International Course NEUROENDOCRINE TUMORS FINAL PROGRAM

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1 FINAL PROGRAM

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3 International Course NEUROENDOCRINE TUMORS FINAL PROGRAM

4 INDEX Welcome Message...3 List of Speakers, Chairs & Tutors...4 Program at a Glance...5 Scientific Program...6 General Information...9 Transfer Schedule...9 Social Program...10 Registration...10 Course Organizer...10 Acknowledgements page 2

5 «stay small but perform with distinction» WELCOME MESSAGE Neuroendocrine Tumors: A Comprehensive Course to Guide the Diagnosis and Management This course is designed as an educational tool as well as a practical manual for the diagnosis of patients with suspected neuroendocrine tumors and a variety of associated disorders, guiding the physician to long-term follow-up. Conceptually, this course is more than a list of lectures. It provides a step-by-step approach to diagnosis, to appropriate and dynamic challenge tests and to contemporary more efficient therapeutic management. The accretion of knowledge and its particular applications in the workshops have highly placed this course from theory to the forefront of medical practice. We have witnessed the phenomenon over the years of the transformation of research-oriented procedures becoming useful, routine, and critical determining factors in the diagnosis and management of certain neuroendocrine tumors and related endocrinopathies. Clinical and laboratory discipline is a dynamic science, and it must be assisted by ensuing talented scientists in the specific disciplines it serves. Consequently, a debt of gratitude is owed to each one of the distinguished tutors and speakers, who are embarking on their scientific topics and are serving our ultimate targets, education and clinical practice! Therefore, from heart thanks to their synergistic confluence that has given birth to this unique interactive course with my true appreciation to our financial supporters who have helped it to make steady steps forward Undoubtedly, my high esteem is owed to each member of the organizing committee who has provided tirelessly their input on every step of the efforts to achieve and maintain high scientific and social standards of the course. Thus, we have arrived at 2 nd COMBO with a certain degree of pride, but with a greater degree of responsibility to every participant, whose presence in this course consolidates our commitment and dedication to teach and practice evidence based medicine! Yours Evanthia Diamanti-Kandarakis, MD, PhD President of the Course, Professor of Medicine-Endocrinology & Metabolism Medical School of Athens, Greece 3

6 LIST OF SPEAKERS, CHAIRS & TUTORS Goran Akerstrom Professor Emeritus, Past President of the International Society of Surgery (ISS), Sweden John Buscombe MBBS, MD, FRCP, FRCR: Clinical Lead and Consultant in the Department of Nuclear Medicine, Cambridge University Hospital, UK Sofi Chatzioannou Associate Professor of Neuclear Medicine, Director of PET/CT, FBRAA, Athens, Greece Joseph Davar MD, PhD, FRCP, FACC, Consultant Cardiologist & Hon. Senior Lecturer (UCL), UK Evanthia Diamanti-Kandarakis MD, PhD, Professor of Medicine Endocrinology & Metabolism Medical School University of Athens Greece Nicola Fazio Director, Unit of Gastrointestinal and Neuroendocrine Tumors, European Institute of Oncology, IEO, Milano, Italy Hara Gakiopoulou Assistant Professor, First Department of Pathology, Medical School University of Athens, Greece Dimitrios Goulis Associate Professor of Endocrinology, Medical School, Aristotle University of Thessaloniki, Greece Filippos Kaldrimidis Internist - Endocrinologist, Director of Endocrinology Department «METAXA» Cancer Hospital, Piraeus, Greece Gregory Kaltsas Associate Professor Internal Medicine-Endocrinology Medical School University of Athens, Greece 4 Dimitrios Kountouras MD, PhD, Internist - Hepatologist, «MHTERA» Hospital Athens, Greece Massimo Milione MD, PhD, Dirigente medico I Livello, Dipartimento di Patologia Diagnostica e Laboratorio, Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy George C. Nikou MD, PhD, Consultant, Section of Neuroendocrine Tumors, 3rd Department of Internal Medicine, Medical School University of Athens, Sotiria Hospital, Athens, Greece Kjell Oberg Professor of Endocrine Oncology at the Medical Faculty of Uppsala University, Sweden Ulrich-Frank Pape Dr. med, Specialist in internal medicine and gastroenterology, emergency medicine, Ltd. Senior Physician, Medical Clinic M. S. Hepatology and Gastroenterology, Charité, Campus Mitte, University Medicine, Berlin, Germany Marianne Pavel Prof. Internistin, Endokrinologin, Diabetologin DDG Schwerpunkt Neuroendokrine Tumore, Charité, Campus Mitte, University Medicine Berlin, Germany Kaliopi Pazaitou Head of Department Endocrinology- Endocrine Oncology, Theagenio Cancer Hospital, Thessaloniki, Greece John Ramage MD, FRCP, Consultant Physician in Gastroenterology and Hepatology, North Hampshire Hospital, Basingstoke, UK and Lead for Neuroendocrine Tumour Service, Kings College Hospital, London, UK Kostas Syrigos Professor of Internal Medicine - Oncology, Head of the 3rd Department of Medicine, Medical School University of Athens, Greece Christos Toumpanakis MD, PhD, FRCP, Consultant in Gastroenterology & Neuroendocrine Tumours Honorary Senior Lecturer UCL, UK Sophia Tseleni Professor of Pathology, Medical School University of Athens, Greece Marinella Tzanela Consultant Endocrinologist Evangelismos Hospital Athens, Greece Staffan Welin Consultant at Department of Medical Sciences, Endocrin Oncology - Uppsala University, Sweden Dominic Yu Consultant Radiologist, Royal Free London NHS Foundation Trust, UK Nikolaos Ziras MD, PhD, Medical Oncologist, Director and Head Medical Oncology Department «METAXA» Cancer Hospital, Piraeus, Greece George Zografos Professor and Chairman, 1st Department of Propedeutic Surgery, Medical School University of Athens, Greece

7 PROGRAM AT A GLANCE 08:30-09:00 1 st October nd October rd October th October :00-10:00 SESSION II: SESSION IV: Clinical picture and Non medical 10:00-11:00 Staging treatment 11:00-11:30 Coffee Break 11:30-12:00 Coffee Break SESSION VI: From present to future 12:00-12:30 12:30-13:00 SESSION V: Combo Clinical cases by the experts Closure & Farewell 13:00-13:30 SESSION III: Medical treatment 13:30-14:00 Group Photography 14:00-14:30 14:30-15:00 15:00-15:30 15:30-16:00 16:00-16:30 16:30-17:00 17:00-17:30 17:30-17:45 17:45-18:00 18:00-18:30 18:30-19:00 19:00-19:30 19:30-20:00 20:00-20:15 REGISTRATION Opening of the Course Self-introduction by participants SESSION I: Epidemiology & Pathology 20:15-20:30 Welcome Lunch Break Tutorial 1 for participants: Short cases Lunch Break Tutorial 2 for participants: Long cases 5

8 SCIENTIFIC PROGRAM 1 st OCTOBER :00-17:30 REGISTRATION 17:30-17:45 OPENING OF THE COURSE E. Diamanti-Kandarakis (Greece) 17:45-18:00 SELF-INTRODUCTION BY PARTICIPANTS 18:00-20:15 SESSION I: EPIDEMIOLOGY AND PATHOLOGY Chairing: E. Diamanti-Kandarakis (Greece), G. Kaltsas (Greece) 18:00-18:30 NETs: EPIDEMIOLOGY, SYMPTOMS AND DIFFERENTIAL Speaker: K. Oberg (Sweden) 18:30-19:00 HISTOLOGY AND CLASSIFICATION OF NETs Speaker: M. Milione (Italy) 19:00-19:30 CYTOLOGY OF NETS Speaker: S. Tseleni (Greece) 19:30-20:00 WHICH ARE THE BEST MARKERS FOR NET DIAGNOSIS AND FOLLOW-UP? Speaker: G. Kaltsas (Greece) 20:00-20:15 DISCUSSION 20:15-20:30 WELCOME E. Diamanti-Kandarakis & the Metropolitan Bishop of Thebes and Levadia Georgios 20:30 DINNER AT THE MONASTERY-CONFERENCE CENTER 6 2 nd OCTOBER :30-11:30 SESSION II: CLINICAL PICTURE AND STAGING Chairing: S. Chatzioannou (Greece), K. Oberg (Sweeden) 08:30-09:00 FUNCTIONING AND NON FUNCTIONING GEP NETs Speaker: S. Welin (Sweden) 09:00-09:30 NON-GEP PRIMARY NETs Speaker: K. Syrigos (Greece) 09:30-10:00 ASSOCIATED SYNDROMES Chairing: J. Ramage (UK) 10:00-10:30 CARCINOID HEART DISEASE Speaker: J. Davar (UK) 10:30-11:00 IMAGING: WHICH ARE THE TOOLS AND THEIR ROLE IN PRIMARY AND METASTASTATIC NETs Speaker: S. Chatzioannou (Greece) 11: DISCUSSION 11:30-12:00 COFFEE BREAK 12:00-14:30 SESSION III: MEDICAL TREATMENT Chairing: M. Tzanela (Greece), S. Welin (Sweden)

9 12:00-12:30 ROLE OF SOMATOSTATIN ANALOGUES IN FUNCTIONING AND NON-FUNCTIONING NETs Speaker: S. Welin (Sweden) 12:30-13:00 TARGET THERAPY: WHAT THE EVIDENCE SHOWS Speaker: K. Oberg (Sweden) 13:00-13:30 OLD AND NEW CHEMOTHERAPY FOR NETs Speaker: Ch. Toumpanakis (UK) 13:30-14:00 EFFECTS OF NET MEDICAL TREATMENT ON LIPID AND GLUCOSE METABOLISM Speaker: K. Pazaitou (Greece) 14:00-14:30 DISCUSSION 14:30-16:30 LUNCH 17:00-19:00 TUTORIAL 1 FOR PARTICIPANTS: SHORT CASES Tutors: Ch. Toumpanakis (UK), G. Kaltsas (Greece), M. Pavel (Germany), D. Kountouras (Greece), U-F. Pape (Germany), D. Goulis (Greece), M. Tzanela (Greece) 20:00 DINNER AT THE MUSSES VALLEY 3 rd OCTOBER :00-11:00 SESSION IV: NON MEDICAL TREATMENT Chairing: N. Ziras (Greece), F. Kaldrimidis (Greece) 09:00-09:30 NUCLEAR MEDICINE: PRRT Speaker: J. Buscombe (UK) 09:30-10:00 INTERVENTIONAL RADIOLOGY: LOCOREGIONAL TREATMENT Speaker: D. Yu (UK) 10:00-10:30 PNETs OR NON PNETs: ROLE OF SURGERY Speaker: G. Akerstrom (Sweden) 10:30-11:00 DISCUSSION 11:00-11:30 COFFEE BREAK 11:30-13:30 SESSION V: COMBO CLINICAL CASES BY THE EXPERTS Chairing: G. Nikou (Greece), G. Akerstrom (Sweden) 11:30-12:30 CASE 1: LUNG NET Speaker: G. Kaltsas (Greece), H. Gakiopoulou (Greece) 12:30-13:30 CASE 2: GEP NET Speaker: N. Fazio (Italy), M. Milione (Italy) 13:30-14:00 GROUP PHOTOGRAPHY 14:00-16:00 LUNCH 16:30-19:30 TUTORIAL 2 FOR PARTICIPANTS: LONG CASES Tutors: Ch. Toumpanakis (UK), G. Kaltsas (Greece), M. Pavel (Germany), D. Kountouras (Greece), U-F. Pape (Germany), D. Goulis (Greece), M. Tzanela (Greece) 20:00 TRADITIONAL DINNER: DANCING UNDER THE STARS 7

10 4 th OCTOBER :00-12:30 SESSION VI: FROM PRESENT TO FUTURE Chairing: G. Zografos (Greece), N. Fazio (Italy) 10:00-10:30 TRANSLATION OF MOLECULAR PATHWAYS INTO CLINICAL TRIALS Speaker: M. Pavel (Germany) 10:30-11:00 FUTURE IMAGING Speaker: J. Buscombe (UK) 11:00-11:30 MULTIDISCIPLINARY APPROACH FOR THE TREATMENT OF NETs Speaker: U.-F. Pape (Germany) 11:30-12:00 NET PATIENTS AND THEIR QUALITY OF LIFE Speaker: J. Ramage (UK) 12:00-12:30 DISCUSSION 12:30-13:00 CLOSURE AND FAREWELL E. Diamanti-Kandarakis (Greece) 3rd COMBO ENDO Course: SEE YOU IN SEPTEMBER 2015!! 8

11 GENERAL INFORMATION Conference Center: Conference Center of Evangelistria Monastery, Evangelistria Aliartou Viotias, Greece The Conference Center is located in the heart of the massif of the mountain of the Musses and Hesiod, Mount Helicon, at an altitude of 650 meters, one of the nicest areas of Viotia, surrounded by an oak forest and, higher up the slopes, by forests of fir. The proximity to the Holy Annunciation Monastery complements the natural environment with another spiritual environment, the Orthodox Tradition. The Monastery of Evangelistria, built in the 12th Century A.D. and renovated in 1656, played a historical role during the Ottoman period and World War II, by offering its Crypt, accessed right under the Holy Altar. Since 1959, Evangelistria has been a women s monastery and hosts a textile workshop. Surrounded by a landscape of unique natural beauty, it offers a magnificent view of the area downhill. There is a large lecture hall and designated areas for group work during workshops. Language: The official language of the Course is English. No official translation will be provided Slide Center Preview Room: The Speaker s Center Preview Room is located at the foyer of the main hall. The speakers are requested to hand in the final version of their presentation at least one hour prior to their scheduled Session. Badges: Name badges and relevant material will be provided on site to all registered participants. All delegates are requested to wear their name badge during the course. Certificates of Attendance: All registered delegates are entitled a Certificate of Attendance. Certificates can be collected on October 4 th Emergencies: Whilst in Greece, European Union citizens may seek any help they might need (police, ambulance, fire brigade, cost guard) by ringing from anywhere in Greece the number 112. The number is answered by English-speaking staff, and can be dialed from public telephones or mobile telephones. TRANSFER SCHEDULE From the Athens International Airport to the Conference Center From the hotels (Philippos & Erato) to the Conference Center From the Conference Center to the Hotels (Philippos & Erato) October 1 st From the Conference Center and the hotels (Philippos & Erato) to the restaurant From the restaurant to the Conference Center & the Hotels October 2 nd : October 3rd After Midnight From the Conference Center to the Athens International Airport October 4th

12 SOCIAL PROGRAM* 20:30, Wednesday, October 1, 2014 Dinner at the Monastery-Conference Center 20:00, Thursday, October 2, 2014 Dinner at the Musses Valley 20:00, Friday, October 3, 2014 The traditional Dinner: Dancing under the stars *All Participants are invited REGISTRATIONS Full Registration fee for early career/young trainees/fellows: 530 (from September 6th until October 1st 2014) The Registration fee includes: Attendance to Lectures Full course material Active Participation to workshops Workshop Material Coffee Breaks Lunch Breaks Accommodation at the Conference Center of Evangelistria Monastery for 3 nights* Registration fee for more experienced scientists/specialists: 250 (until 1st October 2014) The Registration fee includes: Attendance to Lectures only Coffee Breaks Lunch Breaks Course Organizer FREI S.A. Travel - Congress 3 Paparigopoulou Street, Athens, Greece Tel: , Fax: , E-mai: info@frei.gr Web: 10

13 ACKNOWLEDGEMENTS We extend our appreciation to the following companies for their support 11

14 12 NOTES

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