ARTEM V. DOMASHEVSKIY John Jay College of Criminal Justice, CUNY Phone: (646) 557-4640 Department of Sciences E-mail: adomashevskiy@jjay.cuny.edu 524 West 59 th Street, New York, NY 10019 Office: 05.66.25 NB /Lab: 05.65 NB PROFESSIONAL PREPARATION Hunter College, CUNY Chemistry B.A., 2006 Graduate Center, CUNY Biochemistry M.A., 2009 Graduate Center & Hunter College, CUNY Biochemistry Ph.D., 2011 John Jay College of Criminal Justice, CUNY Biochemistry & Biophysics 2011-2012 APPOINTMENTS 2012-present Assistant Professor, Biochemistry, John Jay College, CUNY 2011-12 Adjunct Assistant Professor, Biochemistry/General, John Jay College, CUNY 2011-12 Adjunct Assistant Professor, Biochemistry/Organic, Hunter College, CUNY 2012 Adjunct Assistant Professor, Bio-organic, New York Institute of Technology 2008-12 Substitute Lecturer, Full Time, Biochemistry/General, John Jay College, CUNY 2006-11 Adjunct Lecturer, Biochemistry/General, John Jay College, CUNY 2006-11 Adjunct Lecturer, Biochemistry/General/College Now, Hunter College, CUNY PUBLICATIONS (i) Peer Reviewed Domashevskiy, A.V., Das Darma, S., Goss, D.J., Cheng, S.Y. (2015) Binding and Enzymatic Studies of Pokeweed Antiviral Protein (PAP) and Tobacco Etch Virus (TEV) RNA Constructs. In preparation for resubmission to Biochim. Biophys. Acta. Domashevskiy, A.V., Goss, D.J. (2015) Pokeweed Antiviral Protein, a Ribosome Inactivating Protein: Activity, Inhibition and Prospects. Toxins 7, 274-298. Gunawardana, D., Domashevskiy, A.V., Gayler, K.R., Goss, D.J. (2015) Properties of mrnas containing a novel fluorescent analog: Anthranioyl-m 7 GpppG. Translation 3, e988538. Domashevskiy, A.V., Miyoshi, H., Goss, D.J. (2012) Inhibition of Pokeweed Antiviral Protein (PAP) by Turnip Mosaic Virus Genome-Linked Protein (VPg). J. Biol. Chem. 287, 29729-29738. Ray, S., Yumak, H., Domashevskiy, A., Gallie, D.R., Goss, D.J. (2006) Tobacco Etch Virus mrna Preferentially Binds Wheat Germ Eukaryotic Initiation Factor (eif)4g rather than (eif)iso4g. J. Biol. Chem. 281, 35826-35834. (ii) Abstracts Aitbakieva, V., Domashevskiy, A.V. Characterization of Pokeweed Antiviral Protein (PAP) Isoforms and Comparison of Their Enzymatic Activities toward Tobacco Etch Virus RNA. Experimental Biology: FASEB J. TBA, Boston, MA, April 2015. Rodriguez, D., Domashevskiy, A.V. Synthesis of Fluorescently-Labeled Tobacco Etch Virus (TEV) RNA and Its Interactions with Pokeweed Antiviral Protein. Experimental Biology: FASEB J. TBA, Boston, MA, April 2015. Williams, S., Domashevskiy, A.V. Pokeweed Antiviral Protein Binds to Structures Present in the 3 Untranslated Regions of Viral mrna, Annual Biomedical Research Conference for Minority Students, San Antonio, TX, November 2014. Page 1
Domashevskiy, A.V., Cheng, S.Y. Depurination of Tobacco Etch Virus (TEV) RNA by Pokeweed Antiviral Protein (PAP). American Society of Plant Biologists, Portland, OR, July 2014. Domashevskiy, A.V, Goss, D.J. An evolutionary arms race between plants and viruses. Experimental Biology: FASEB J. 28, 568.2, San Diego, CA, April 2014. Cheng, S.Y., Domashevskiy, A.V., Kobilinsky, L. The Effect of Eukaryotic Initiation Factors on the Activity of Pokeweed Antiviral Protein. Society of Toxicology, Phoenix, AZ, March 2014. Domashevskiy, A.V., Goss, D.J. Overcoming plant defense mechanisms. American Society of Plant Biologists, Providence, RI, July 2013. Domashevskiy, A.V., Goss, D.J. Inhibition of Pokeweed Antiviral Protein (PAP) by Turnip Mosaic Virus Genome-Linked Protein (VPg). Experimental Biology: FASEB J. 27, 539.1, Boston, MS, April 2013. Domashevskiy, A.V., Cheng, S.Y. Obligatory Structural Elements in Tobacco Etch Virus (TEV) RNA Required for Depurination by Pokeweed Antiviral Protein (PAP). Experimental Biology: FASEB J. 26, 773.1, San Diego, CA, April 2012. Domashevskiy, A.V., Goss, D.J., Cheng, S.Y. Viral Protein Inhibits Depurination of Pokeweed Antiviral Protein: Structural Elements in PAP & Tobacco Etch Virus (TEV) mrna Required for Depurination, New York Structural Biology Discussion Group, New York, NY, January 2012. Domashevskiy, A., Noro, K., Friedland, D.E., Goss, D.J., Cheng, S.Y. Turnip Mosaic Virus Genome-Linked Protein (VPg) Inhibits Pokeweed Antiviral Protein (PAP)-Mediated Depurination of RNA. MARM ACS J. 178, Maryland, MD, May 2011. Domashevskiy, A., Noro, K., Friedland, D.E., Goss, D.J. Inhibition of Pokeweed Antiviral Protein by Turnip Mosaic Virus. ACSYC Cooper Union, New York, NY, February 2011. Domashevskiy, A., Friedland, D.E., Goss, D.J. Effects of Viral Genome-Linked Protein on Depurination of Viral RNA by Pokeweed Antiviral Protein. FASEB J. 24, 499.3, Anaheim, CA, April 2010. Goss, D.J., Khan, M.A., Domashevskiy, A.V., Yumak, H. Biophysical Insights into the Mechanism of Viral Protein Synthesis. MARM ACS J., Queens, NY, May 2008. Ray, S., Domashevskiy, A., Yumak, H., Khan, M.A., Gallie, D.R., Goss, D.J. Tobacco Etch Virus mrna Preferentially Binds Wheat Germ Eukaryotic Initiation Factor (eif)4g rather than (eif)iso4g. FASEB J. 20, A108, San Francisco, CA, April 2006. (iii) Presentations (Abstracts listed above) Experimental Biology: American Society of Biochemistry and Molecular Biology (ASBMB) Annual Conference. Boston, MS, April 2015. Poster Presentations. Annual Biomedical Research Conference for Minority Students (ABRCMS). San Antonio, TX, November 2014. Poster American Society of Plant Biologists (ASPB) Annual Conference. Portland, OR, July 2014. Poster Annual Conference. San Diego, CA, April 2014. Poster Society of Toxicology (SOT) Annual Conference, Phoenix, AZ, March 2014. Poster American Society of Plant Biologists (ASPB) Annual Conference, Providence, RI, July 2013. Poster Page 2
Annual Conference, Boston, MS, April 2013. Poster Annual Conference, San-Diego, CA, April 2012. Poster New York Structural Biology Discussion Group (NYSBDG), 8 th Winter Meeting, New York, NY, January 2012. Poster American Chemical Society (ACS), 42 nd Annual Meeting, Maryland, MD, May 2011. Poster American Chemical Society Younger Chemists (ACSYC), Cooper Union, New York, NY, February 2011. Poster Annual Meeting, Anaheim, CA, April 2010. Poster American Chemical Society (ACS), 39 th Annual Meeting, Queens, NY, May 2008. Poster San Francisco, CA, April 2006. Poster (iv) Invited Talks Domashevskiy, A.V., PRISM Laboratory Tours for Perspective FOS Students, John Jay College, New York, NY, September 2014. Domashevskiy, A.V., Swenson, S. Forensic Science at John Jay College: Detailed Steps toward the Big Picture, Open House, John Jay College, New York, NY, November 2012-2014. Domashevskiy, A.V., Swenson, S. The Degree in B.S. FOS at John Jay College, Open House, John Jay College, New York, NY, November 2013. Domashevskiy, A.V. Protein Toxins: Ribosome Inactivating Proteins from Plants. Department of Science, John Jay College, New York, NY September 2012. Domashevskiy, A.V. Biochemistry of Drug Abuse. Town Hall Meeting, Dynamite Youth Foundation, Inc., Brooklyn, NY, June 2012. RESEARCH SUPPORT Program for Research Initiatives for Science Majors (PRISM) Equipment Grant (2015) Isothermal Titration Calorimeter (Nano ITC). John Jay College, CUNY. PI; Co-PIs: G. Zhang, S.Y. Cheng, E. Korobkova. Submitted; Pending. Program for Research Initiatives for Science Majors (PRISM) Equipment Grant (2015) Electroanalytic Station (Potentiostat). John Jay College, CUNY. Co-PI with G. Prini, Y. He; PI: G. Zhang. Submitted; Pending. CUNY Junior Faculty Research Award in Science and Engineering (JFRASE) (2015). Deciphering Plant Defense Systems: Anti-Viral Strategy of Pokeweed Plant. PI. Submitted; Pending. Professional Staff Congress (PSC), CUNY Research 46 th Award B (2015) Biophysical Studies of Liposomal Pokeweed Antiviral Protein for HIV Therapeutics. PI. Submitted; Pending. National Science Foundation (NSF) Research Opportunity Award (ROA) Supplement Opportunity (2014) Characterization of Eukaryotic Initiation Factor Interaction with mrna and mrna Analogs. Co-PI; PI: D.J. Goss. Awarded. Program for Research Initiatives for Science Majors (PRISM) Equipment Grant (2014). Geno/Grinder a high-throughput plant and tissue homogenizer. PI; Co-PIs: S.Y. Cheng, G. Proni. Awarded. Page 3
Professional Staff Congress (PSC), CUNY Research 44 th Award B (2013) Characterization of Enzymatic Mechanism of Pokeweed Antiviral Protein. PI. Awarded. Program for Research Initiatives for Science Majors (PRISM) Equipment Grant (2013) Circular Dichroism (CD) Spectrophotometer, John Jay College, CUNY. PI; Co-PI: G. Proni. Awarded. Departmental Travel Award (2013-2015) Awarded to present research findings at the Scientific Conferences. Experimental Biology: American Society of Biochemistry and Molecular Biology Travel Grant (2013-2014) Awarded to present research at the annual conference, Boston, MS and San Diego, CA. Start-up Award (2012-2014) Awarded by the Office of Provost, John Jay College, CUNY. CUNY Fellowship (2007-2011) Awarded by the Graduate Center, City University of New York in support of graduate work. Julianne B. Fusco Scholarship (2002-2011) Awarded by a private foundation (Dynamite Youth Foundation) to support undergraduate studies and research. CUNY Travel Grant (2008-2010) Awarded by the Graduate Center, City University of New York towards scientific conferences expenses. Science Fellowship (2006-2007) Awarded by Hunter College, Department of Chemistry in support of graduate studies and research. Helen S. Schectman Award (2006) Awarded by Hunter College, Department of Chemistry for excellence in undergraduate studies. SYNERGISTIC ACTIVITIES Course Development: - SCI TBA, Exploring Biotechnology, for Non-Science Majors, John Jay College, CUNY. TBA by UCASC for Fall 2015; - SCI 163, Extraordinary Chemistry of Ordinary Things, for Non-Science Majors. John Jay College, CUNY. Offered since Fall 2013. Course Coordination: - CHE 315, Biochemistry, Department of Sciences, John Jay College, CUNY; - SCI 163, Extraordinary Chemistry of Ordinary Things, Department of Sciences, John Jay College, CUNY. Book Chapter: - Encyclopedia of Molecular Biology, in collaboration with D. J. Goss (Hunter College) and J. Trujilo (Texas State University), Fall 2015 publication. Service: - University Faculty Senate (2014-2015); JJC Faculty Senate (2014-2015); JJC College Counsel (2014-2015); Departmental Curriculum Committee (2013-2014); MS FOS Curriculum Committee (2013-2014); MS FOS Outcomes Assessment Committee (2013-2014); Committee to hire a new Forensic Entomologist (2013-1014); Departmental Outcomes Assessment Committee (2013-2014); Self-evaluation of the FOS major committee (2013); Committee on Students Interests (2012-2013); Committee for the Development of Chemistry Major (2013); Committee to hire a new Chemistry candidate (2013). Reviewer: - National Science Foundation. Panel is TBA, 2013-2015; Professional Staff Congress (PSC)- CUNY, Biology Section, 2013-2015; Program Committee Member of the Forensic Science Criminalistics Research (FSCR), 2014; Journal of Nature and Science (JNSCI). Page 4
Judge: - New York City Science and Engineering Fair (NYCSEF), Biochemistry & Plant Biology, 2012-2015; - Experimental Biology: American Society of Biochemistry & Molecular Biology (ASBMB), Undergraduate Research Poster (2013-2015). Professional Membership: - American Society of Biochemistry and Molecular Biology, American Chemical Society, American Plant Biology Society, New York Academy of Sciences, The RNA Society, Biophysical Society; American Phytopathological Society. COLLABORATORS & OTHER AFFILIATIONS (i) Collaborators Dixie J. Goss, Department of Chemistry, Hunter College, New York; Vern Schramm, Department of Biochemistry, Albert Einstein College of Medicine, New York; Daniel R. Gallie, Department of Biochemistry, University of California, Riverside; Katheryn Hudak, York University, Toronto, Canada; Nilgun Tumer, Rutgers University, New York; Shu-Yuan Cheng, Gloria Proni, Elise and Champeil, Department of Sciences, John Jay College, New York; Evan Mintzer, Department of Chemistry, Yeshiva University, New York; Hiroshi Miyoshi, Mariana State University, Kawasaki, Japan; Karen Browning, Taxes State University, Texas; Minkui Luo, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York. (ii) Graduate and Postdoctoral Advisers Dixie J. Goss, Department of Chemistry, Hunter College; Diana E. Friedland, Department of Sciences, John Jay College; Shu-Yuan Cheng, Department of Sciences, John Jay College. (iii) Student Mentoring/Advising Eugene Gonzalez-Lopez (M.S., 2014 thesis co-adviser); Kristopher Kluge (M.S., 2013 thesis coadviser); Kristal Wilkins (M.S., 2013-present); Emmanuel Tieri (B.S., 2015-present); Sabrina De Los Santos (B.S., 2014-present); O jay Stewart (B.S., 2014-present); Valentina Aitbakieva (B.S., 2013-present); David Rodriguez (B.S., 2013-present); Samuel Reinfeld (B.S., 2013-present; accepted to New York Institute of Technology School of Osteopathic Medicine); Shawn Williams (B.S., 2013-present; accepted to Brown University); Zully Santiago (B.S., 2012-2014; winner of the undergraduate research 2014 PRISM poster competition; accepted to CUNY Graduate Program in Biochemistry); Thania Ramirez (B.S., 2012-2013, winner of the undergraduate research 2013 PRISM poster competition). Page 5