University of Florida Office: (352) 273-7868 Department of Pharmaceutics P4-31 1600 SW Archer Road JHMHC Gainesville, Florida 32610 E mail: palmieri@cop.ufl.edu SUMMARY Presently on the faculty at the University of Florida College of Pharmacy in the Department of Pharmaceutics. Author of over 80 publications and presentations on pharmaceutics, intellectual property, dosage forms, dissolutions, pharmacy education and the history of pharmacy. Has interacted extensively with USAN and WHO to obtain non-proprietary names for Pharmacia and Upjohn. Currently Chairman of the USAN Council. Consultant and Expert Witness on patent litigation involving dose forms, excipients, bioequivalence, and dissolution for numerous litigations. Expert witness before the Office of Generic Drugs. Twenty-five years of progressive responsibilities in an intellectual property management and technology transfer position coupled with fifteen years as a professor of pharmaceutics at major universities. Demonstrated and proven ability to set a vision, goals and direction of a department. Demonstrated leadership skills in a departmental and organizational setting. President of a national scientific academy and a major inter-fraternal organization including setting a vision and goals for these organizations during a critical growth period. Successfully led projects across management lines where reporting relationships were often difficult to establish, no precedent existed and the use of creative problem solving and communication skills were necessary. UNIVERSITY OF FLORIDA PROFESSIONAL EXPERIENCE Assistant Scholar of Pharmaceutics 2011 present Responsibilities include instructing graduate and undergraduate students in clinical biochemistry, dose form design, sustained release and dissolution. Graduate Student Coordinator for Pharmaceutics and member of Graduate Studies Committee. Member of numerous research committees for graduate students Curator, College of Pharmacy Museum
Page 2 of 14 Clinical Assistant Professor of Pharmaceutics 2006-2011 Responsibilities include instructing graduate and undergraduate students in clinical biochemistry, dose form design, sustained release and dissolution. Graduate Student Coordinator for Pharmaceutics and member of Graduate Studies Committee. Member of numerous research committees for graduate students Curator, College of Pharmacy Museum Assistant Director, Office Technology Licensing 2000-2006 Adjunct Professor of Pharmaceutics Interacting with faculty in the College of Pharmacy, College of Medicine, Chemistry Department and others on a daily basis to discuss experiments, experimental design and evaluation of results. Evaluating the University s intellectual property portfolio in the life sciences and providing assistance in the protection and marketing of this intellectual property. Negotiating and drafting license agreements, option agreements, stock agreements, materials transfer agreements, confidential disclosure agreements and/or providing guidance and oversight in the drafting of such agreements. Coordinating licensing activities with the intake of new invention disclosures and with the patent prosecution of new disclosures. Managing the University s active licenses and contractual obligations in the assigned areas in the life sciences. PHARMACIA & UPJOHN, Kalamazoo, Michigan Manager, Technology Protection 1996-2000 Daily interactions with dose form scientists assisting in evaluation of various dosage forms. Managed three Ph.D. professionals responsible for providing accurate, critically evaluated, concise, strategic patent information concerning company and competitor patents. Evaluated commercial potential of inventions, and educated the scientific community on intellectual property issues. Assisted in determining patentability of inventions from a scientific standpoint. Made decisions and recommendations on filing worldwide patents, USAN names, INN names. Reviewed publications prior to release outside of the company. Evaluated competitor patented compounds and technologies as potential acquisitions. Also evaluated patents considered for in-licensing and served on numerous corporate committees such as the US patent committee, the US Trademark Committee and various process improvement teams. Copyright transfer agent. Manager, Technology Protection and Tracking 1994 1996 Manager, Intellectual Property and Research Contracts 1992 1994
Page 3 of 14 Responsibilities included patent decisions, manuscript review, negotiation of scientific and monetary terms for research and scientific collaborations between Upjohn, other companies, academia and government agencies. Manager, Intellectual Property, The Upjohn Company 1988 1992 Senior Patent Liaison Scientist, The Upjohn Company 1984 1988 THE UNIVERSITY OF WYOMING, LARAMIE, WYOMING 1975 1984 Associate Professor of Pharmaceutics (Tenured) 1980-1984 Assistant Professor of Pharmaceutics 1975-1980 TEACHING RESPONSIBILITIES Dose Form Design Pharmacy Seminar Calculations Physical Pharmacy Biopharmaceutics and Pharmacokinetics Problems in Pharmacy Dissolution Member of numerous PhD students research committees ADMINISTRATIVE EXPERIENCE Graduate Student Coordinator, Pharmaceutics Department (2009-present) Graduate Studies Committee (2008-present) College of Pharmacy Admissions Committee, University of Florida (2008-present) Curator, College of Pharmacy Museum (2008-present) Led major review of College of Pharmacy Graduate Programs (2008-2009) Chair Contributed Papers Section, AIHP (2004-2006) Chair APRS Basic Pharmaceutics Section, APRS (2004-2005) Chair-elect APRS Basic Pharmaceutics Section, APRS (2002-2004) Chair-elect, Contributed Papers Section, Am. Inst. History of Pharmacy. (2002-2004) Councilor, American Institute History of Pharmacy (2002-2004) International Officer, Kappa Psi Pharmaceutical Fraternity (1999-2007) Member at-large Basic Pharmaceutics Section, APRS (1999-2001) Plainwell School Board: Vice President and Treasurer (1998-1999) President, Academy of Pharmaceutical Research and Sciences (1990) Councilor, American Institute for the History of Pharmacy (1991-1993) Chairman-Elect, Academy of Pharmaceutical Research and Science (1989) Member, Industrial Advisory Board, University of Rhode Island (1990-2000) Member, Industrial Advisory Board, Creighton University (1991-2000) Chairman, Basic Pharmaceutical Sciences Section APRS-APhA (1988) President, College Fraternity Editors Association (1988-1989) President-elect, College Fraternity Editors Association (1987-1988)
Page 4 of 14 Secretary, College Fraternity Editors Association (1986-1987) Treasurer, College Fraternity Editors Association (1985-1986) Member of the Board of Directors, College Fraternity Editors Association (1983-1990) Secretary, Faculty Senate, University of Wyoming (1982-1983) Editor, The Mask of Kappa Psi, a quarterly magazine, circulation 15,000 (1980-1984) Member of various university committees such as the Vice-President for Finance Search Committee, Research Coordination, Health Sciences College Review, University Development, Promotion and Tenure. Chairman of University of Wyoming Graduate School Committee. MEMBERSHIP IN PROFESSIONAL SOCIETIES Academy of Pharmaceutical Research and College Fraternity Editors Science Association American Association of Pharmaceutical American Institute of the History of Scientists Pharmacy American Pharmaceutical Association Kappa Psi Pharmaceutical Fraternity Sigma Xi Rho Chi American Association of Colleges of Pharmacy NATIONAL PROFESSIONAL SERVICE USAN Council, Chair 2009-12 (2003-2012) Chair, Special Interest Group, History of Pharmacy, AACP (2012-present) Secretary, Pharmaceutics Section, American Association of Colleges (2011-present) of Pharmacy Editorial Advisory Board, Journal of the American Pharmacist (2011-present) Association Editorial Advisory Board, Journal of Chemical and Pharmaceutical (2009-present) Sciences Editorial Advisory Board, Research Journal of Pharmaceutical (2008-present) Biological and Chemical Sciences Reviewer for a variety of scientific journals (1980-present) APhA Handbook of Pharmaceutical Excipients, 2 nd, 4 th & 5 th Edition, Steering Committee Chairman APhA Handbook of Pharmaceutical Excipients 3 rd ed., Laboratory Chairman APhA Scientific Affairs Reference Committee Chairman (1992) Kappa Psi Pharmaceutical Fraternity, various national committees (1980 -present) APhA Scientific Affairs Policy Committee Chairman (1990) APRS Policy Committee, Chairman (1989-1990) APRS Policy Committee, Vice-Chairman (1988) APhA Policy Advisory Committee (1988)
Page 5 of 14 APhA Reference Committee on Scientific Affairs, Chairman (1988) APRS Policy Committee, Vice-Chairman (1988) AIHP Committee on Membership (1987-1990) AAPS Professional Affairs Committee (1986-1987) APhA Policy Committee on Educational Affairs (1986-1987) APS Professional Affairs Committee (1985-1986) APS Committee on Public Affairs (1984) CFEA Membership Committee, Chairman (1984) College Fraternity Editors Long-Range Planning Committee (1982-1984) AIHP Committee on Nominations (1983) APS Committee on Resolutions (1983) AIHP Committee on Preservation of Sources, Chairman (1981-1983) AACP Council of Sections Administrative Board, Representative from the Pharmaceutics Sections (1981-1983) APS Monograph Committee for the Handbook of Pharmaceutical Excipients (1977-1983) Academy of Pharmaceutical Sciences Dissolution Methodology Committee (1977) PROFESSIONAL RECOGNITION AND AWARDS A. Richard Bliss Award presented by Kappa Psi Pharmaceutical Fraternity for sustained Contributions to the Profession (2012) Teacher of the Year Finalist (2011) Fellow, APhA Academy of Pharmaceutical Sciences (1994) Editor Emeritus, THE MASK of Kappa Psi (1994) College Fraternity Editor's Association, Ford Award for outstanding service (1994) University of Rhode Island, College of Pharmacy Leadership Award (1990) Adjunct Professor, Creighton University School of Pharmacy (1991-1999) PMA Faculty Fellow (1978) Lederle Pharmacy Faculty Award (1977) University of Wyoming Faculty Professional Growth Award (1977) Bristol Award (1971) PHARMACIST LICENSURE Rhode Island Georgia EDUCATION University of Rhode Island, B.S. Pharmacy University of Rhode Island, M.S. Pharmacy
Page 6 of 14 University of Georgia, Ph.D. Pharmaceutics
Page 7 of 14 RESEARCH INTERESTS Dose Form Design Dissolution Pharmaceutical Patents Microencapsulation and Other Sustained Release Delivery Systems Drug Release from Suppositories History of Pharmacy Development of Student Experiments for the Laboratory Development and Evaluation of Student Admission Methods Industrial Academic Interactions CONTINUING EDUCATION Covey Seven Habits of Highly Effective People Training Career Development Workshop Assertiveness Training Problem-Solving and Decision-Making Perceptive Management Pharmacology Review Coaching, Counseling, Communications and Conflict Management Communications and Problem-Solving GRANTS Summer Research Fellowship, The University of Wyoming, 1976. Sandoz Research Grant Dissolution of Suppositories, 1982. Various travel grants to attend national and international meetings. REFEREED PUBLICATIONS 1. Palmieri, A., Intellectual Property and the Pharmaceutical Scientist - A View from the Other Side, AM. J. PHARM. ED., 53:353-355 (1989). 2. Palmieri, A., Dissolution of Suppositories V: Effect of Aging on Aspirin Release from Polyethylene Suppositories with and without Crospovidone, DRUG DEV. IND. PHARM., 12:1477 (1986). 3. Palmieri, A., Dissolution of Suppositories IV: Effect of Povidone on Aspirin Release from PEG Bases, DRUG DEV. IND. PHARM., 10:137 (1984). 4. Palmieri, A., John C. Davis, Sr., Portrait of a Rocky Mountain Drug Wholesaling Pioneer,
Page 8 of 14 ANNALS OF WYOMING, 55(2): 33 Fall (1983). 5. Palmieri, A., Dissolution of Suppositories III: Effect of Povidone on Acetaminophen Release from PEG Suppositories, DRUG DEV. IND. PHARM., 421 (1983). 6. Palmieri, A., Dissolution of Suppositories and Acetaminophen Release, PHARMACEUTICAL TECHNOLOGY, 6(6): 70 (1982). 7. Palmieri, A. and Humberson, C., Medical Incidents in the Life of Dr. John H. Finfrock, ANAL OF WYOMING, 53(2): 64 Fall 1981. 8. Palmieri, A., Suppository Dissolution Testing: Apparatus Design and Release of Aspirin, DRUG DEV. IND. PHARM., 7:247 (1981). 9. Palmieri, A., A Review of Oxidative Stability of Pharmaceutically Important Compounds, ASIAN J. PHARM. SCI., 2:3 (1980). 10. Palmieri, A., Microencapsulation and Dissolution Parameters of Undecenovanillylamide - A Potential Coyote Deterrent, J. PHARM. SCI., 68:1561 (1979). 11. Palmieri, A., Multivariate Prediction of Academic Success of Transfer Students II: Evaluation of the Predictor Equations, AM. J. PHARM. ED., 43:110 (1979). 12. Palmieri, A., An Undergraduate Experiment in Biopharmaceuticals: The Serum and Urine Assay of Ampicillin Generics, AM. J. PHARM. ED., 43:21 (1979). 13. Palmieri, A., Drug Therapy at a Frontier Fort Hospital, PHARMACY IN HISTORY, 21:31 (1979). 14. Palmieri, A., Effect of Dissolved Oxygen Levels on the Oxidative Degradation of Pyrogallol, J. PHARM. SCI. 67:1338 (1978). 15. Palmieri, A., Dissolution of Prednisone Microcapsules in Conditions Simulating the ph of the GI Tract, CAN. J. PHARM. SCI., 12:88 (1977). 16. Palmieri, A., Production of a Coacervate Film for Microcapsule Diffusion Studies, DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 3:309 (1977). 17. Palmieri, A., A Model for Multivariate Prediction of Academic Success of Transfer Studies in Pharmacy School, AM. J. PHARM. ED., 41:264 (1977). 18. Palmieri, A., Lausier, J.M. and Paruta, A.N., Utilization of Deaeration Via Gas Permeation and Oxidative Stabilization of Pyrogallol, DRUG DEVELOPMENT COMMUNICATIONS, 2:171 (1976).
Page 9 of 14 19. Palmieri, A. and Sternson, L.A., A Student Experiment in Biopharmaceutics: The Effect on the Enzymatic Oxidation of Xanthine by Xanthine Oxidase, AM. J. PHARM. ED., 38:541 (1974). BOOKS AND CHAPTERS IN BOOKS 1. Pharmaceutical Coatings, Edible Films and Coatings for Food and Other Applications, Chapter 12: Overview of Pharmaceutical Coatings Elizabeth A. Baldwin, Ed. CRC Press, 2012 2. Dissolution Theory, Methodology and Testing. Editor and contributor, Dissolution Technologies, 2007. 3. Numerous Monographs for the Handbook of Pharmaceutical Excipients. 1980-present. 4. Voices, A History of the College Fraternity Editors Association, 1998 5. Thirty Years of Scientific Excellence: the American Pharmaceutical Association Academy of Pharmaceutical Research and Science, 1965-1995. APhA (1996). 6. Handbook of Pharmaceutical Excipients, Am. Pharm. Assoc., Chairman US Steering Committee, (1994). 7. Palmieri, A., Introduction to Pharmacokinetics, Pharmat, Inc. - A Continuing Education Course for Pharmacists, Vol. VIII, #16. This course has been updated and formatted for use on the IBM- PC (1986). 8. Palmieri, A. and Luzzi, L.A., "Pharmaceutical Applications of Microcapsules", Chapter 1 in Biomedical Applications of Microcapsules, F. Lim, ed., CRC Text (1984). 9. Palmieri, A., "Wyoming" in the Dictionary of American Medical Biography, M. Kaufman, ed., Greenwood Press (1984). 10. Palmieri, A. and Price, J.C., Microencapsulation: New Techniques and Applications, Chapter 8, "Microencapsulation of Drugs Suspended in Oil, Preparation and Evaluation of Prednisone and Hydrocortisone Microcapsules", T. Kondo, ed., Techno, Inc. (1979). PRESENTATIONS 1. Palmieri, A., Academic Industrial Interactions. Presented at major conferences, Universities and pharmacy schools. 2. Palmieri A., Opportunities for Collaboration Between Academics and Industry. How to Improve
Page 10 of 14 Your Chances of Funding, AAPS, November, 1995. 3. Palmieri, A., The Challenges Posed by Mergers and Acquisitions in the Pharmaceutical Industry, An Industrial Perspective, AACP Meeting of Chairs, November 1995. 4. Palmieri, A., Kalamazoo Celery Patent Medicines, American Institute for the History of Pharmacy, March 1995. 5. Palmieri, A. Patents and Inventions, American Chemical Society Great Lakes and Central Joint Meeting, June 1994. 6. Palmieri, A., A Comparison of Ayer's Almanacs, 1880-1894, Am. Institute of the History of Pharmacy, March 1, 1994. 7. Palmieri, A., Academic Industrial Interactions, APRS, March 1994. 8. Palmieri, A., Patent Considerations in Material Transfer Agreement, American Society of Pharmacy Law, Dallas, TX, March 1993. 9. Palmieri, A., Patents and the Industrial-Academic Interface, University of Rhode Island, October 1992, Duquesne 1995, Creighton 1993. 10. Palmieri, A., Industry-Academic Interactions, Vanderbilt University, August 1992. University of Georgia, 1993. 11. Palmieri, A., Biotechnology Drug Development, Distinguished lecturer, Society of Sigma Xi, University of Tennessee, Memphis, May 1992. 12. Palmieri, A., Patents, University of Tennessee, Memphis TN, May 1992. 13. Palmieri, A., Emerging Trends in Biotechnology Drug Development, Sanford University, October 1991. 14. Palmieri, A., Dose Form Patents; presented to Upjohn Drug Delivery Worldwide Conference, Sept 1991. 15. Palmieri, A., Transformation of the Pharmaceutical Sciences, 1941-1991, a symposium, American Institute for the History of Pharmacy, New Orleans, March 11, 1991. 16. Palmieri, A., Biotechnology Rationing - A Scientific Perspective, Seminar-by-the-Sea, Newport, RI, February 28, 1991. 17. Palmieri, A., Conference moderator, Globalization of Pharmaceuticals, Washington, DC, Sept. 13-14, 1990.
Page 11 of 14 18. Palmieri, A., Biotechnology, Scientific Considerations for the Pharmacist, University of Wyoming Continuing Education, August 1990. 19. Palmieri, A., Material Transfer Agreements, Statement of Investigator Forms, PMA-NIH Meeting, Washington, D.C., March 1990. 20. Palmieri, A., Intellectual Property and the Pharmaceutical Scientist - One Traitors Perspective. Symposium at the Am. Assoc. of Colleges of Pharmacy, Portland, Oregon, July 9, 1989. 21. Palmieri, A., Intellectual Property in Industry, Duquesne University, March 1989. 22. Palmieri, A., Seminar on Patents and Publications, Control Division of Upjohn, November 7, 1986. 23. Palmieri, A., Seminar on Patents in the Pharmaceutical Sciences, Duquesne University School of Pharmacy, October 1986. 24. Palmieri, A., Influence of Aging on Aspirin Release from PEG Suppositories with and without Crospovidone, APS, Montreal, 1984. 25. Palmieri, A., The Hamlin Wizard Oil Songbook - An Example of Early Twentieth Century Advertising, AIHP, Montreal, 1984. 26. Palmieri, A., John C. Davis, Sr.: Portrait of a Rocky Mountain Drug Wholesaling Pioneer, 1901-1909, AIHP, New Orleans, 1983. 27. Palmieri, A., Dissolution of Suppositories IV: Effect of Crospovidone on Aspirin Release from PEG Bases, APS, New Orleans, 1983. 28. Palmieri, A., Dissolution from Suppositories, Fifteenth Annual Industrial Pharmacy Conference, Madison, Wisconsin, 1982. 29. Palmieri, A., Patent Medicine Advertising, Annual Meeting of the Wyoming Pharmaceutical Association, Cheyenne, WY, 1982. 30. Palmieri, A., Dissolution of Suppositories III: Effect of Crospovidone on Acetaminophen Release, APS Meeting, Las Vegas, 1982. 31. Palmieri, A. and Humberson, C., An Early Wyoming Ranch Medicine Kit, AIHP Meeting, Las Vegas, 1982. 32. Palmieri, A., Dissolution of Suppositories II: Acetaminophen Release from PEG Bases and Commercially Available Bases, APS Meeting, St. Louis, MO, 1981.
Page 12 of 14 33. Palmieri, A. and Humberson, C., Dr. John H. Finfrock, Laramie's First Physician and Druggist, AIHP, St. Louis, MO, 1981. 34. Palmieri, A. and Hunter, R., A Student Experiment in Biopharmaceutics - Ampicillin, American Association of Colleges of Pharmacy, Boston, 1980. 35. Palmieri, A., Suppository Dissolution Testing I: Apparatus Design and Validation, APS Meeting, Washington, D.C., 1980. 36. Palmieri, A. and Ballek, J., Health Care in Pioneer Wyoming, AIHP, Washington, D.C. 1980. 37. Palmieri, A., Early Wyoming Medicine, Laramie Westerners, 1979. 38. Palmieri, A., Comparison of Urban and Rural Drug Information Centers: Utilization and Personnel, Academy of Pharmacy Practice, Anaheim, CA, 1979. 39. Palmieri, A., Frontier Medicine, Laramie County Historical Society, 1979. 40. Palmieri, A., Microencapsulation and Dissolution Parameters of Undecenovanillyamide - A Potential Coyote Deterrent, APS Meeting, 1979. 41. Palmieri, A., A Frontier Fort Hospital: Fort Laramie, Wyoming Territory, 1870-1889, AIHP Annual Meeting, Montreal, 1978. 42. Palmieri, A., Effect of Dissolved Oxygen Levels on the Oxidative Degradation of Pyrogallol, APS Meeting, Phoenix, AZ, 1977. 43. Palmieri, A., Dissolution of Prednisone Microcapsules in Conditions, Simulating The ph of the GI Tract, APhA-APS Meeting, NY, 1977. 44. Palmieri, A., A Model for Multivariate Prediction of Academic Success of Transfer Students in Pharmacy Schools, Annual Meeting of District 7, NABP-AACP, Casper, WY, 1976. 45. Harelik, J., Palmieri, A. and Scalley, R., A Model for the Development Computer Assisted Random Selection of Students for Clerkship Placement AACP Annual Meeting, Minneapolis, MN, 1976. 46. Palmieri, A. and Price, J.C., Microencapsulation of Drugs Suspended in Oil, Third International Symposium on Microencapsulation, Tokyo, 1976. JOURNAL AND BOOK REVIEWS Reviewed manuscripts for J. Pharm. Sci., and Am. J. Pharm. Ed., J. Pharm. Research. Reviewer for The Handbook of Nonprescription Drugs, published by APhA.
Page 13 of 14 Textbooks Reviewed for Am. J. Pharm. Ed.: a) "The Hydrophobic Effect" by C. Tanford, AM. J. PHARM. ED., 44:318. b) "Sustained and Controlled Release Drug Delivery Systems" by J.R. Robinson, AM. J. PHARM. ED., 43:165. c) "Microencapsulation and Related Drug Processes" by P.F. Darcy, AM. J. PHARM. ED., 48:455. d) "Validation of Aseptic Pharmaceutical Processes" by Carleton and Agalloco, AM. J. PHARM. ED. e) "Remington's Pharmaceutical Sciences", AM. J. PHARM. ED. OTHER PUBLICATIONS 1. Palmieri, A., My heros have always been pharmacists, American Pharmacy (Leadership Forum), Vol. NS30, No. 6, p. 64, June 1990. 2. Palmieri, A., Globalization, It's a small world after all..., APRS Academy Report, Vol. 27, No. 1, April 1990. 3. Palmieri, A., Professional Status and Shortages, American Pharmacy (Leadership Forum), Vol. NS29, #10, p. 54, Oct. 1989. 4. Palmieri, A., 21st Century Drug Development: Many Questions, Few Answers, Academy Reporter, Vol. 26, #2, June 1989. 5. Palmieri, A., Analytical Pharmaceutical Chemistry (letter to the editor), AM. J. PHARM. ED., 48:92, 1984. 6. Palmieri, A., Wasting Space on Conversion Tables, AMERICAN PHARMACY, NS22, 9 p. 5 September 1982. 7. Palmieri, A., There are No Pills Anymore, (letter to the editor), HOSPITAL PHARMACY, 16:627, 1981. 8. Palmieri, A., Equivalent Drugs, Home Economics Extension Journal, University of Wyoming, March 1979. 9. Palmieri, A., The FDA - Protector or Violator of Consumer Rights, Home Economics Extension Journal, University of Wyoming, July 1977. 10. Palmieri, A., Comment on Dr. Clinical Series, (letter to the editor), DRUG INTELLIGENCE AND CLINICAL PHARMACY, 10:656, 1976. 11. Palmieri, A., Drug Substitution, Home Economics Extension Journal, University of Wyoming, June 1976.
Page 14 of 14 12. Palmieri, A., Pharmaceutical Preparations, Wyoming Drug Information Newsletter,Vol. 1, Winter 1976.