ACCF/William F. Keating, Esq. Endowment Award for Hypertension and Peripheral Vascular Disease ACCF/Merck Research Fellowship Award ISCTR-ACCF CV Translational Research Award ACCF/Daiichi Sankyo Career Development Award One-time award October 15 $500-$2,000 One year: July 1 June 30 One year: July 1 June 30 One year: July 1 June 30 September 24 $70,000 September 24 $70,000 September 24 $70,000 Two years September 24 $140,000

INSTITUTE OF MEDICINE 100 Initial Priority Topics for Comparative Effectiveness Research Echo Related Compare effectiveness of diagnostic imaging performed by non-radiologists and radiologists. Compare effectiveness of traditional risk stratification for coronary heart disease (CHD) and noninvasive imaging (of coronary artery calcium, carotid intima media thickness, etc.) on CHD outcomes. Compare effectiveness of innovative treatment strategies (e.g., cardiac resynchronization, remote physiologic monitoring, pharmacologic treatment, novel agents such as CRF-2 receptors) for heart failure.