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Author: Michael Jibson, M.D., Ph.D., 2009 License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution Share Alike 3.0 License: http://creativecommons.org/licenses/by-sa/3.0/ We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize your ability to use, share, and adapt it. The citation key on the following slide provides information about how you may share and adapt this material. Copyright holders of content included in this material should contact open.michigan@umich.edu with any questions, corrections, or clarification regarding the use of content. For more information about how to cite these materials visit http://open.umich.edu/education/about/terms-of-use. Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosis or a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Please speak to your physician if you have questions about your medical condition. Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers.

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M2 Psychiatry Sequence Michael Jibson Fall 2008

Cluster B Personality Disorders Antisocial Personality Disorder A pattern of disregard for, and violation of, the rights of others. (DSM-IV)

American Psychiatric Association: Diagnostic and Manual of Mental Disorders, 4 th ed, Text Revision (DSM-IV-TR)

Clinical Vignettes

Antisocial Personality Disorder Prevalence: 3% of males and 1% of females Sex ratio: M:F=3:1 Comorbidity: Substance abuse, attention deficit disorder, depression, anxiety Family: Somatization disorder, substance abuse, Cluster B disorders, esp. antisocial personality disorder

Major Clinical Issues Violence Criminal behavior Suicide

Treatment Antisocial Personality Disorder Psychotherapy - Not generally useful, although it may alleviate depression and anxiety, especially if the patient is immobilized (e.g., in jail) Medication - May be useful for comorbid disorders; uncontrolled rage may be helped somewhat by antipsychotics or mood stabilizers

Physician-patient Interaction Firm limits are essential Substance abuse is a major problem complicated by genuine distress and incessant manipulation

Additional Source Information for more information see: http://open.umich.edu/wiki/citationpolicy Slide 5: American Psychiatric Association: Diagnostic and Manual of Mental Disorders, 4 th ed, Text Revision (DSM-IV-TR), Washington, DC, American Psychiatric Association, 2000, p. 706