PUERTO RICO. Bioscience Performance Metrics. Puerto Rico Page 1

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1 PUERTO RICO Puerto Rico has a highly specialized bioscience industry. The territory has an extremely high employment specialization (location quotient of 11.0) and more than percent of national employment in the drugs and pharmaceuticals subsector, and an additional very strong employment specialization in medical devices and equipment (location quotient of.) and in research, testing and medical laboratories (1.). Total academic bioscience research and development expenditures were $. million in, mainly in the medical sciences. Puerto Rico had bioscience venture capital investments in, 200, and, totaling $0.8 million, all in medical/health services. Puerto Rican higher education institutions graduated 1,2 students with degrees in bioscience related fields in, contributing to the industry s talent base. Bioscience Performance Metrics Summary of State Performance in Selected Bioscience related Metrics Metrics Puerto Rico United States Rank* Bioscience Industry, Total Bioscience Industry Employment, 4,104 1,420,24 I Bioscience Industry Location Quotient, 4.8 n/a I Biosciences Industry Establishments, 88 4,9 II Academic R&D Expenditures, FY Bioscience R&D ($ thousands) $,4 $1,818,810 4 Bioscience Share of Total R&D.% 1.% 2 Bioscience R&D Per Capita $14. $ Change in Bioscience R&D, FY 08 0.% 22.% 4 NIH Funding, FY 2009 Total, Including ARRA Funds ($ thousands) $,429 $2,8,90 42 Per Capita Funding $1.4 $ Change in Baseline Funding, FY 09** 4.% 4.% 1 Change in Total Funding, FY % 14.% 8 Clinical Trials, Initiated ,299 4 Higher Education Degrees in Bioscience Fields, AY 1,2 11,811 Employment in Bioscience related Occupations, 4,900 1,10 Bioscience Venture Capital Investments, 09 ($ millions) $0.8 $0, Bioscience and Related Patents, 09,9 1 *State ranking figures for bioscience industry employment metrics are calculated as quintiles (I=Top Quintile; V=Bottom Quintile). All other metrics are ranked 1 2. **Baseline Funding does not include American Recovery and Reinvestment Act (ARRA) funds for For source notes, see end of State Profile. Puerto Rico Page 1

2 Bioscience Industry Base, INDUSTRY SUBSECTOR Puerto Rico United States Change Change AGRICULTURAL FEEDSTOCK & CHEMICALS Establishments 2, % Employment 114,9 1.9% Location Quotient n/a Direct Effect Employment Multiplier 11. Total Employment Impact 1,284,0 Average Annual Wage $2,29 DRUGS & PHARMACEUTICALS Establishments 4 2.% 2,1.4% Employment 22,.0% 11,882 2.% Location Quotient 11.0 n/a Direct Effect Employment Multiplier N/A 9.92 Total Employment Impact N/A 2,8,28 Average Annual Wage $1,4 $9,8 MEDICAL DEVICES & EQUIPMENT Establishments % 1,22 0.4% Employment 1,19 10.% 4,09 2.0% Location Quotient. n/a Direct Effect Employment Multiplier N/A 4.8 Total Employment Impact N/A 2,029,81 Average Annual Wage $,44 $,0 RESEARCH, TESTING, & MEDICAL LABORATORIES Establishments 01 2.% 2,14.% Employment, 0.4% 8, % Location Quotient 1. n/a Direct Effect Employment Multiplier N/A.0 Total Employment Impact N/A 1,8,12 Average Annual Wage $2,2 $80,8 TOTAL BIOSCIENCES INDUSTRY Establishments % 4,9 28.% Employment 4, % 1,420,24 1.8% Location Quotient 4.8 n/a Direct Effect Employment Multiplier N/A.82 Total Employment Impact N/A 8,040, Average Annual Wage $4,88 $,9 TOTAL PRIVATE SECTOR Establishments,0 12.0% 8,80,9 1.8% Employment 1,100 1.% 11,91,.% Average Annual Wage $24,0 $4,229 Note: U.S. employment metrics include Puerto Rico. Estimates of total employment impacts do not include Puerto Rico. Puerto Rico Page 2

3 Bioscience Performance Metrics Bioscience Academic R&D Expenditures in Puerto Rico, FY NIH Awards in Puerto Rico, 2009 Medical $1,88 $0 Biological $,120 $4 Agricultural Other Life $112 $1 200 $ $0 $9 Bio/Biomedical Engineering $ ARRA $ $0 $1,000 $0,000 $4,000 $0,000 Academic R&D Expenditures ($ Thousands) $0 $2 $0 $ NIH Funding ($ Millions) Recent Clinical Trial Activities Clinical Trials by Phase in Puerto Rico, 2009 Clinical Trials by Major Disease Category in Puerto Rico, Phase I 2 2 Phase II Phase III Phase IV Clinical Trials 0 Cancer Circulatory Heart Disease Infectious Disease Disease Category Neurologic Nutritional & Metabolic Other Puerto Rico Page

4 Bioscience Talent Base Bioscience related Occupational Employment in Puerto Rico, Bioscience related Degrees in Puerto Rico, AY Agricultural, Food & Nutrition Scientists & Technicians 120 Agricultural, Food, & Nutrition Science Biological Scientists & Technicians Medical & Clinical Laboratory Technicians Biomedical & Biochemical Scientists & Engineers 1,190,90 Biological Bio Medical & Engineering Medical & Veterinary Other Life Science Fields Associate's (AA/AS) Bachelor's (BS/BA) Master's (MS/MA) Doctorate (PhD) 0 1,000 2,000,000 4,000 Occupational Employment ,000 Degrees Bioscience Venture Capital Bioscience related Venture Capital Investments in Puerto Rico, 2009 Bioscience related Venture Capital Investments in Puerto Rico by Segment, 2009 Biofuels Biosensors Biotech Animal Biotech Equipment $10.8 Biotech Human Biotech Industrial 200 $8.0 Biotech Other $12.0 Biotech Research Med/Health Info Tech $0 $ $10 $1 Venture Capital Investments ($ Millions) Med/Health Products Med/Health Services Medical Diagnostics Medical Therapeutics $0.8 $0 $10 $20 $0 $40 Venture Capital Investments ($ Millions) Puerto Rico Page 4

5 Bioscience Patents Bioscience related Patents in Puerto Rico, 2009 Bioscience related Patents by Classification Group in Puerto Rico, Agricultural Bioscience Biochemistry Biotechnology Drugs & Pharmaceuticals Surgical & Medical Instruments Other Medical Equipment Other Bioscience Related Patents Patents State Bioscience Contact INDUNIV Research Consortium FD Roosevelt Avenue, Suite 02 San Juan, PR P: (8) F: (8) Source Notes: Employment, Establishment, and Wage Data: U.S. Bureau of Labor Statistics, Quarterly Census of Employment and Wages (QCEW) industry data provided by the Minnesota IMPLAN Group, 2001 and. Employment Multipliers: U.S. Bureau of Economic Analysis RIMS II Employment Multipliers, (most currently available). Academic R&D Expenditures: National Science Foundation (NSF) Survey of Research and Development Expenditures at Universities and Colleges, and. NIH Funding: National Institutes of Health, Office of Extramural Research, Award Trends, Dollars Awarded by State, and Clinical Trials: National Institutes of Health, Clinicaltrials.gov, trials that were initiated in Higher Education Degrees: National Center for Educational Statistics, Integrated Postsecondary Education Data System (IPEDS),. Occupational Employment: U.S. Bureau of Labor Statistics, Occupational Employment Statistics (OES) survey data,. Venture Capital: Thomson Reuters VentureXpert Database, 2009, as of January 1, Patents: U.S. Patent & Trademark Office data as available from the Thomson Reuters Delphion Patent Analysis Database, 2009, as of January 1, For a more detailed discussion of the data and methodology used, please see the Appendix to the full national report Puerto Rico Page