Sponsored by the University of Pittsburgh School of Medicine Center for Continuing Education in the Health Sciences, UPMC, and

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1 CASCADE 2018 Sponsored by the University of Pittsburgh School of Medicine Center for Continuing Education in the Health Sciences, UPMC, and ITxM DIAGNOSTICS Pittsburgh, Pennsylvania MAY 4, 2018 Sheraton Station Square Pittsburgh, Pennsylvania

2 Note From Our Course Director Dear Colleagues, It is with great pleasure that we are holding our next CASCADE 2018: Advances In Hemostasis & Thrombosis Conference on Friday, May 4, 2018, at the Sheraton Station Square - the meeting that has become a regional favorite. Our annual conference continues to be a comprehensive one-day event, concentrating on the latest science, trends, and recommendations for the prevention, diagnosis, and treatment of both thrombosis and hemostasis issues. By annually gathering physicians and health care professionals across multiple medical disciplines, our intent is to keep the attendees at the forefront of the latest information on both of these issues, so they may better serve and care for the patients they see in their practices. Our speakers and topics this year will again provide an abundance of the latest information, allowing for provocative questions, lively discussion, cutting edge research and scientific information. If you require any further detailed information or have any questions, please contact: Deb Small at or by at dsmall@itxm.org. As always, we look forward to seeing you at another exciting event on Friday May 4, 2018 at the Sheraton Station Square. Warm regards, Franklin A. Bontempo, MD FRANKLIN A. BONTEMPO, MD Medical Director, ITxM Diagnostics Associate Professor of Medicine University of Pittsburgh School of Medicine Division of Hematology/Oncology Pittsburgh, Pennsylvania

3 FACULTY Mark Crowther, MD, MSc, FRCPC Professor, Department of Medicine, Hematology and Thromboembolism and Pathology and Molecular Medicine McMaster University, Hamilton, Ontario David A. Garcia, MD Professor of Medicine, University of Washington School of Medicine, Seattle, WA Stephan Moll, MD Professor of Medicine, University of North Carolina School of Medicine Department of Medicine, Division of Hematology-Oncology Chapel Hill, NC Sam Schulman, MD Prof. at the Dept. of Medicine, McMaster University, Hamilton ON, Canada Director of Clinical Thromboembolism Program in Hamilton ON Jansen Seheult, MD ITxM Fellow Pittsburgh, Pennsylvania Frederico Xavier, MD, MS Associate Medical Director, Hemophilia Center of Western PA Assistant Professor of Pediatrics University of Pittsburgh Pediatric Hematology/Oncology Children s Hospital of Pittsburgh of UPMC Ryan Zarychanski, MD, MSc, FRCPC Associate Professor of the Department of Medicine Critical Care and Hematology/ Medical Oncology University of Manitoba, Winnipeg, Manitoba Faculty Disclosure: All individuals in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any proprietary entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by patients.

4 SCHEDULE 7:00-7:50 am Registration/Coffee 7:50-8:00 am Welcome/Introductions Franklin A. Bontempo, MD MODERATOR: FRANKLIN A. BONTEMPO, MD 8:00-8:50 am David A. Garcia, MD Direct Oral Anticoagulants For Cancer Associated Thrombosis 8:50 9:40 am Frederico Xavier, MD, MS Acquired von Willebrand's Syndrome 9:40-9:55 am 9:55-10:45 am BREAK Mark Crowther, MD Reversing Anticoagulants: New & Old 10:45-11:35 am Ryan Zarychanski, MD Assessing thrombocytopenia in the intensive care unit: The past, present and future 11:35-12:45 pm LUNCHEON MODERATOR: Irina Chibisov, MD 12:45 1:35 pm Stephan Moll, MD Hormones and Thrombosis 1:35 2:25 pm Sam Schulman, MD Management of Splanchnic Vein Thrombosis 2:25-3:15 pm Jansen Seheult, MD Laboratory diagnosis of the lupus anticoagulant: Controversies, Pitfalls and Future Directions 3:15 pm - 3:30 pm QUESTIONS, DISCUSSION, ADJOURNMENT

5 WHO SHOULD ATTEND THIS MEETING This conference is intended for family practice, internal medicine, cardiologists, surgeons, hematologists, oncologists, neurologists, interventional radiologists, residents, fellows, PA s, CRNPs, RNs and any interested health care professionals. CONTINUING EDUCATION CREDITS This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the University of Pittsburgh School of Medicine and the Institute For Transfusion Medicine. The University of Pittsburgh School of Medicine is accredited by the ACCME to provide continuing medical education for physicians. The University of Pittsburgh School of Medicine designates this live activity for a maximum of 6.25 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded 0.6 continuing education units (CEU s) which are equal to 6.2 contact hours. VISIT THE CENTER FOR CONTINUING EDUCATION IN THE HEALTH SCIENCES WEB SITE Our Internet address: The UPMC/Center for Continuing Education in the Health Sciences invites you to visit our web location. Receive information on CME programs, earn CME credits on the Internet, and access information about our formal courses and much more. Discover who we are and how you can contact us. Please visit our web location often to get updated information on upcoming programs. SPECIAL NEEDS Participation by all individuals is encouraged. Advance notification of any special needs will help us provide better service. Please notify us of your needs at least two weeks in advance of the program by calling The University of Pittsburgh is an affirmative action, equal opportunity institution.

6 REGISTRATION INFORMATION All registration forms MUST be postmarked by April 23, 2018 to preregister for this conference. We cannot guarantee space in the program or any program inclusions for those registrations received after this date. Payment must accompany your registration. CANCELLATION/REFUND INFORMATION All cancellations must be in writing and sent to us via U.S. mail, or fax (see contact information below). Tuition for cancellations postmarked or date stamped before April 15, 2018 will be refunded in full. After April 15, 2018, a $35.00 administrative fee will be assessed and the remaining amount refunded - and no refunds will be made after April 27, The University of Pittsburgh School of Medicine reserves the right to cancel this program if we do not receive a sufficient number of advance registrations. In the case of cancellation, the department will refund the registrations received. For more information contact: Deborah S. Small, Conference Planner Telephone: (412) Fax: (412) dsmall@itxm.org OBJECTIVES At the conclusion of this program, the participants should have a better understanding of: increased knowledge of the latest drug therapies and treatment plans for hypercoagulopathies in various populations. increased knowlege concerning the latest test methods, and the significance of their results in diagnoses such as LACs, ahus, thrombocytopenia, stroke in pregnancy, etc. increased knowlege about the latest oral anticoagulants in the market place and the uses

7 REGISTRATION CASCADE 2018: Advances In Hemostasis &Thrombosis Conference May 4, 2018 Course #: 7137 PLEASE TYPE OR PRINT ALL INFORMATION: PHOTOCOPIES FOR ADDITIONAL REGISTRANTS WELCOME NAME ADDRESS CITY STATE ZIP WORK PHONE ( ) FAX ( ) CELL PHONE ( ) LAST 5 DIGITS OF SSN: (The last 5 digits of your SSN are needed to obtain your CME credits) Please print address clearly Address Specialty Degree Institutional affiliation $ Physicians $ Fellows, Residents, CRNP s, RNs $ Registration At The Door Includes: Continuing education credits Registration and course materials Continental Breakfast and Lunch We will not accept registration without payment. Checks Payable To: ITxM Diagnostics or Charges Taken: MC, Visa, Discover CARD #: EXP. SC Send Payments with this Form To: Deborah S. Small ITxM Diagnostics 3636 Blvd. of the Allies Pittsburgh, PA

8 3636 Blvd. of the Allies Pittsburgh, PA Non-Profit Org. U.S. Postage PAID Pittsburgh, PA Permit #2516

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