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1 Clinical Pharmaceutics and Pharmacokinetics I Lecture and Projects 2 credits Class 1 Spring and Fall semesters Timetable Friday 17:15-20: Seminar room, Main Building, Faculty Pharm. Sci., Tsushima campus Yuji Kurosaki (Pressor, Department Pharmaceutical Formulation Design, Graduate School Medicine, Dentistry and Pharmaceutical Sciences) Tetsuya Aiba (Associate Pressor, Department Clinical Pharmacokinetics, Graduate School Medicine, Dentistry and Pharmaceutical Sciences) 1. To understand scientific backgrounds necessary for pharmaceutical dosage design, i.e., physical pharmaceutics, biopharmaceutics and pharmacokinetics 2. To conduct literature searches in pharmaceutical dosage design 3. To discuss journal articles by scientific rationality Develop an ability to discuss the scientific backgrounds the pharmaceutical dosage design including selection dosage forms, development new dosage forms, and the adjustment daily dose to specific patients. pharmaceutics, biopharmaceutics and pharmacokinetics including introductory lectures and seminars with mutual discussions in several topics in the latest journal reports will be served. laboratory. 1-2 Introductive lecture dosage form design relating to physical pharmacy and clinical needs 3-15 Case studies pharmaceutical dosage design reported in journals in seminar style (Student must present topics relating to one s own major at least 3 times.) Evaluation Relation to Evaluated by the depth understanding in lecturer and by performance discussion Pr. Kurosaki and Assoc. Pr. Aiba in their research.

2 Clinical Pharmaceutics and Pharmacokinetics I Projects and Practicals 4 credits Class 1 Spring and Fall semesters Timetable Monday-Friday (not designated) Pharm. Sci., Tsushima campus Yuji Kurosaki (Pressor, Department Pharmaceutical Formulation Design, Graduate School Medicine, Dentistry and Pharmaceutical Sciences) Tetsuya Aiba (Associate Pressor, Department Clinical Pharmacokinetics, Graduate School Medicine, Dentistry and Pharmaceutical Sciences) 1. To plan one s research in a strategic and rational ways based on scientific backgrounds, i.e., physical pharmaceutics, biopharmaceutics and pharmacokinetics 2. To conduct literature searches relating to one s research 3. To discuss one s research results with scientific rationality Develop an ability to discuss one s research plan and its results with scientific rationality based on physical pharmaceutics, biopharmaceutics and pharmacokinetics. Discussion with lecturer in planning one s research must be performed. Student complete exercises and experiments one s research in the lab through this subject. Preparation for the presentation one s new findings in a certain academic meeting will be included. Practices (15 classes) Practices in pharmacokinetics and application to one s research Exercises (45 classes) Exercises to discuss the findings in research including case studies pharmaceutical dosage design reported in journals in seminar style Preparation for the presentation one s new findings Evaluation Evaluated by performance practices and exercises to prepare one s presentation Pr. Kurosaki and Assoc. Pr. Aiba in their research.

3 Clinical Pharmaceutics and Pharmacokinetics II Lecture and Projects 2 credits Class 2 Spring and Fall semesters Timetable Friday 17:15-20: Seminar room, Main Building, Faculty Pharm. Sci., Tsushima campus Yuji Kurosaki (Pressor, Department Pharmaceutical Formulation Design, Graduate School Medicine, Dentistry and Pharmaceutical Sciences) Tetsuya Aiba (Associate Pressor, Department Clinical Pharmacokinetics, Graduate School Medicine, Dentistry and Pharmaceutical Sciences) 1. To present the conducted journal articles rationality 2. To be well-understood scientific backgrounds necessary for pharmaceutical dosage design, i.e., physical pharmaceutics, biopharmaceutics and pharmacokinetics 3. To discuss journal articles with one s research rationally Grow in capability one s research presentation referring related journal articles. A small class-course focused on pharmacokinetic analysis in developing new pharmaceutical dosage design exhibiting new functions including introductory lectures and seminars with mutual discussions in several topics in the latest journal reports will be served. laboratory. 1-2 Introductive lecture pharmacokinetic analysis relating to biopharmaceutic and clinical researches 3-15 Case studies pharmacokinetic studies reported in journals in seminar style (Student must present topics relating to one s own major at least 3 times.) Evaluation Relation to Evaluated by the depth understanding in lecturer and by performance presentation and discussion Pr. Kurosaki and Assoc. Pr. Aiba in their research.

4 Clinical Pharmaceutics and Pharmacokinetics II Projects and Practicals 4 credits Class 2 Spring and Fall semesters Timetable Monday-Friday (not designated) Pharm. Sci., Tsushima campus Yuji Kurosaki (Pressor, Department Pharmaceutical Formulation Design, Graduate School Medicine, Dentistry and Pharmaceutical Sciences) Tetsuya Aiba (Associate Pressor, Department Clinical Pharmacokinetics, Graduate School Medicine, Dentistry and Pharmaceutical Sciences) 1. To plan one s research in a strategic and rational ways based on scientific backgrounds, i.e., physical pharmaceutics, biopharmaceutics and pharmacokinetics (Advanced) 2. To conduct literature searches relating to one s research (Advanced) 3. To discuss one s research results with scientific rationality (Advanced) Develop an ability to discuss one s research plan and its results with scientific rationality based on physical pharmaceutics, biopharmaceutics and pharmacokinetics. (Advanced) Discussion with lecturer in planning one s research must be performed. Student complete exercises and experiments one s research in the lab through this subject. Preparation for the presentation one s new findings in a certain academic meeting will be included. (Advanced) Practices (10 classes) Practices in pharmacokinetics and application to one s research (Advanced) Exercises (50 classes) Exercises to discuss the findings in research including case studies pharmaceutical dosage design reported in journals in seminar style (Advanced) Preparation for the presentation one s new findings (Advanced) Evaluation Evaluated by performance practices and exercises to prepare one s presentation Pr. Kurosaki and Assoc. Pr. Aiba in their research.

5 Clinical Pharmaceutics and Pharmacokinetics for Dr. Degree 5 credits Class 1-4 Spring and Fall semesters Timetable Monday-Friday (not designated) Pharm. Sci., Tsushima campus Yuji Kurosaki (Pressor, Department Pharmaceutical Formulation Design, Graduate School Medicine, Dentistry and Pharmaceutical Sciences) Tetsuya Aiba (Associate Pressor, Department Clinical Pharmacokinetics, Graduate School Medicine, Dentistry and Pharmaceutical Sciences) 1. To plan one s research 2. To conduct literature searches relating to one s research 3. To discuss one s research results with journal articles 4. To publish one s research as a scientific article 5. To prepare one Dr. Degree Thesis 6. To defense one Dr. Degree Thesis presentation Complete the course with Dr. Degree awarding. Discuss on one s Dr. Degree with specific doctoral adviser and with specific co-supervisor. Evaluation Discussion and supervising by lecturer to accomplish the aims. 1.Planning one s research 2. Conducting literature searches 3. Discussion one s research results 4. Submit one s research to a certain journal 5. Preparation one Dr. Degree Thesis 6. Ability to defense one Dr. Degree Thesis presentation Evaluated by performance practices and exercises to prepare one s presentation Physical pharmaceutics, biopharmaceutics and pharmacokinetics are the majors for Pr. Kurosaki in his research.