David Afshartous, Ph.D. EDUCATION Ph.D. in Statistics (1997) Los Angeles, CA M.S. in Political Science (1990) Cambridge, MA

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1 David Afshartous, Ph.D. tel: Department of Biostatistics, School of Medicine, Vanderbilt University st Avenue South, S2323 MCN, Nashville, TN EDUCATION - Ph.D. in Statistics (1997) Los Angeles, CA University of California, Los Angeles Advisor: Prof. Jan de Leeuw - M.S. in Political Science (1990), Cambridge, MA Massachusetts Institute of Technology - B.S. in Mathematics (1989) Cambridge, MA Massachusetts Institute of Technology EXPERIENCE Research Associate Professor of Biostatistics (9/10 present) Nashville, TN Department of Biostatistics, School of Medicine Vanderbilt University - Statistical design and analysis for research studies: Clinical Pharmacology, Center for Research and Innovation in Systems Safety (CRISS), Hearing and Speech Sciences, U.S. Department of Veterans Affairs. - Supervision of statistical programmers - Research Interests: Prediction models, longitudinal data, clinical trials, Bayesian adaptive designs, machine learning, text classification, Big Data. Research Assistant Professor of Biostatistics (7/07-8/10) Miami, FL Division of Clinical Pharmacology, Department of Medicine, Miller School of Medicine, University of Miami. - Statistical design and analysis for research studies, statistical programming, contributing to entire research protocols. - Development of novel biostatistics methodology, publishing in top clinical and statistical journals. Assistant Professor of Statistics (8/02-7/07) Miami, FL Department of Management Science, School of Business Administration, University of Miami. - Research: prediction in multilevel and mixed effects models, avoiding data snooping in multiple comparisons of random effects, growth curves for repeated measures. - Teaching: data analysis and statistics, regression; MBA and undergraduate level. Wireless Standards Engineer, Applied Statistician (3/00-8/02) London, U.K Lucent Technologies, Bell Labs - Represented and led company s efforts to influence 3GPP wireless standards, Radio Access Network Working Group 2 (RAN2) - 3GPP security, mobility management, overload control, quality of service - Designed functionality for load balancing and overload control for 3G systems 1

2 Network Traffic Systems Engineer, Applied Statistician (11/97-3/00) Naperville, IL Lucent Technologies, Bell Labs - Designed functionality to protect switching systems from heavy traffic - Presented offers to telecom operators at VP level; multi-million dollar sales - Led team that investigated packet data traffic on internal Lucent network Statistical Research Associate ( ) Los Angeles, CA UCLA Statistical Consulting Center - General statistical consulting; led five-person team in analyzing very large national educational data set; mathematical modeling of hierarchical data; reports to National Institute of Statistical Sciences (NISS). High School Mathematics Teacher ( ) New York, NY Julia Richman High School, Manhattan Teaching Assistant for Writing (1990) and Calculus (1989) Cambridge, MA Minority Introduction to Engineering and Science Program, M.I.T. REFEREED PUBLICATIONS 1. Preston, R.A., Afshartous, D., Forte, L., Rodco, R., Alonso, A., M.D., Garg, D., Raij, L. (2012). Sodium challenge does not support an acute gastrointestinal-renal natriuretic signaling axis in humans. Kidney International, in press. 2. Afshartous, D., Preston, R.A. (2011). Key results of interaction models with centering. Journal of Statistics Education. 19(3): Afshartous, D., Preston, R.A. (2010). Confidence Intervals for Dependent Data in Clinical Trials: equating overlap with significance. Computational Statistics and Data Analysis, vol 54, Preston, R.A., Afshartous, D., Garg, D., Medrano S., Alonso A, Rodriguez, R. (2009). Mechanisms of impaired potassium handling with dual renin-angiotensin-aldosterone blockade in chronic kidney disease. Hypertension, vol. 53, Afshartous, D., and Preston, R.A. (2009). Recursive estimation method for predicting residual bladder urine volumes to improve accuracy of timed urine collections, Statistical Methods for Medical Research, vol. 18(2), Afshartous, D., Guan, Y., Mehrotra, A. (2009). U.S. Coast Guard air station location with respect to distress calls: A spatial statistics and optimization based methodology, European Journal of Operational Research, vol. 196(3), Preston, R.A., Afshartous, D., Alonso A.B., Epstein, M. (2008). Randomized Trial of the Effects of Selective versus Nonselective Cyclooxygenase Inhibition on Dynamic Renal Potassium Excretion, Journal of Clinical Pharmacology and Therapeutics, vol. 84(2), Afshartous, D. (2008). Sample size determination for binomial proportion confidence intervals -- an alternative perspective motivated by a legal case, The American Statistician, vol. 62, Afshartous, D. and Wolf, Michael (2007). Avoiding Data Snooping in Mixed and Multilevel Models, Journal of the Royal Statistical Society, Series A, vol. 170, Afshartous, D. and Michailidis, George (2007). Distributed Multilevel Modeling, Journal of Computational and Statistical Graphics, vo1. 16 (4), Guan, Y., Afshartous, D. (2007), Test for independence between marks and points of marked point processes, Ecological and Environmental Statistics, vol. 14 (2),

3 12. Afshartous, D., de Leeuw, Jan (2005). A Predictive Density Approach to Predicting Future Observables in the Multilevel Model, Journal of Statistical Planning and Inference, vol. 128, Afshartous, D., de Leeuw, Jan (2005). Prediction in Multilevel Models, Journal of Educational and Behavioral Statistics, vol. 30 (2), Afshartous, D., de Leeuw, Jan (2005). A Decomposition of Prediction Error for the Multilevel Model, Communications in Statistics Simulation and Computation, vol. 34 (4). 15. Afshartous, D., de Leeuw, Jan (2004). An Application of Multilevel Model Prediction to NELS:88, Behaviormetrika, vol. 31 (1), Teck, H., Afshartous, D., and Young, G. (2004). Resequencing Performance for N- SAW in UMTS HSDPA, Proceeding of the 2004 World Wireless Congress, San Francisco, CA, May Afshartous, D., Guan, Y., Mehrotra, A., and Magnussen, J. (2004). Optimal Deployment of Resources for the U.S. Coast Guard, Proceedings of the 10 th International Conference on Productivity and Quality Research, Miami, Fl, Feb Afshartous, D. (1995), Determination of Sample Size for Multilevel Model Design, Perspectives on Statistics for Educational Research: Proceedings of the National Institute for Statistical Sciences (NISS), Technical Report #35, edited by V.S. Williams, L.V. Jones, and I. Olkin. PATENTS Afshartous, D., Preston, R.A. (2008). U.S. patent application serial number 61/028,640, recursive estimation method for predicting residual bladder urine volumes to improve accuracy of timed urine collections (pending approval) Afshartous, D., Cao, Q., Young, G. (2002). European Patent No : Sequence Number Checking in Communicating Messages in a Universal Mobile Telecommunications (UMTS) Network. PROFESSIONAL Funded Research Performed: 3 rd Generation High Speed Wireless Protocol Performance, MacLamore Research Grant, University of Miami, Role: Principal Investigator (20k). Avoiding Data Snooping in Mixed and Multilevel Models, MacLamore Summer Research Grant, University of Miami, Role: Principal Investigator (20k). Packet Data Analysis Project, Lucent Technologies Dept. # Grant, Role: Principal Investigator (10k). Multilevel Modeling of National Educational Longitudinal Study of 1988 (NELS:88) data, National Institute of Statistics (NISS), Role: Statistician (500k). Pilot Study of the Effects of Dual Blockade of the Renin Angiotensin Aldosterone System on Dynamic Renal Potassium Excretion and Ambulatory Serum Potassium in Patients with Renal Impairment. University of Miami Division of Clinical Pharmacology UMDCP-Study , Preston (PI) 6/07/07 9/1/08. Role: Co-investigator. Preamyloid Oligomers and Susceptibility to Atrial Fibrillation, 1R01HL A1, Murray (PI) 5/1/10-3/31/15. Role: Co-investigator. Enhancing Equitable and Effective PTSD Disability Assessment, SAF (Speroff: PI). 9/1/11-9/30/12. Veterans Administration HSR&D. Role: Statistician. Creating simulation-based performance assessment tools for practicing physicians. R18HS (Weinger :PI), 4/1/11 3/31/14, Agency for Health Care Research and Quality. Role: statistician. 3

4 Fatigue and Listening Effort in School-Aged Children. R324A A1 (Bess:PI) 07/01/12-06/30/15, Institute of Education Sciences. Role: Statistician. Embedding safety-related evidence-based protocols into routine practice (Miller: PI), 10/1/11 6/30/12, Anesthesia Patient Safety Foundation, Role: Statistician. Patient Centered Non-Routine Events, (Weinger: PI). 8/1/12-7/31/14, Patient Centered Outcomes Research Institute (PCORI), Role: Statistician. Factors Contributing to Global Subjective Clinical Assessment (Banerjee: PI). 9/1/12-8/31/14, Foundation for Anesthesia Education and Research (FAER), Role: Statistician. Honors and Awards: Pauley Fellowship, U.C.L.A., Best Ph.D. Qualifying Exam Paper, Department of Political Science, U.C.L.A, American Heart Association Council for High Blood Pressure Research. One of 2 best clinical research papers from Preston, R.A., Afshartous, D., Garg, D., Medrano S., Alonso A, Rodriguez, R. (2009). Mechanisms of impaired potassium handling with dual renin-angiotensin-aldosterone blockade in chronic kidney disease. Hypertension, vol. 53, Conferences and Meetings: Presented a paper at Joint Statistical Meetings, San Diego, CA, Presented a paper at Joint Statistical Meetings, Washington DC, Delegate at 2008 International Biometrics Conference, Dublin, Ireland, Jul Delegate at 2007 FDA-Industry Statistics Workshop, Arlington, VA, Sep Presented a paper at Joint Statistical Meetings, Salt Lake City, UT, Aug Presented a paper at the 6th Amsterdam Conference on Multilevel Analysis, Apr Presented a paper at Institute of Mathematical Statistics annual meeting, Rio de Janeiro, Brazil, Aug Presented a paper at Joint Statistical Meetings, San Francisco, CA, Presented a paper at Joint Statistical Meetings, Baltimore, MD, Presented a paper at Joint Statistical Meetings, Dallas, TX, Presented a paper at Joint Statistical Meetings, Anaheim, CA, Presented a paper at American Educational Research Association (AERA), San Fr, CA, Presented an invited paper at Perspectives on Statistics for Educational Research workshop, the National Institute for Statistical Sciences (NISS), Research Triangle Park, NC, Delegate, Lucent Technologies Bell Labs, 3 rd Generation Partnership Project (3GPP) International Standards, Radio Access Network Work Group 2 (RAN WG2) Pusan, Korea, May Berlin, Germany, Jul Helsinki, Finland, Aug New York, NY, Oct Makuhari, Japan, Nov Sophia-Antipolis, France, Jan Orlando, FL, Feb Kobe, Japan, Apr

5 Gyeoung-Ju, Korea, May Turin, Italy, Jul COMPUTER EXPERIENCE C++, FORTRAN, SAS, SPSS, R, S-PLUS, NONMEM, LaTeX, WinBUGS UNIX, Linux, Mac, Windows ADVANCED TRAINING M210-W Essentials of Population PKPD Modeling & Simulation (1 semester), Metrium Institute Genetic Analysis of Complex Human Diseases (4 days), Miami Institute for Human Genomics Graduate Finance classes: Introduction to Finance ( UCLA), Investments (Vanderbilt), Derivatives (Vanderbilt), Risk Management (Vanderbilt), Bond Markets (Vanderbilt) FOREIGN LANGUAGES Spanish, oral and written; Business presentations to telecom operators in Mexico. Farsi, oral and written Greek, oral and written Turkish, oral and written ACTIVITIES Track Club Miami, founder and coach, 2006 present. Corporate Olympics finalist, 5k 10k run, Track Club Los Angeles, founder and coach, Drumming. 5

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