Dr. Stacy Brown (Maiden name: Stacy Cross) Assistant Professor of Chemistry stacy.brown@citadel.edu 101 Hopper Drive 171 Moultrie Street Summerville, SC 29483 The Citadel, Department of Chemistry Phone: (843) 486-0752 Charleston, SC 29409 Phone: (843) 953-7791 Education Doctor of Philosophy (Ph.D.) (08/98-08/02) Department of Pharmaceutical and Biomedical Sciences College of Pharmacy The University of Georgia Graduate Research Advisor: Dr. Michael G. Bartlett GPA: 3.78 Dissertation title: I. TRACE LEVEL DETERMINATION OF TRICHLOROETHYLENE FROM LIVER, LUNG, AND KIDNEY TISSUES BY GAS CHROMATOGRAPHY/MASS SPECTROMETRY II. HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC ANALYSIS AND COMPARATIVE PHARMACOKINETICS OF ACYCLOVIR AND ACYCLOVIR/ZIDOVUDINE THERAPIES IN THE PREGNANT RAT B.S. Chemistry (08/94-05/98) The University of Tennessee at Chattanooga Graduated Magna Cum Laude, Honors in Chemistry Undergraduate Research Advisor: Dr. Thomas G. Waddell GPA: 3.83 Research Interests Development of novel Solid-Phase Microextraction (SPME) methods to be coupled with Gas Chromatography-Mass Spectrometry (GC-MS) Examination of the prevalence of jet-fuel derived hydrocarbons in the environment Development of SPME-GC-MS and GC-MS methods of the detection and quantification of marker hydrocarbons for jet fuel contamination in environmental matrices Development of chromatographic methods for separation of drugs of abuse from biological matrices
Teaching Experience The Citadel: o Instrumental Methods, CHEM 302 Instructor and Lab Coordinator Spring 2004 o Introductory Chemistry II, CHEM 104 Instructor - Spring 2003, Spring 2004 o Introductory Chemistry II Lab, CHEM 114 Instructor - Spring 2003, Spring 2004 o Introductory Chemistry I, CHEM 103 Instructor - Fall 2002, Summer 2003, Fall 2003 o Introductory Chemistry I Lab, CHEM 113 Instructor - Fall 2002, Summer 2003, Fall 2003 The University of Georgia: o Pharmacy Skills Labs, PHRM 3100, PHRM 3110, PHRM 4120, PHRM 4130 Teaching Assistant - Spring 1999, Fall 2000, Spring 2000, Fall 2001, Spring 2001, Spring 2002 o General Biology Labs, BIOL 1103, BIOL 1104 Instructor - Fall 1999, Spring 2000 o Clinical Pharmacokinetics, PHRM 5260 Teaching Assistant - Fall 2000 o Biochemistry, PHRM 3050 Teaching Assistant - Fall 2001 The University of Tennessee at Chattanooga: o College Algebra, MATH 105, MATH 106 Teaching Assistant & Student Instructor - Fall 1994, Spring 1995, Fall 1995, Spring 1996, Fall 1996, Spring 1997 Professional and Academic Affiliations Citadel Academy for the Scholarship of Teaching, Learning, and Evaluation (CASTLE) 09/02-present American Association of Pharmaceutical Scientists (AAPS) 09/98-01/03 American Chemical Society (ACS) 05/98-present American Society of Mass Spectrometry (ASMS) 01/99-present
Publications 1. Bishop J.C., Cross S.D., and Waddell T.G. Prebiotic Transamination. Origins of Life and Evolution of the Biosphere. 27 (4) 319-324, 1997. 2. S. Brown, C.A. White, C.K. Chu, and M.G. Bartlett, Determination of Acyclovir in Maternal Plasma, Amnitoic Fluid, Fetal, and Placental Tissue by High Performance Liquid Chromatography. The Journal of Chromatography B. 772 (2) 327-334, 2002. 3. S. Brown, C.A. White, and M.G. Bartlett, Hydrophilic Interaction Liquid Chromatography Electrospray Mass Spectrometry Determination of Acyclovir in Pregnant Rat Plasma and Tissues. Rapid Communications in Mass Spectrometry. 16 (19) 1871-1876, 2002. 4. S. Brown, C.A. White, and M.G. Bartlett, High Performance Liquid Chromatographic (HPLC) Determination of Acyclovir and Zidovudine in Maternal Plasma, Amniotic Fluid, Fetal and Placental Tissue using Ultra-Violet (UV) Detection. The Journal of Liquid Chromatography and Related Technologies. 25 (18) 2857-2871, 2002. 5. S. Brown, J.V. Bruckner, S. Muralidhara, and M.G. Bartlett, Trace Level Determination of Trichloroethylene in Rat Plasma, Lung, Liver, and Kidney Tissue by Gas Chromatography Magnetic Sector Mass Spectrometry. The Journal of Chromatography B. 783 (2) 319-325, 2003. 6. S. Brown, A.M. Dixon, J.V. Bruckner, and M.G. Bartlett, A Validated GC-MS Assay for the Quantitation of Trichloroethylene (TCE) From Drinking Water. The International Journal of Environmental Analytical Chemistry. 83 (5) 427-432, 2003. 7. S. Brown, C.A. White, C.K. Chu, and M.G. Bartlett, Pharmacokinetics of Intravenous Acyclovir, Zidovudine, and Acyclovir-Zidovudine in Pregnant Rats. Antimicrobial Agents and Chemotherapy. 47 (3) 991-996, 2003. 8. S. Brown, S. Lewis, A.T. Eley, C.A. White, and M.G. Bartlett, Dose-Dependant Pharmacokinetics of Zidovudine (AZT) in the Pregnant Rat, manuscript in preparation. Posters and Presentations 1. S. Cross, J.V. Bruckner, S. Muralidhara, and M.G. Bartlett Trace Level Detection of Trichloroethylene and its Metabolites from Whole Blood 2 nd Annual Athens-Atlanta MS Discussion Group Summer Symposium Athens, GA, July 1999 2. S. Cross, J.V.Bruckner, S. Muralidhara, and M.G. Bartlett Trace Level Detection of Trichloroethylene and its Metabolites Departmental Seminar College of Pharmacy, Department of Pharmaceutical and Biomedical Sciences The University of Georgia Athens, GA, October 1999 3. S. Cross, J.V. Bruckner, S. Muralidhara, and M.G. Bartlett Trace Level Detection of Trichloroethylene and its Metabolites from Whole Blood 27 th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting
New Orleans, LA, May 2000 4. S. Cross, J.V. Bruckner, S. Muralidhara, and M.G. Bartlett Trace Level Detection of Trichloroethylene and its Metabolites from Whole Blood 48 th Annual Meeting of the American Society of Mass Spectrometry Long Beach, CA, June 2000 5. S. Brown, J.V. Bruckner, S. Muralidhara, and M.G. Bartlett Trace Level Determination of Trichloroethylene from Blood and Affected Tissues Guest Seminar Speaker Department of Chemistry The University of Tennessee at Chattanooga Chattanooga, TN, November 2000 6. S. Brown, C.A.White, C.K. Chu, and M.G. Bartlett Determination of Acyclovir for Study in the Pregnant Rat Model Departmental Seminar College of Pharmacy, Department of Pharmaceutical and Biomedical Sciences The University of Georgia Athens, GA, February 2001 7. S. Brown, J.V. Bruckner, S. Muralidhara, and M.G. Bartlett Determination of Trichloroethylene from Drinking Water and Selected Tissues 49 th Annual Meeting of the American Society of Mass Spectrometry Chicago, IL, May 2001 8. S. Brown, C.A.White, C.K. Chu, and M.G. Bartlett Determination of Acyclovir from Plasma, Amniotic Fluid, Placenta, and Fetal Tissue for Study in the Pregnant Rat Model 15 th Annual Meeting of the American Association of Pharmaceutical Scientists Denver, CO, October 2001 9. S. Brown, C.A.White, C.K. Chu, and M.G. Bartlett Determination of Acyclovir from Plasma, Amniotic Fluid, Placenta, and Fetal Tissue for Study in the Pregnant Rat Model 15 th Annual Meeting of the American Association of Pharmaceutical Scientists Denver, CO, October 2001 10. A.M. Dixon, S. Brown, S. Muralidhara, M.G. Bartlett, and J.V. Bruckner Sensitive Methods for Trace Level Determination of Trichloroethylene in Rat Plasma 41 st Annual Meeting of the Society of Toxicology Nashville, TN, March 2002 11. S. Brown, C.A.White, C.K. Chu, and M.G. Bartlett An LC-MS-MS Study of Acyclovir in the Pregnant Rat: Determination of Acyclovir from Plasma, Amniotic Fluid, Placenta, and Fetal Tissue 50 th Annual Meeting of the American Society of Mass Spectrometry Orlando, FL, June 2002 12. A.M. Dixon, S. Brown, S. Muralidhara, M.G. Bartlett, and J.V. Bruckner Sensitive Methods for Trace Level Determination of Trichloroethylene in Rat Tissues 50 th Annual Meeting of the American Society of Mass Spectrometry Orlando, FL, June 2002 13. S. Brown, C.A. White, and M.G. Bartlett Pharmacokientics and Placental Transfer of Acyclovir and Zidovudine Therapies in the Pregnant Rat
16 th Annual Meeting of the American Association of Pharmaceutical Scientists Toronto, Canada, November 2002 14. S. Brown, C.A. White, and M.G. Bartlett A Study of Acyclovir in the Pregnant Rat: LC-MS-MS Analysis of Acyclovir From Maternal Plasma, Amniotic Fluid, Placenta, and Fetal Tissue 54 th Southeast Regional Meeting of the American Chemical Society Charleston, SC, November 2002 15. C.A. White, S.D. Brown, A.T. Eley, and M.G. Bartlett Non-Linear Distribution of AZT in the Pregnant Rat 17 th Annual Meeting of the American Association of Pharmaceutical Scientists Salt Lake City, UT, October 2003 Research Support Bioanalysis of Controlled Substances by SPME-GC-MS Stacy Brown (PI) The Citadel Foundation - $4500 01/03-06/04 Graduate School Awards Northeast Georgia Chapter of the ACS Chemistry Student of the Year (04/02) Winner of the Celltech Pharmaceuticals Analysis and Pharmaceutical Quality travel award for the 2001 AAPS meeting 1999-2000 UGA Teaching Assistant of the Year Award Member of the Rho Chi Pharmacy Honor Society (04/02-present) Recipient of Department of Pharmaceutical and Biomedical Sciences graduate research fellowship (1998-1999, 1999-2000, 2000-20001, 2001-2002 school years) University and Community Service Citadel Library Committee: Member (09/03-present) Citadel Computer Services Committee: Member (09/03-present); Sub-committee chairperson for new faculty computer acquisition (09/03-present) Citadel Chemistry Facilities Committee: Chair (08/03-present) Citadel Chemistry Extracurricular Activities Committee: Chair (08/02-08/03) Citadel Chemistry Assessment & Advisement Committee: Member (08/02-present) Citadel Chemistry Introductory Chemistry Committee: Member (08/02-present) UGA Graduate Education Committee: Student representative (01/99-08/01)
UGA student chapter of AAPS (UGA-AAPS): Active member (09/98-08/02); Treasurer of UGA-AAPS (01/00-09/00), President of UGA-AAPS (09/00-09/01) UGA Academic Honesty Court: Hearing Panelist (09/99-08/02); Founding member of the Integrity Task Force (ITF) Academic Honesty Education team (03/01-08/02) Graduate Research Association of Students in Pharmacy (GRASP): Planning Committee for the 2002 Annual Meeting (05/01-05/02) Georgia Science & Engineering Fair: Volunteer judge (04/00-04/02) Athens Canine Rescue: Active volunteer (05/99-08/02); Volunteer Coordinator (01/01-08/02) Employment Experience Assistant Professor of Chemistry, The Citadel (09/02-present) Graduate Research Assistant, UGA Mass Spectrometry Bioanalytical Lab (10/98-08/02) Quality Control Chemist (GLP/cGMP Laboratory), Noramco (05/00-10/01) Teaching Assistant, UGA Department of Pharmaceutical and Biomedical Sciences and UGA Division of Biological Sciences (01/99 08/02) Environmental Research Intern for Tennessee Department of Environment and Conservation, Division of Water Supply (05/97-09/97) Mathematics Tutor and Student Instructor, UT- Chattanooga (08/94-05/97) Pharmacy Technician, Piney Flats Drug Center, Piney Flats, TN (05/95-08/96)