Julia C. van Kessel, Ph.D.

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1 Julia C. van Kessel, Ph.D. Molecular and Cellular Biochemistry Department, Indiana University 212 S. Hawthorne Drive, Simon Hall MSB, room 400B, Bloomington, IN Phone: Education 2008 Doctor of Philosophy in Molecular, Cellular, and Developmental Biology ; Advisor: Graham Hatfull, Ph.D. Thesis title: Recombineering in mycobacteria with mycobacteriophage proteins. Minor in Teaching 2003 Bachelor of Science in Biology, graduated Magna cum laude Utica College of Syracuse University Graduated with Major Honors in Biology and General College Honors Research Research and Professional Experience 2014 Present Assistant Research Scientist Department of Molecular and Cellular Biochemistry Affiliated with the Microbiology Program in the Department of Biology Indiana University Postdoctoral Research Fellow Advisor: Bonnie Bassler, Ph.D Graduate Student Researcher Advisor: Graham Hatfull, Ph.D Undergraduate Student Researcher Utica College of Syracuse University Advisor: Lawrence Aaronson, Ph.D. Scientific Writing Editor American Journal Experts Content Reviewer American Journal Experts Awards Honors and Awards National Institutes of Health Ruth L. Kirschstein National Research Service Award, National Institute of General Medical Sciences 1F32GM , ; **received perfect impact score 2009 Nat L. Sternberg Thesis Prize; awarded for an outstanding Ph.D. thesis in the field of prokaryotic molecular biology, presented at the Molecular Genetics of Bacteria and Phages meeting 3

2 2004 Ivy R. McManus Scholar; awarded for outstanding academic performance during the first year of graduate study; Fellowships Andrew Mellon Pre-doctoral Fellowship; awarded for exceptional promise and ability ; 2003 American Society for Microbiology Undergraduate Research Fellowship; Utica College of Syracuse University Publications 1. Feng L, Rutherford ST, Papenfort K, Bagert JD, van Kessel JC, Tirell DA, Wingreen NS, and Bassler BL. The quorum-sensing non-coding RNAs use four different mechanisms to regulate target mrnas. (2014) Cell. In press. 2. van Kessel JC*, Rutherford ST, Cong JP, Quinodoz S, Healy J, and Bassler BL*. Quorum sensing regulates the osmotic stress response in Vibrio harveyi. (2014) Journal of Bacteriology. 197 (1): *Co-corresponding authors 3. van Kessel JC, Ulrich LE, Zhulin IB, and Bassler BL. Analysis of activator and repressor functions reveals the requirements for transcriptional control by LuxR, the master regulator of quorum sensing in Vibrio harveyi. (2013) mbio 4 (4): e **Highlighted as an Editor s Pick in mbio. 4. van Kessel JC, Rutherford ST, Shao Y, Utria AF, and Bassler BL. Individual and Combined Roles of the Master Regulators AphA and LuxR in Control of the Vibrio harveyi Quorum-Sensing Regulon. (2013) Journal of Bacteriology 195 (3): Rutherford ST, van Kessel JC, Shao Y, and Bassler BL. AphA and LuxR/HapR reciprocally control quorum sensing in vibrios. (2011) Genes and Development 25 (4): van Kessel JC, Marinelli LM, and Hatfull GF. Recombineering mycobacteria and their phages. (2008) Nature Reviews Microbiology 6 (11): Marinelli LM, Oldfield L, Payne K, Swiganova S, van Kessel JC, and Hatfull GF. BRED: a simple and powerful tool for constructing mutant and recombinant bacteriophage genomes. (2008) PLOS One 3 (12): e van Kessel JC and Hatfull GF. Efficient point mutagenesis in mycobacteria using single-stranded DNA recombineering: characterization of anti-mycobacterial drug targets. (2008) Molecular Microbiology 67 (5): van Kessel JC and Hatfull GF. Mycobacterial Recombineering, in Davis GD and Kayser KJ, Chromosomal Mutagenesis. (2008) Methods in Molecular Biology 435: van Kessel JC and Hatfull GF. Recombineering in Mycobacterium tuberculosis. (2007) Nature Methods 4 (2): **Selected for the cover image/article. **Highlighted as a Nature Methods Technology Feature. Grants Awarded Grants Indiana Drug Discovery Alliance, Indiana CTSI; $15,000; Chemical screen for inhibitors of quorum sensing in vibrios. Invited Seminars 4

3 2013 Binghamton University Department of Biological Sciences 2013 DuPont Research and Development Biotechnology Division 2012 Bard College Biology Research Seminar Series 2012 Princeton High-Throughput Sequencing Users group meeting, University/Department service Academic Service 2014 Present Indiana University Bloomington Institutional Biosafety Committee Thesis committees: Ad Hoc Reviewer: Nandhini Ashok, Microbiology Meng Pu, Microbiology FEMS, Microbial Drug Resistance General 2014 Present Nominating Committee for ASM Division W Chair-Elect Co-President of the Biological Sciences graduate student organization, University of Pittsburgh Graduate student committee for seminar speaker invitation, Co-Chair of the Biological Sciences graduate student recruiting committee, University of Pittsburgh Oral Presentations Scientific Conferences and Presentations 2009 Molecular Genetics of Bacteria and Phages Conference 2007 Molecular Genetics of Bacteria and Phages Conference 2003 American Society for Microbiology 103 rd General Meeting 2003 Utica College Student Research Conference Poster Presentations 2012 American Society for Microbiology 112 th General Meeting 2010 American Society for Microbiology 110 th General Meeting 2009 American Society for Microbiology 109 th General Meeting 2008 American Society for Microbiology 108 th General Meeting 2007 American Society for Microbiology 107 th General Meeting 2006 Science American Society for Microbiology 106 th General Meeting 2005 Science Molecular Genetics of Bacteria and Phages Conference 2005 International Union of Microbiological Societies 2005 American Society for Microbiology 105 th General Meeting 2004 Science American Society for Microbiology 104 th General Meeting 2003 Science American Society for Microbiology 103 rd General Meeting 2003 Council on Undergraduate Research, Posters on the Hill 2002 American Society for Microbiology 102 nd General Meeting 5

4 Classes taught Teaching Experience 2009 Research discussion group, Summer Undergraduate Research Program, Princeton University 2004 Teaching Assistant, Introduction to Microbiology Lab, 2002 Teaching Assistant, Molecular Biology, Utica College of Syracuse University 2002 Teaching Assistant, Physics I, Utica College of Syracuse University 2001 Teaching Assistant, Cell Biology, Utica College of Syracuse University Guest lectures 2012 Invited guest lecturer, General Biology, Microbiology, University of the Sciences Outreach Programs 2014 Indiana Junior Academy of Science Research Competition judge 2014 Indiana University Introductory Biotechnology Course for High School Science Teachers, lecturer 2014 Wonderlab Program Partner for Real Life Science: Anyone Can Be a Scientist HHMI Ask a Scientist program volunteer Science and Engineering Expo volunteer,, annually 2012 Day of Biology volunteer, Stuart School 2009 HHMI Holiday Lectures with Bonnie Bassler 2006 SEPA-funded teaching and research program, The Gene Team, Indiana University Students Trained Graduate students 2014 present Ryan Chaparian Biochemistry 2014 present Alyssa Ball Microbiology Rotation students Fall 2014 Alyssa Ball Microbiology Fall 2014 Reid Oshiro Microbiology Fall 2014 Ryan Chaparian Biochemistry Fall 2014 Allissa Haney Biochemistry Undergraduate students 2014 Present Stephen Olney 2014 Present Cole McCutcheon Center of Excellence for Women in Technology Emerging Scholars Research Experience for Undergraduate Women (CEWiT-REUW) 2014 Present Christine Hustmyer Khorana Scholars Program Summer 2014 Sanika Hakim Three rotation students (Anne McCabe, Rory Zhou Li, Nicholas Ouzounov) 6

5 Three undergraduate students (Amanda Izzo, Sofia Quinodoz, Yihe Dong) Four undergraduate students (Angela Sprigle, Daniel Nava, Peter Morris, Rebecca Weber) Memberships American Association for the Advancement of Science, sponsored membership 2003 Present Sigma Xi Scientific Research Society, Inducted, Hamilton College Chapter 2002 Present American Society for Microbiology Asa Gray Biological Society, Utica College Bonnie L. Bassler, Ph.D. Chair and Squibb Professor in Molecular Biology Howard Hughes Investigator Graham F. Hatfull, Ph.D. Eberly Family Professor HHMI Professor Department of Biological Sciences Frederick M. Hughson, Ph.D. Professor Ned S. Wingreen, Ph.D. Howard A. Prior Professor of the Life Sciences References 7

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