Case-Based Inpatient Pediatric Dermatology

Case-Based Inpatient Pediatric Dermatology

Marcia Hogeling Editor Case-Based Inpatient Pediatric Dermatology

Editor Marcia Hogeling Director of Pediatric Dermatology UCLA Division of Dermatology Los Angeles, CA, USA ISBN 978-3-319-31567-6 ISBN 978-3-319-31569-0 (ebook) DOI 10.1007/978-3-319-31569-0 Library of Congress Control Number: 2016939391 Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland

For Yaron

Preface Case-based inpatient pediatric dermatology is an approach to pediatric skin disease specific to hospitalized children. The idea for the book initially came from doing a talk on interesting inpatient dermatology cases and realizing there was no specific resource book for this niche of pediatric dermatology. Skin problems make up to one third of patient complaints, and although dermatology is primarily an outpatient specialty, there are specific cutaneous diseases that are more commonly seen in hospitalized children. The book is geared as a reference toward a diverse audience including hospitalists, emergency and inpatient clinicians, pediatricians, dermatologists, residents, and medical students. The book is organized into a question-and-answer format that should make it more interactive and helpful for those that are studying for exams and to learn specific teaching pearls. There are 14 chapters with associated images to provide you clinical examples. To make this book possible, I have been blessed by the help from many brilliant and generous colleagues from across the country and overseas, who have contributed their time and expertise to writing chapters. I thank them for their great efforts in creating this book. Thanks to Connie Walsh, developmental editor, for her invaluable assistance. I also thank my mentors, who have taught me academic pediatric dermatology, and my patients, who are a daily inspiration. I hope that you will find this book to be a valuable resource and guide. Los Angeles, CA, USA Marcia Hogeling vii

Contents 1 Atopic Dermatitis and Papulosquamous Disorders... 1 Sarah Asch and Megha M. Tollefson 2 Viral Infections... 19 Patrick McMahon and Robert James Smith 3 Bacterial Infections... 35 Catalina Matiz and Emily Osier 4 Fungal Infections in the Pediatric Age Group... 53 Luluah Al-Mubarak, Colleen Cotton, and Sheila Fallon Friedlander 5 Drug Eruptions and Hypersensitivity Syndromes... 69 Nicole N. Harter and Minnelly Luu 6 Acute and Chronic Graft-Versus-Host Disease of the Skin... 101 Hasan Khosravi, Anar Mikailov, and Jennifer T. Huang 7 Autoimmune Skin Disorders (Collagen Vascular)... 119 Clayton Sontheimer and Heather A. Brandling-Bennett 8 Inpatient Neonatal Dermatology... 131 Kimberly Jablon and Erin Mathes 9 Neoplastic and Infiltrative Diseases... 147 Ellen S. Haddock and Wynnis L. Tom 10 Vascular Anomalies... 173 Sheilagh M. Maguiness and Christina L. Boull 11 Abuse and Factitious Disorders... 191 Kirsten Simonton and Kara N. Shah 12 Bullous Disorders of Childhood... 205 Marion E. Tamesis and Kimberly D. Morel ix

x Contents 13 Vasculitis... 221 Marcia Hogeling 14 Skin Signs of Systemic Diseases... 229 Adam Bartlett, Pamela Palasanthiran, Marcia Hogeling, and Orli Wargon Index... 241

Contributors Luluah Al-Mubarak, MD Department of Dermatology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia Sarah Asch, MD Department of Dermatology, Mayo Clinic, Rochester, MN, USA Adam Bartlett, BSc, MBBS, MPHTM Department of Immunology and Infectious Diseases, Sydney Children s Hospital, Randwick, NSW, Australia Christina L. Boull, MD Department of Pediatric Dermatology, University of Minnesota, Minneapolis, MN, USA Heather A. Brandling-Bennett, MD Division of Dermatology, Department of Pediatrics, Seattle Children s Hospital/University of Washington, Seattle, WA, USA Colleen Cotton, MD Division of Dermatology, Department of Medicine, University of Arizona, Tucson, AZ, USA Sheila Fallon Friedlander, MD Department of Dermatology and Pediatrics, University of California San Diego School of Medicine/Rady Children s Hospital, San Diego, CA, USA Ellen S. Haddock, MBA. Department of Pediatric and Adolescent Dermatology, University of California, San Diego, CA, USA Nicole N. Harter, BS, MD Department of Dermatology, Children s Hospital Los Angeles, Keck School of Medicine of USC, Los Angeles, CA, USA Marcia Hogeling, MD Division of Dermatology, University of California, Los Angeles, Los Angeles, CA, USA Jennifer T. Huang, MD Dermatology Program, Boston Children s Hospital, Harvard Medical School, Boston, MA, USA Kimberly Jablon, MD Department of Pediatrics, UCSF Benioff Childrens Hospital, San Francisco, CA, USA xi

xii Contributors Hasan Khosravi, BS Harvard Medical School, Boston, MA, USA Minnelly Luu, MD Department of Dermatology, Children s Hospital Los Angeles, Keck School of Medicine of USC, Los Angeles, CA, USA Sheilagh M. Maguiness, MD Department of Pediatric Dermatology, University of Minnesota, Minneapolis, MN, USA Erin Mathes, MD Department of Dermatology and Pediatrics, University of California, San Francisco, San Francisco, CA, USA Catalina Matiz, MD Division of Pediatric and Adolescent Dermatology, University of California, San Diego, CA, USA Division of Pediatric and Adolescent Dermatology, Department of Dermatology, Rady Children s Hospital, San Diego, CA, USA Patrick McMahon, MD Department of Pediatric Dermatology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Anar Mikailov, MD Harvard Combined Medicine-Dermatology Residency Program, Boston, MA, USA Kimberly D. Morel, MD, FAAD, FAAP Department of Dermatology and Pediatrics, Morgan Stanley Children s Hospital of New York-Presbyterian/ Columbia University, New York, NY, USA Emily Osier, MD Division of Pediatric and Adolescent Dermatology, Department of Dermatology, University of California, San Diego, CA, USA Division of Pediatric and Adolescent Dermatology, Department of Dermatology, Rady Children s Hospital, San Diego, CA, USA Pamela Palasanthiran, MBBS, MD, FRACP Department of Immunology and Infectious Diseases, Sydney Children s Hospital, Randwick, NSW, Australia Kara N. Shah, MD, PhD Division of Dermatology, Cincinnati Children s Hospital, Cincinnati, OH, USA Kirsten Simonton, MD Mayerson Center for Safe and Healthy Children, Cincinnati Children s Hospital, Cincinnati, OH, USA Robert James Smith, BS Department of Pediatric Dermatology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Clayton Sontheimer, MD Division of Rheumatology, Department of Pediatrics, Seattle Children s Hospital/University of Washington, Seattle, WA, USA

Contributors xiii Marion E. Tamesis, MD Department of Dermatology, New York Presbyterian Hospital, Columbia University Medical Center, New York, NY, USA Megha M. Tollefson, MD Department of Dermatology and Pediatrics, Mayo Clinic, Rochester, MN, USA Wynnis L. Tom, MD Department of Dermatology and Pediatrics, University of California, San Diego and Rady Children s Hospital, San Diego, CA, USA Orli Wargon, MBBS (Hons1), MClinEd, FACD Department Pediatric Dermatology, Sydney Children s Hospital, Randwick, NSW, Australia