NITRIC OXIDE AND THE CARDIOVASCULAR SYSTEM
|
|
- Debra Walsh
- 6 years ago
- Views:
Transcription
1 NITRIC OXIDE AND THE CARDIOVASCULAR SYSTEM
2 CONTEMPORARY CARDIOLOGY Christopher P. Cannon, Series Editor Management of Acute Coronary Syndromes, edited by Christopher P. Cannon, 1999 Minimally Invasive Cardiac Surgery, edited by Mehmet C. Oz and Daniel J. Goldstein, 1999 Annotated Atlas of Electrocardiography: A Guide to Confident Interpretation edited by Thomas M. Blake, 1999 Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease, edited by A. Michael Lincoff and Eric J. Topol, 1999 Nitric Oxide and the Cardiovascular System, edited by Joseph Loscalzo and Joseph A. Vita, 2000
3 NITRIC OXIDE AND THE CARDIOVASCULAR SYSTEM Edited by JOSEPH LOSCALZO, MD, PHD JOSEPH A. VITA, MD Boston University Medical Center, Boston, MA SPRINGER SCIENCE+BUSINESS MEDIA, LLC
4 2000 Springer Science+Business Media New York Originally published by Humana Press Inc in 2000 Softcover reprint of the hardcover 1st edition 2000 All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise without written permission from the Publisher. All articles, comments, opinions, conclusions, or recommendations are those of the author(s), and do not necessarily reflect the views of the publisher. Due diligence has been taken by the publishers, editors, and authors of this book to assure the accuracy of the information published and to describe generally accepted practices. The contributors herein have carefully checked to ensure that the drug selections and dosages set forth in this text are accurate and in accord with the standards accepted at the time of publication. Notwithstanding, as new research, changes in government regulations, and knowledge from clinical experience relating to drug therapy and drug reactions constantly occurs, the reader is advised to check the product information provided by the manufacturer of each drug for any change in dosages or for additional warnings and contraindications. This is of utmost importance when the recommended drug herein is a new or infrequently used drug. It is the responsibility of the treating physician to determine dosages and treatment strategies for individual patients. Further it is the responsibility of the health care provider to ascertain the Food and Drug Administration status of each drug or device used in their clinical practice. The publisher, editors, and authors are not responsible for errors or omissions or for any consequences from the application of the information presented in this book and make no warranty, express or implied, with respect to the contents in this publication. ISBN ISBN (ebook) DOI / Cover design by Patricia F. Cleary. This publication is printed on acid-free paper. ANSI Z (American National Standards Institute) Permanence of Paper for Printed Library Materials. Photocopy Authorization Policy: Authorization to photocopy items for internal or personal use, Springer Science+Business Media, LLC provided that the base fee of US $10.00 per copy, plus US $00.25 per page, is paid directly to the Copyright Clearance Center at 222 Rosewood Drive, Danvers, MA For those organizations that have been granted a photocopy license from the CCC Library of Congress Cataloging-in-Publication Data
5 PREFACE The field of nitric oxide biology has expanded considerably over the past decade with a growing appreciation of its many roles in a variety of cell and organ systems. Nitric oxide was first discovered in the cardiovascular system, and the importance of this discovery led to the award of the 1998 Nobel Prize in Physiology or Medicine to Robert Furchgott, Louis Ignarro, and Fred Murad, well-known cardiovascular investigators. With this history, it should come as no surprise that our understanding of the role of nitric oxide in biology and pathobiology is, perhaps, best developed as it relates to cardiovascular biology and disease. For this reason, we felt it would be both timely and relevant to review in detail the role of nitric oxide in cardiovascular biomedicine. To this end, we assembled a group of contributing authors with expertise in areas that include the chemistry of nitric oixide, the biochemistry of its synthesis, the molecular biology of nitric oxide synthases, the pharmacology of nitrovasodilators, and the role of nitric oxide in vascular diseases. With the recent expansion of the field in directions that range from the development of novel nitric oxide donors for the treatment of myocardial ischemia and thrombosis to the development of gene therapy approaches for the restoration of endothelial function in atherosclerosis, the application of nitric oxide biology to investigative and clinical arenas in cardiovascular medicine is, indeed, rapidly evolving. This comprehensive overview should prove useful for basic and clinical investigators alike, as well as practicing clinicians in the fields of cardiology, hematology, and vascular medicine. With a balanced presentation of basic and clinically relevant subject matter, this text will provide a compendium of information that may guide the reader through the foundations of the most recent developments in this rich and exciting field. ACKNOWLEDGMENT We thank Stephanie Tribuna for her assistance throughout the many phases of the development of this text, and Jalna Ross for her assistance in reference verification. Joseph Loscalzo, MD, PHD Joseph A. Vita, MD v
6 To Anita, Julia, Alex, Gina, Olivia, and Sam
7 CONTENTS Preface... v Contributors... ix PART I BIOLOGY OF NITRIC OXIDE The Biological Chemistry of Nitric Oxide... 3 Joseph Loscalzo 2 Cell and Molecular Biology of Nitric Oxide Synthases Olivier Feron and Thomas Michel 3 Cellular Signal Transduction and Nitric Oxide Stanley Heydrick 4 Regulation of Gene Expression by Nitric Oxide Ami A. Deora and Harry M. Lander 5 Cytotoxicity, Apoptosis, and Nitric Oxide Stefanie Dimmeler and Andreas M. Zeiher 6 Nitric Oxide and Ion Channels Victoria M. Bolotina 7 Role of Nitric Oxide in Vasomotor Regulation Richard A. Cohen 8 Nitric Oxide and Platelet-Mediated Hemostasis Elisabeth M. Battinelli and Joseph Loscalzo 9 Nitric Oxide Modulates Leukocyte Endothelial Cell Adhesion. 139 Wolfgang Cerwinka and D. Neil Granger 10 Nitric Oxide and Cardiomyocyte Function Jean-Luc Balligand and Paul J. Cannon 11 The Fibroblast and Nitric Oxide Peter Brecher 12 Nitric Oxide in Cardiac Electrophysiology Lü Fei and Douglas P. Zipes PART II CARDIOVASCULAR PATHOPHYSIOLOGY OF NITRIC OXIDE Nitric Oxide and Endothelial Dysfunction Gerard A. Dillon and Joseph A. Vita 14 Nitric Oxide and Hypertension M. Audrey Rudd, María R. Trolliet, and Joseph Loscalzo 15 Nitric Oxide and Pulmonary Hypertension John J. Leopore and Kenneth D. Bloch 16 Nitric Oxide in Atherosclerosis Robert T. Eberhardt and Joseph Loscalzo vii
8 viii Contents 17 Thrombotic Disorders and Nitric Oxide Insufficiency Jane E. Freedman and Joseph Loscalzo 18 Myocardial Nitric Oxide in Heart Failure Douglas B. Sawyer and Wilson S. Colucci 19 Shock States and Nitric Oxide Hartmut Ruetten and Christoph Thiemermann 20 Stroke and Nitric Oxide Nancy E. Stagliano and Paul L. Huang 21 The Role of Nitric Oxide in Ischemia-Reperfusion Allan M. Lefer and Reid Hayward PART III NITRIC OXIDE IN CARDIOVASCULAR THERAPEUTICS Nitrovasodilators John D. Horowitz 23 S-Nitrosothiols Jane A. Leopold and Joseph Loscalzo 24 Diazeniumdiolates (Formerly NONOates) in Cardiovascular Research and Potential Clinical Applications Joseph E. Saavedra, Anthony L. Fitzhugh, and Larry K. Keefer 25 Inhaled Nitric Oxide Therapy for Acute Respiratory Failure William Hurford and Warren M. Zapol 26 Antioxidants and Endothelium-Derived Nitric Oxide Action Annong Huang and John F. Keane`y, Jr. 27 Coating Arterial and Blood-Contacting Surfaces with NO -Donating Compounds John D. Folts and Joseph Loscalzo 28 Gene Therapy and Nitric Oxide Heiko E. von der Leyen 29 Nitric Oxide and Tissue Preservation in Transplantation David J. Pinsky and David M. Stern 30 L-Arginine: Its Role in Cardiovascular Therapy Andrew J. Maxwell and John P. Cooke Index
9 CONTRIBUTORS JEAN-LUC BALLIGAND, MD, PHD Department of Medicine, Pharmacology Unit, University of Louvain Medical School, Brussels, Belgium ELIZABETH M. BATTINELLI, MSC Whitaker Cardiovascular Institute and Evans Department KENNETH D. BLOCH, MD Cardiology Division and the Cardiovascular Research Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA VICTORIA BOLOTINA, PHD Vascular Biology Unit, Evans Department of Medicine, Boston University School of Medicine, Boston, MA PETER BRECHER, PHD Boston University School, of Medicine, Whitaker Cardiovascular Institute, Boston, MA PAUL J. CANNON, MD Department of Medicine, Division of Cardiology, Columbia University College of Physicians and Surgeons, New York, NY WOLFGANG CERWINKA, MD Department of Molecular and Cellular Physiology, Louisiana State University Medical Center, Shreveport, LA RICHARD A. COHEN, MD Vascular Biology Unit, Evans Department of Medicine, Boston University School of Medicine, Boston, MA WILSON S. COLUCCI, MD, FACC Myocardial Biology Unit, Boston University School of Medicine, and Cardiovascular Division, Department of Medicine, Boston University Medical Center, Boston, MA JOHN P. COOKE, MD, PHD Section of Vascular Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA AMI A. DEORA, PHD Department of Biochemistry, Cornell University Medical College, New York, NY GERARD DILLON, MD Evans Department of Medicine and Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA STEFANIE DIMMELER, PHD Molecular Cardiology, Department of Internal Medicine IV, University of Frankfurt, Germany ROBERT T. EBERHARDT, MD Whitaker Cardiovascular Institute and Evans Department LÜ FEI, MD, PHD Krannert Institute of Cardiology, Department of Medicine, Indiana University School of Medicine, and the Roudebush Veterans Administration Medical Center, Indianapolis, IN OLIVIER FERON, PHD Pharmacology and Therapeutic Unit, Department of Medicine, University of Louvain Medical School, Brussels, Belgium ANTHONY L. FITZHUGH, MD Intramural Research Support Program, SAIC Frederick, National Cancer Institute, Frederick Cancer Research and Development Center, Frederick, MD JOHN D. FOLTS, PHD, FACC Coronary Thrombosis Research Laboratory, Department of Cardiology, University of Wisconsin Medical School, Madison, WI JANE E. FREEDMAN, MD Department of Clinical Pharmacology, Georgetown University, Washington, DC ix
10 x Contributors D. NEIL GRANGER, PHD Department of Molecular and Cellular Physiology, Louisiana State University Medical Center, Shreveport, LA REID HAYWARD, PHD Department of Physiology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA STANLEY HEYDRICK, PHD Boston University School of Medicine, Boston, MA JOHN D. HOROWITZ, MBBS, PHD Cardiology Unit, The Queen Elizabeth Hospital, Woodville, Australia ANNONG HUANG, PHD Evans Memorial Department of Medicine and Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA PAUL L. HUANG, MD, PHD Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA WILLIAM E. HURFORD, MD Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, MA JOHN F. KEANEY, JR., MD Evans Memorial Department of Medicine and Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA LARRY K. KEEFER, PHD Chemistry Section, Laboratory of Comparative Carcinogenesis, National Cancer Institute, Frederick Cancer Research and Development Center, Frederick, MD HARRY M. LANDER, PHD Department of Biochemistry, Cornell University Medical College, New York, NY ALLAN M. LEFER, PHD Department of Physiology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA JANE A. LEOPOLD, MD Whitaker Cardiovascular Institute and Evans Department JOHN J. LEPORE, MD Cardiology Division and the Cardiovascular Research Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA JOSEPH LOSCALZO, MD, PHD Whitaker Cardiovascular Institute and Evans Department ANDREW J. MAXWELL, MD Cooke Pharma, Belmont, CA THOMAS MICHEL, MD, PHD Cardiology Division, West Roxbury VA Medical Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA DAVID J. PINSKY, MD Divisions of Cardiology and Circulatory Physiology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY M. AUDREY RUDD, PHD Whitaker Cardiovascular Institute and Evans Department HARTMUT RUETTEN, MD The William Harvey Research Institute, St. Bartholomew's and the Royal London School of Medicine and Dentistry, London, UK JOESPH E. SAAVEDRA, PHD Intramural Research Support Program, SAIC Frederick, National Cancer Institute, Frederick Cancer Research and Development Center, Frederick, MD DOUGLAS B. SAWYER, MD Myocardial Biology Unit, Boston University School of Medicine, and Cardiovascular Division, Department of Medicine, Boston University Medical Center, Boston, MA
11 Contributors xi NANCY E. STAGLIANO, PHD Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA DAVID M. STERN, MD Divisions of Cardiology and Circulatory Physiology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY CHRISTOPH THIEMERMANN, MD The William Harvey Research Institute, St. Bartholomew's and the Royal London School of Medicine and Dentistry, London, UK MARÍA R. TROLLIET, PHD Whitaker Cardiovascular Institute and Evans Department JOSEPH A. VITA, MD Evans Department of Medicine and Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA HEIKO E. VON DER LEYEN, MD, PHD Cardiogene AG, Erkrath, Germany, and Department Innere Medizin, Medizinische Hochschule, Hannover, Germany WARREN M. ZAPOL, MD Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, MA ANDREAS M. ZEIHER, MD Molecular Cardiology, Department of Internal Medicine IV, University of Frankfurt, Germany DOUGLAS P. ZIPES, MD Krannert Institute of Cardiology, Department of Medicine, Indiana University School of Medicine, and the Roudebush Veterans Administration Medical Center, Indianapolis, IN
THE PROMOTION OF SOCIAL AWARENESS
THE PROMOTION OF SOCIAL AWARENESS Powerful Lessons from the Partnership of Developmental Theory and Classroom Practice Robert L. Selman Russell Sage Foundation New York The Russell Sage Foundation The
More informationParamedic Science Program
Paramedic Science Program Paramedic Science Program Faculty Chair Michael Mikitish Chair, Emergency Services Department Emergency Medical Services (EMS) An Associate of Science degree in Paramedic Science
More informationPATHOPHYSIOLOGY HS3410 RN-BSN, Spring Semester, 2016
PATHOPHYSIOLOGY HS3410 RN-BSN, Spring Semester, 2016 Pathophysiology, the altered physiology that results from deviations in health and wellness, explores the cellular alterations associated with changes
More informationClinical Review Criteria Related to Speech Therapy 1
Clinical Review Criteria Related to Speech Therapy 1 I. Definition Speech therapy is covered for restoration or improved speech in members who have a speechlanguage disorder as a result of a non-chronic
More informationPhysician Assistant Studies
The Graduate School Physician Assistant Studies / 343 Physician Assistant Studies http://www.siumed.edu/paprogram/ SCHOOL OF MEDICINE Graduate Faculty: Browning, Ronald, Clinical Instructor, Emeritus,
More informationInstrumentation, Control & Automation Staffing. Maintenance Benchmarking Study
Electronic Document Instrumentation, Control & Automation Staffing Prepared by ITA Technical Committee, Maintenance Subcommittee, Task Force on IC&A Staffing John Petito, Chair Richard Haugh, Vice-Chair
More informationAD (Leave blank) PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland
AD (Leave blank) Award Number: W81XWH-09-1-0282 TITLE: Georgetown University and Hampton University Prostate Cancer Undergraduate Fellowship Program PRINCIPAL INVESTIGATOR: Anna Riegel, PhD CONTRACTING
More informationApril 25-27, Cardiology in the Capital: Register Now! Case-Based Clinical Decision Making
Mayo School of Continuous Professional Development Cardiology in the Capital: Case-Based Clinical Decision Making April 25-27, 2013 Capital Hilton Washington, D.C. www.thecapitalhilton.com Course Directors
More informationPharmaceutical Medicine as a Specialised Discipline of Medicine
Pharmaceutical Medicine as a Specialised Discipline of Medicine Gerfried K.H. Nell Director, NPC Nell Pharma Connect Austria Slide 1 Pharmaceutical Medicine..is a medical scientific discipline concerned
More informationDeveloped by Dr. Carl A. Ferreri & Additional Concepts by Dr. Charles Krebs. Expanded by
Name Date Advanced I Workshop Manual Language Processing and Brain Integration Developed by Dr. Carl A. Ferreri & Additional Concepts by Dr. Charles Krebs Expanded by Dr. Mitchell Corwin 2914 Domingo Ave
More informationBoard of Directors OFFICERS. John B. Smith, Jr., MD, Chairman Physician
Financial Learning & Growth Customer Business Processes Board of Directors OFFICERS John B. Smith, Jr., MD, Chairman Charles T. Frock, Vice-Chairman Retired Hospital System Chief Executive Officer Roger
More informationName in full: Last First Middle. Telephone: Day Evening Social Security No.: Internship: Dates of Start and Completion. Name and Address of Hospital:
Jefferson Health System Check program for which you are applying Name in full: Last First Middle Present Mailing Address: E-mail: Telephone: Day Evening Social Security No.: Permanent Mailing Address:
More informationInternational Series in Operations Research & Management Science
International Series in Operations Research & Management Science Volume 240 Series Editor Camille C. Price Stephen F. Austin State University, TX, USA Associate Series Editor Joe Zhu Worcester Polytechnic
More informationUNIVERSITY OF ALABAMA AT BIRMINGHAM. IPEDS Completions Reports, July 1, June 30, 2016 SUMMARY
SUMMARY Degree Level 2006-07 2007-08 2008-09 2009-10 2010-11 2011-12 2012-13 2013-14 2014-15 2015-16* Certificates 12 21 16 16 17 22 20 21 18 15 Bachelor's 1814 1907 1916 1921 1997 1986 2195 2042 2165
More informationBiomedical Sciences (BC98)
Be one of the first to experience the new undergraduate science programme at a university leading the way in biomedical teaching and research Biomedical Sciences (BC98) BA in Cell and Systems Biology BA
More informationGUIDELINES FOR COMBINED TRAINING IN PEDIATRICS AND MEDICAL GENETICS LEADING TO DUAL CERTIFICATION
GUIDELINES FOR COMBINED TRAINING IN PEDIATRICS AND MEDICAL GENETICS LEADING TO DUAL CERTIFICATION PREAMBLE This document is intended to provide educational guidance to program directors in pediatrics and
More informationPULMONARY AND CRITICAL CARE TRAINING PROGRAMS
PULMONARY AND CRITICAL CARE TRAINING PROGRAMS DIVISION OF PULMONARY, CRITICAL CARE & SLEEP MEDICINE Harper University Hospital 3990 JOHN R Detroit, MI 48201 James A. Rowley, M.D. Program Director, Pulmonary/Critical
More informationUniversity of Kansas School of Medicine. Cardiopulmonary
University of Kansas School of Medicine Cardiopulmonary Module Director and Co-Directors John Wood, PhD jwood2@kumc.edu - Director Associate Professor, Departments of Molecular & Integrative Physiology
More informationFACTS. & Figures. University of Pennsylvania School of Medicine University of Pennsylvania Health System
FACTS & Figures University of Pennsylvania School of Medicine University of Pennsylvania Health System 2011 OVERVIEW Penn Medicine is among the most highly regarded academic medical centers in the world.
More informationLoyola University Chicago ~ Archives and Special Collections
Accession No.: UA1981.65, 1981.74 STRITCH SCHOOL OF MEDICINE OFFICE OF THE DEAN LOUIS DAVID MOORHEAD, M.D., RECORDS Dates: 1931-1940 Creator: Moorhead, Louis David (1892-1951) Extent: 2.5 linear feet Level
More informationGuide to Teaching Computer Science
Guide to Teaching Computer Science Orit Hazzan Tami Lapidot Noa Ragonis Guide to Teaching Computer Science An Activity-Based Approach Dr. Orit Hazzan Associate Professor Technion - Israel Institute of
More informationBIOH : Principles of Medical Physiology
University of Montana ScholarWorks at University of Montana Syllabi Course Syllabi Spring 2--207 BIOH 462.0: Principles of Medical Physiology Laurie A. Minns University of Montana - Missoula, laurie.minns@umontana.edu
More informationOffice: CLSB 5S 066 (via South Tower elevators)
Syllabus BI417/517 Mammalian Physiology Course Number: Bi 417 ~ Section 001 / CRN 60431 BI 517 ~ Section 001 / CRN 60455 Course Title: Mammalian Physiology Credits: 4 Term/Year: Spring 2016 Meeting Times:
More informationOur visiting specialists bring their expertise to you!
Our visiting specialists bring their expertise to you! Save yourself a drive! At Livingston HealthCare, we create partnerships with area experts to bring specialized care to you. Many visiting specialists
More informationESC Declaration and Management of Conflict of Interest Policy
ESC Declaration and Management of Conflict of Interest Policy The European Society of Cardiology (ESC) is dedicated to reducing the burden of cardiovascular disease and improving the standards of care
More informationResearch Output and Publications Impact of Postgraduate Institute of Medical Education and Research Chandigarh ( )
10.5005/jp-journals-10028-1030 ORIGINAL ARTICLE Research Output and Publications Impact of Postgraduate Institute of Medical Education and Research Chandigarh (1999-2008) Raj Kumar, BM Gupta, JS Thakur,
More informationContract Promotional Review Committee support for the Pharmaceutical Industry. Medical Affairs Regulatory Legal
Contract Promotional Review Committee support for the Pharmaceutical Industry Medical Affairs Regulatory Legal DISCUSSION TOPICS Situation Review Peer Review Institute Our Services Client Advantages Summary
More informationDetails of educational qualifications
Name of the Teacher: Name of the Department: Current post held: Associate Professor Date on which this format was filled (dd/mm/yyyy): 15/03/2017 Details of educational qualifications Qualification College
More informationAlyson D. Stover, MOT, JD, OTR/L, BCP
Alyson D. Stover, MOT, JD, OTR/L, BCP Curriculum Vitae BIOGRAPHICAL INFORMATION Business Address: Department of Occupational Therapy School of Health & Rehabilitation Sciences University of Pittsburgh
More informationMEDICAL COLLEGE OF WISCONSIN (MCW) WHO WE ARE AND OUR UNIQUE VALUE
MEDICAL COLLEGE OF WISCONSIN (MCW) WHO WE ARE AND OUR UNIQUE VALUE TO THE COMMUNITY Presented by John R. Raymond, Sr., MD President and CEO, MCW June 5, 2017 Agenda 1. Who We Are 2. MCW Financial Model
More informationConducting the Reference Interview:
Conducting the Reference Interview: A How-To-Do-It Manual for Librarians Second Edition Catherine Sheldrick Ross Kirsti Nilsen and Marie L. Radford HOW-TO-DO-IT MANUALS NUMBER 166 Neal-Schuman Publishers,
More informationSchool of Pharmacy & Pharmaceutical Sciences
School of Pharmacy & Pharmaceutical Sciences About Trinity Located in the heart of Dublin city and founded in 1592, Trinity College Dublin is an historic university making a modern impact. As Ireland s
More informationResponse to the Review of Modernising Medical Careers
Response to the Review of Modernising Medical Careers July 2007 The Academy of Medical Sciences The Academy of Medical Sciences promotes advances in medical science and campaigns to ensure these are converted
More informationNORMAL AND ABNORMAL DEVELOPMENT OF BRAIN AND BEHAVIOUR
NORMAL AND ABNORMAL DEVELOPMENT OF BRAIN AND BEHAVIOUR BOERHAAVE SERIES FOR POSTGRADUATE MEDICAL EDUCATION PROCEEDINGS OF THE BOERHAA VE COURSES ORGANIZED BY THE FACULTY OF MEDICINE, UNIVERSITY OF LEIDEN
More informationWhat can I learn from worms?
What can I learn from worms? Stem cells, regeneration, and models Lesson 7: What does planarian regeneration tell us about human regeneration? I. Overview In this lesson, students use the information that
More information2014 RDCR SYMPOSIUM AGENDA
2014 RDCR SYMPOSIUM AGENDA MONDAY 1300 SESSION 1: RDCR NEEDS ASSESSMENT 1300-1305 Introduction / Moderator Geir Strandenes, MD Senior Medical Officer Norwegian Naval Special Operation Commando Researcher,
More informationConstructing Blank Cloth Dolls to Assess Sewing Skills: A Service Learning Project
Journal of Family & Consumer Sciences Education, 28(2), 2010 Constructing Blank Cloth Dolls to Assess Sewing Skills: A Service Learning Project Holly Kihm Debbie Johnson Jamie Napolitano Southeastern Louisiana
More informationREGULATION RESPECTING THE TERMS AND CONDITIONS FOR THE ISSUANCE OF THE PERMIT AND SPECIALIST'S CERTIFICATES BY THE COLLÈGE DES MÉDECINS DU QUÉBEC
(This version is offered as a courtesy and holds no official value.) Professional Code (R.S.Q., c. C-26, s. 93, sub. c and c.1, 94 par. i and 94.1) DIVISION I GENERAL PROVISIONS 1. The purpose of this
More informationGERARD VAN SWIETEN AND HIS WORLD I 700-I 772
GERARD VAN SWIETEN AND HIS WORLD I 700-I 772 ARCHIVES INTERNATIONALES D'HISTOIRE DES IDEES INTERNATIONAL ARCHIVES OF THE HISTORY OF IDEAS FRANK T. BRECHKA GERARD VAN SWIETEN AND HIS WORLD 17 00-1 77 2
More informationManchester Academy for Healthcare Scientist Education STP OPEN DAY. MAHSE (http://mahse.co.uk/) Professor Phil Padfield.
STP OPEN DAY MAHSE (http://mahse.co.uk/) Professor Phil Padfield 7 th January 2016 What are Healthcare Scientists? Provide expert diagnostic advice and therapeutic care for the treatment of patients and
More informationEMORY UNIVERSITY. SCHOOL OF MEDICINE. Emory School of Medicine records,
EMORY UNIVERSITY. SCHOOL OF MEDICINE. Emory School of Medicine records, 1916-2016 Emory University Health Sciences Archives Woodruff Health Sciences Center Library 1462 Clifton Road, NE Atlanta, GA 30322
More informationUniversity of the Cumberlands Master of Science in Physician Assistant Studies Program
University of the Cumberlands Master of Science in Physician Assistant Studies Program PA Catalog and Policy Handbook 2016-2017 Contents PART I: GENERAL POLICIES AND PROCEDURES...6 INTRODUCTION... 7 PROGRAM
More information2016 Match List. Residency Program Distribution by Specialty. Anesthesiology. Barnes-Jewish Hospital, St. Louis MO
2016 Match List Residency Program Distribution by Specialty Anesthesiology Cleveland Clinic Foundation - Ohio, Cleveland OH University of Arkansas Medical School - Little Rock, Little Rock AR University
More informationThe College of New Jersey Department of Chemistry. Overview- 2009
The College of New Jersey Department of Chemistry Overview- 2009 Faculty Heba Abourahma John Allison Michelle Bunagan Lynn Bradley Benny Chan Don Hirsh Jinmo Huang David Hunt Stephanie Sen (plus currently
More informationLecture Notes on Mathematical Olympiad Courses
Lecture Notes on Mathematical Olympiad Courses For Junior Section Vol. 2 Mathematical Olympiad Series ISSN: 1793-8570 Series Editors: Lee Peng Yee (Nanyang Technological University, Singapore) Xiong Bin
More informationMedical College of Wisconsin and Froedtert Hospital CONSENT TO PARTICIPATE IN RESEARCH. Name of Study Subject:
IRB Approval Period: 03/21/2017 Medical College of Wisconsin and Froedtert Hospital CONSENT TO PARTICIPATE IN RESEARCH Name of Study Subject: Comprehensive study of acute effects and recovery after concussion:
More informationMARE Publication Series
MARE Publication Series Volume 8 Series Editors Maarten Bavinck University of Amsterdam, Amsterdam, The Netherlands Svein Jentoft Tromsø, Norway The MARE Publication Series is an initiative of the Centre
More informationTennessee Chapter Scientific Meeting
Tennessee Chapter Scientific Meeting 2017 October 27 28, 2017 Franklin Marriott Cool Springs Franklin, TN Register Online Today! Current Clinical Guidelines in Internal Medicine This live activity has
More informationBasic Standards for Residency Training in Internal Medicine. American Osteopathic Association and American College of Osteopathic Internists
Basic Standards for Residency Training in Internal Medicine American Osteopathic Association and American College of Osteopathic Internists BOT Rev. 2/2011 TABLE OF CONTENTS I. Introduction... 3 II Mission...
More informationTHE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON MCGOVERN MEDICAL SCHOOL CATALOG ADDENDUM
THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON MCGOVERN MEDICAL SCHOOL 2016-18 CATALOG ADDENDUM Index Page I. Mission II. Fees and Charges III. Curriculum IV. Pre-Entry Program Pages 7-8 CURRENT:
More informationNew Hampshire Chapter Scientific Meeting
New Hampshire Chapter Scientific Meeting 2017 October 27, 2017 Lyme Inn Lyme, New Hampshire Fostering Excellence in Internal Medicine This educational activity has been designated for 6 CME credits. Meeting
More informationUIC HEALTH SCIENCE COLLEGES
Academic Mission Report: Board of Trustees March 10, 2010 Joseph A. Flaherty, MD Dean, College of Medicine INNOVATION EXCELLENCE SERVICE Brief History 1858 Illinois Eye and Ear Infirmary opens 1859 College
More informationDear Members of the Biocenter
!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! April, 2014 / s.s., l.h. Dear Members of the Biocenter!! In
More informationAUTONOMY. in the Law
AUTONOMY in the Law Ius Gentium Comparative Perspectives on Law and Justice VOLUME 1 Series Editor Mortimer Sellers (University of Baltimore) Board of Editors Myroslava Antonovych (Kyiv-Mohyla Academy)
More information2015 / Critical Care Medicine Fellowship Program. heal. serve. educate. To serve, to heal and to educate
2015 / 2016 Critical Care Medicine Fellowship Program serve heal educate To serve, to heal and to educate Welcome Thank you for your interest in the Critical Care Medicine Fellowship Program at Cooper
More informationUS and Cross-National Policies, Practices, and Preparation
US and Cross-National Policies, Practices, and Preparation Studies in Educational Leadership VOLUME 12 Series Editor Kenneth A. Leithwood, OISE, University of Toronto, Canada Editorial Board Christopher
More informationCourse Selection for Premedical Students (revised June 2015, with College Curriculum updates)
Course Selection for Premedical Students (revised June 2015, with College Curriculum updates) Premedical students can choose any major, and many of the courses that an individual premedical student takes
More informationPRODUCT PLATFORM AND PRODUCT FAMILY DESIGN
PRODUCT PLATFORM AND PRODUCT FAMILY DESIGN PRODUCT PLATFORM AND PRODUCT FAMILY DESIGN Methods and Applications Edited by Timothy W. Simpson 1, Zahed Siddique 2, and Jianxin (Roger) Jiao 3 1 The Pennsylvania
More informationCOMMUNICATION-BASED SYSTEMS
COMMUNICATION-BASED SYSTEMS COMMUNICATION-BASED SYSTEMS Proceedings of the 3rd International Workshop held at the TU Berlin, Germany, 31 March - 1 April 2000 Edited by GÜNTER HOMMEL Technische Universität
More informationPerspectives of Information Systems
Perspectives of Information Systems Springer-Science+ Business Media, LLC Vesa Savolainen Editor and Main Author Perspectives of Information Systems Springer Vesa Savolainen Department of Computer Science
More informationCourse outline. Code: LFS303 Title: Pathophysiology
Course outline Code: LFS303 Title: Pathophysiology Faculty of: Science, Health, Education and Engineering Teaching Session: Semester 1 Year: 2017 Course Coordinator: Dr Nicole Reinke Email: nreinke@usc.edu.au
More informationCase Study Physiology
Case Free PDF ebook Download: Case Download or Read Online ebook case study physiology in PDF Format From The Best User Guide Database Jul 28, 2006 - Some students in Human Anatomy and have little Students
More informationLife Sciences. Our Services. Bereskin & Parr LLP bereskinparr.com
Life Sciences Advances in life sciences create new and exciting business opportunities. The protection and enforcement of intellectual property rights is critical to making the most of those opportunities.
More informationLecture Notes in Artificial Intelligence 4343
Lecture Notes in Artificial Intelligence 4343 Edited by J. G. Carbonell and J. Siekmann Subseries of Lecture Notes in Computer Science Christian Müller (Ed.) Speaker Classification I Fundamentals, Features,
More informationDr. Isadore Dyer, Association of American Medical Colleges
Fall/Winter 2013 Volume 60, Number 2 Examiner National Board of Medical Examiners 3750 Market Street Philadelphia, PA 19104-3102 www.nbme.org NBME Plans Its 100th Annual Meeting On May 5, 2015, the NBME
More informationMOUNT ROGERS COMMUNITY SERVICES BOARD LOCAL HUMAN RIGHTS COMMITTEE MINUTES
MOUNT ROGERS COMMUNITY SERVICES BOARD LOCAL HUMAN RIGHTS COMMITTEE MINUTES May 14, 2013 The Mount Rogers Local Human Rights Committee met on Tuesday, May 14, 2013 in the E. W. Cline, Jr. Building in Wytheville,
More informationDr. Tang has been an active member of CAPA since She was Co-Chair of Education Committee and Executive committee member ( ).
2015 CAPA Candidates Profiles For President-elect (alphabetic order): Dr. Ping Tang Dr. Ping Tang is a Professor at Department of Pathology and Laboratory Medicine, University of Rochester Medical Center,
More informationTo link to this article: PLEASE SCROLL DOWN FOR ARTICLE
This article was downloaded by: [Dr Brian Winkel] On: 19 November 2014, At: 04:59 Publisher: Taylor & Francis Informa Ltd Registered in England and Wales Registered Number: 1072954 Registered office: Mortimer
More informationBIOMEDICAL ENGINEERING, B.S.
Biomedical Engineering, B.S. 1 BIOMEDICAL ENGINEERING, B.S. Biomedical engineering (BME) is the application of engineering tools for solving problems in biology and medicine. It is an engineering discipline
More informationERNEST MARIO SCHOOL OF PHARMACY
ERNEST MARIO SCHOOL OF PHARMACY Information on the following subjects may be found in the General Information section at the back of this catalog: Student Life and Services, Admission, Tuition and Fees,
More informationE35 RE-DISCOVER CAREERS AND EDUCATION THROUGH 2020
E35 RE-DISCOVER CAREERS AND EDUCATION THROUGH 2020 MICHELE BROWN, OAKTON COMMUNITY COLLEGE JULIE MARLATT, COLLEGE OF DUPAGE DEBBIE MICHELINI, COLLEGE OF LAKE COUNTY COMMUNITY COLLEGE STATS 6 million students
More informationElectron Configuration Multiple Choice Questions
Electron Configuration Free PDF ebook Download: Electron Configuration Download or Read Online ebook electron configuration multiple choice questions in PDF Format From Best User Guide Database A. Which
More informationDepartment of Anatomy and Cell Biology Curriculum
Department of Anatomy and Cell Biology Curriculum The graduate program in Anatomy and Cell Biology prepares the student for a research and/or teaching career with concentrations in one or more of the following:
More informationJoint Board Certification Project Team
in Optometry: Framework Initial Report of the January 27, 2009 JBCPT Mission Statement Develop and propose an attainable, credible and defensible model for in Optometry and maintenance of certification
More informationImproving recruitment, hiring, and retention practices for VA psychologists: An analysis of the benefits of Title 38
Improving recruitment, hiring, and retention practices for VA psychologists: An analysis of the benefits of Title 38 Introduction / Summary Recent attention to Veterans mental health services has again
More informationMMOG Subscription Business Models: Table of Contents
DFC Intelligence DFC Intelligence Phone 858-780-9680 9320 Carmel Mountain Rd Fax 858-780-9671 Suite C www.dfcint.com San Diego, CA 92129 MMOG Subscription Business Models: Table of Contents November 2007
More informationNanotechnology STEM Program via Research Experience for High School Teachers
Nanotechnology STEM Program via Research Experience for High School Teachers Mangilal Agarwal 1,*, Qurat-ul-Ann Mirza 3, 7, Joseph Bondi 3, 7, Brandon Sorge 3, Maher Rizkalla 1,4, Richard Ward 2, Corbin
More informationIntroduction. One-Year versus Two-Year Program
The Massachusetts Eye & Ear Infirmary Cornea, Refractive Surgery, and External Disease Fellowship Program Harvard Medical School Department of Ophthalmology Introduction The Cornea Service of the Massachusetts
More informationPerioperative Care of Congenital Heart Diseases
CALL FOR APPLICATIONS DR 617/2017 II LEVEL MASTER Perioperative Care of Congenital Heart Diseases Academic Year 2017/2018 2018/2019 In collaboration with Fondazione G. Monasterio Regione Toscana CNR Article
More informationCommunication and Swallowing Changes in Healthy Aging Adults
76565_FMxx_FINAL.QXP 4/6/10 4:19 PM Page i Jones & Bartlett Learning, LLC. NOT FOR SALE OR DISTRIBUTION Communication and Swallowing Changes in Healthy Aging Adults Angela N. Burda, PhD, CCC-SLP Associate
More informationTools to SUPPORT IMPLEMENTATION OF a monitoring system for regularly scheduled series
RSS RSS Tools to SUPPORT IMPLEMENTATION OF a monitoring system for regularly scheduled series DEVELOPED BY the Accreditation council for continuing medical education December 2005; Updated JANUARY 2008
More informationUniversity of Southern California Hayward R. Alker Postdoctoral Fellow, Center for International Studies,
JORDAN BRANCH Department of Political Science Box 1844, 36 Prospect Street Providence, RI 02912 jordan_branch@brown.edu CURRENT POSITION Assistant Professor, Department of Political Science, 2012 present
More informationPROGRAM REQUIREMENTS FOR RESIDENCY EDUCATION IN DEVELOPMENTAL-BEHAVIORAL PEDIATRICS
In addition to complying with the Program Requirements for Residency Education in the Subspecialties of Pediatrics, programs in developmental-behavioral pediatrics also must comply with the following requirements,
More informationAnMed Health Family Medicine Residency Program Curriculum and Benefits
AnMed Health Family Medicine Residency Program Curriculum and Benefits Residents receive medical, dental and life insurance benefits. Resident salaries range from $55,500 to $58,000, depending on the year
More informationInternational Journal of Innovative Research and Advanced Studies (IJIRAS) Volume 4 Issue 5, May 2017 ISSN:
Effectiveness Of Using Video Presentation In Teaching Biology Over Conventional Lecture Method Among Ninth Standard Students Of Matriculation Schools In Coimbatore District Ms. Shigee.K Master of Education,
More informationDana Carolyn Paquin Curriculum Vitae
Dana Carolyn Paquin Curriculum Vitae Education 2007 Ph.D., Mathematics, Stanford University. Thesis: Multiscale methods for image registration. 2002 B.S., Mathematics (Magna Cum Laude), Davidson College.
More informationMaximizing Learning Through Course Alignment and Experience with Different Types of Knowledge
Innov High Educ (2009) 34:93 103 DOI 10.1007/s10755-009-9095-2 Maximizing Learning Through Course Alignment and Experience with Different Types of Knowledge Phyllis Blumberg Published online: 3 February
More informationJames H. Walther, Ed.D.
James H. Walther, Ed.D. Curriculum Vitae Emporia State University School of Library and Information Management (SLIM) Campus Box 4025 1 Kellogg Circle Emporia, KS 66801-5415 Phone: 620-341-5698 Email:
More informationOVERVIEW TARGET AUDIENCE OBJECTIVES PLALNNING PLANNING COMMITEE
OVERVIEW The purpose of this conference is to update physicians, scientists, nurses and other healthcare professionals, trainees, and the general public in the greater Midwest region on: 1) the past, present,
More informationMaster's Programme Biomedicine and Biotechnology
Master's Programme Biomedicine and Biotechnology Translation of the curriculum, published June 2 nd, 2009 in the bulletin ( Mitteilungsblatt ) of the University of Veterinary Medicine, Vienna. University
More informationJeff Walker Office location: Science 476C (I have a phone but is preferred) 1 Course Information. 2 Course Description
BIO 221 Human Physiology I Jeff Walker Office location: Science 476C E-mail: walker@maine.edu (I have a phone but e-mail is preferred) Fall 2017 1 Course Information Room Science 105 Class meetings are
More informationStatus of the MP Profession in Europe
Status of the MP Profession in Europe John Damilakis, MSc, PhD Prof. of Medical Physics Faculty of Medicine University of Crete, Greece IOMP Chair, E&T Committee EFOMP Vice-President (2014) Basic education:
More informationTexas Bioscience Institute Educating Scientists For The Future. Nelda Howton
Texas Bioscience Institute Educating Scientists For The Future Nelda Howton www.texasbioscienceinstitute.com Nov. 20, 2007 Impact of the Health Care Industry Temple is home to three hospitals and the Texas
More informationAcademic Catalog
Academic Catalog 2017-2018 August 1, 2017 Page 1 TABLE OF CONTENTS INTRODUCTION... 4 Mission... 4 Philosophy... 5 Core Competencies... 6 ACADEMIC PROGRAM... 6 Graduation Requirements for a Ph.D. Degree...
More informationCurriculum Vitae of. JOHN W. LIEDEL, M.D. Developmental-Behavioral Pediatrician
Updated July 07, 2009 of JOHN W. LIEDEL, M.D. Developmental-Behavioral Pediatrician EDUCATIONAL AND PROFESSIONAL EXPERIENCE: Children's Program 7707 SW Capitol Hwy. 97219 August 1987 - Present The Children's
More informationKUTZTOWN UNIVERSITY KUTZTOWN, PENNSYLVANIA COE COURSE SYLLABUS TEMPLATE
KUTZTOWN UNIVERSITY KUTZTOWN, PENNSYLVANIA COE COURSE SYLLABUS TEMPLATE DEPARTMENT OF SECONDARY EDUCATION I. Course Description: Course Prefix, Number and Title Secondary Education SEU 520 Education Theory
More informationPostdoctoral Fellow, Department of Pharmacology and Toxicology, Medical College of Wisconsin Research Advisor: William B.
PHILLIP G. KOPF, PHD ASSISTANT PROFESSOR, MIDWESTERN UNIVERSITY Department of Pharmacology Chicago College of Osteopathic Medicine Midwestern University 555 31 st Street Downer s Grove, IL 60515 Work:
More informationNUTRITIONAL SCIENCE (H SCI)
Nutritional Science (H SCI) 1 NUTRITIONAL SCIENCE (H SCI) Nutritional science looks at the connection between diet and health. Students learn how diet can play a crucial role in the cause, treatment, and
More informationMaster s Programme Comparative Biomedicine
Master s Programme Comparative Biomedicine Infection Biomedicine and Tumour Signalling Pathways Translation of the curriculum, published on July 1, 2015, at the University of Veterinary Medicine, Vienna
More informationTHE UNIVERSITY OF THE WEST INDIES
THE UNIVERSITY OF THE WEST INDIES CAVE HILL CAMPUS THE FACULTY OF MEDICAL SCIENCES GRADUATE PROGRAMME REGULATIONS AND SYLLABUSES 2014-2015 WWW.CAVEHILL.UWI.EDU/GRADSTUDIES Every attempt has been made to
More information