2017 Global Brain Health and Performance Summit

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1 Presented by Neurological Institute and the Stanley D. and Joan H. Ross Center for Brain Health and Performance GLOBAL BRAIN HEALTH AND PERFORMANCE SUMMIT 1 EXPLORING THE LATEST DISCOVERIES AND INNOVATIONS: LINKING BRAIN HEALTH TO PERFORMANCE, RECOVERY, HEALING AND WELLNESS 2017 Global Brain Health and Performance Summit April Hilton Columbus Downtown Learn more at go.osu.edu/brainhealth

2 2 Global Brain Health and Performance Summit EXPLORING THE LATEST DISCOVERIES AND INNOVATIONS: LINKING BRAIN HEALTH TO PERFORMANCE, RECOVERY, HEALING AND WELLNESS April 27-29, 2017 Hilton, Columbus Downtown Presented by Wexner Medical Center Neurological Institute Stanley D. and Joan H. Ross Center for Brain Health and Performance Advances in neuroscience are dramatically expanding our understanding of the brain and how it influences our bodies and all aspects of our lives. New technologies can measure and quantify the links between the brain, nervous system and our body function in ways that would have been inconceivable only a few years ago. From the football field to the battlefield to the boardroom, cutting-edge brain research and sophisticated technology are coming together to produce innovative tools that have the potential to optimize brain health, performance, recovery and function. Join our experts as they discuss the latest advancements in neuroscience and technological advances for understanding brain health, including: Neurotechnology Brain-body physiology and performance Virtual reality, neurogaming, artificial intelligence and simulation Sensor technology Industry, nonprofit, academic, and media perspectives on the definition of brain health and its growing impact on society Assessments Big data analytic applications to neuroscience Augmentation and therapeutic strategies Global ecosystems of brain health Brain-body connection and physical performance Inflammation and the brain-body connection Lifestyle factors impacting brain health

3 GLOBAL BRAIN HEALTH AND PERFORMANCE SUMMIT 3 Attendees Attendees include neuroscientists and physiologists, physicians, psychologists, sports scientists, nurses, nutritionists, social workers, athletes and coaches, military personnel, digital technology experts, entrepreneurs, engineers and technology innovators from around the globe. At the Summit, attendees will have the opportunity to: Learn about the latest technologies and approaches to improve our understanding of brain-body connectivity, health and performance metrics Discuss methods of optimizing brain health and performance. Examine how factors such as sleep, stress, exercise, age, inflammation, and nutrition impact brain-body function and performance Explore new methodologies for examining cognitive functioning across a variety of populations including, athletes, military, general population, and individuals with disease or injury Stanley D. and Joan H. Ross Center for Brain Health and Performance Summit Planning Committee ALI R. REZAI, MD Director, Ross Center for Brain Health and Performance Director, The Ohio State Neurological Institute Associate Dean, Neuroscience JENNIFER BOGNER, PhD, ABPP Professor, Physical Medicine and Rehabilitation Division Director, Rehabilitation Psychology Vice-Chair of Research and Academic Affairs JESSICA BUSKIRK, MBA Director of Operations Ross Center for Brain Health and Performance JOHN CORRIGAN, PhD, ABPP Director, Knowledge Translation, Ross Center for Brain Health and Performance Emeritus Professor, Physical Medicine and Rehabilitation Director, Ohio Valley Center for Brain Injury and Prevention SCOTT GALSTER, PhD Senior Advisor, Ross Center for Brain Health and Performance Lead, Outreach and Collaboration Programs, Senior International Focal Point, Airman Systems Directorate, Air Force Research Laboratory, Wright- Patterson Air Force Base CHELSEA KANE, PsyD Director, Outreach and Communications, Ross Center for Brain Health and Performance Post-Doctoral Fellow, Physical Medicine and Rehabilitation JANICE KIECOLT- GLASER, PhD Distinguished Professor, Psychiatry, Psychology, Health Behavior and Health Promotion Director, Institute for Behavioral Medicine Research ULYSSES MAGALANG, MD Professor, Pulmonary, Allergy, Critical Care and Sleep Medicine and Neuroscience Director, Sleep Disorders Program RANDY NELSON, PhD Distinguished Professor, Psychology and Neuroscience Chair, Department of Neuroscience Co-Director, Neuroscience Research Institute JANINE OMAN, MS, PT/AT Associate Athletic Director, Department of Athletics JAN SCHWAB, MD, PhD Professor, Neurology, Physical Medicine and Rehabilitation and Neuroscience PER SEDERBERG, PhD Chief Scientist, Ross Center for Brain Health and Performance Associate Professor, Psychology, Cognitive Area KYLE TRAVER, MS Director, Research and Development, Ross Center for Brain Health and Performance Program Manager, Applied Neuroscience Branch, Airman Systems Directorate, 711 Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base

4 4 Presenters Keynote, plenary and breakout sessions will feature top scientists from academia, industry and government to discuss innovations in research and development designed to enhance brain health and human performance. Keynote Speakers Deepak Chopra, MD Pioneer and Advocate in Integrative Medicine Dan Buettner National Geographic Fellow, Author of Thrive, The Blue Zones and The Blue Zones Solution Nathan Price, PhD Institute for Systems Biology (ISB), 100K Wellness Project Plenary & Featured Speakers JEREMY ABBATE Scientific American, Publisher PETE EDWARDS JR., MD Columbus Crew, Team Physician SCOTT GRAFTON, MD University of California Santa Barbara, Professor and Presidential Chair of Neuroscience MICHAEL APUZZO, MD The Ohio State University Adjunct Professor, Neurological Surgery Senior Consultant, Neurological Institute Honorary Degree, Doctor of Science MOSHE BAR, PhD Bar-Ilan University, Harvard University, Isreal Brain Technologies CHRISTOPHER COBURN, MPA Partners HealthCare, Chief Innovation Officer NAOMI EISENBERGER, PhD University of California, Professor Social Psychology ELLEN FRANK, PhD HealthRhythms, Co-Founder and Chief Scientific Officer ANDREW FREEDMAN Mashable, Science Editor RICHARD FRIEDMAN, PhD Weill Cornell Medical College, Professor of Clinical Psychiatry JOSH HAGEN, PhD Air Force Research Laboratory, Head of STRONG Team JON HAMILTON NPR, Science Correspondent ADAM HANINA, MBA AiCure CEO and Co-Founder AMIR KALALI, MD Quintiles IMS, Head of Neuroscience Center of Excellence / University of California San Diego, Professor

5 GLOBAL BRAIN HEALTH AND PERFORMANCE SUMMIT 5 WILLIAM KRAEMER, PhD The Ohio State University, Professor of Kinesiology ANDREW MILLER, MD Emory University, Director, Adult Outpatient Psychiatry STEPHEN KENNEDY SMITH, MEd, JD Pear Therapeutics, Co-Founder ARTHUR KRAMER, PhD Northeastern University, Professor and Senior Vice Provost MATT KUCHAN, PhD Abbott, Science Lead, Center for Nutrition, Learning and Memory JAMES OLDS, PhD National Science Foundation, Assistant Director for the Directorate for Biological Science RUCHIKA PRAKASH, PhD The Ohio State University, Professor of Psychology MORLEY STONE, PhD Air Force Research Laboratory, Chief Technology Officer STEVE TASHJIAN, MPT, CSCS Columbus Crew, High Performance Director MARK KVAMME Drive Capital, Partner HARALD PRUESS, MD Charité Universitätsmedizin, Campus Mitte Berlin, Neurology-Attending JEFFREY WADSWORTH, PhD Battelle, CEO SARAH LENZ LOCK, JD AARP, Executive Director of the Global Council on Brain Health ABBY LEVY, MBA Thrive Global, President ASHISH RAJ, PhD Cornell University, Assistant Professor of Neuroscience / BrainWire, CEO TOM RYAN The Ohio State University, Head Wrestling Coach KEVIN WASSERSTEIN, MS, MBA Neurotechnology Innovations Translator (NIT), Co-Founder BRETT WINGEIER, PhD Halo Neuroscience, Chief Technology Officer CLAY MARSH, MD West Virginia University, Vice President and Executive Dean for Health Sciences LT. COL. STEPHEN SAVELL Air Force Research Laboratory, Commander, 350 TS ANDREA SERINO, PhD MindMaze, Head Scientist / Swiss Federal Institute of Technology in Lausanne PHYLLIS ZEE, MD, PhD Northwestern University, Professor / Associate Director, Center for Sleep and Circadian Biology

6 6 AGENDA To learn more and register visit go.osu.edu/brainhealth. Thursday, April 27 Plenary Session 1: The Global Ecosystem of Brain Health Moderator: Jeremy Abbate, Scientific American 4 p.m. 4:15 p.m. Opening Address Putting Brain Health on the Public Agenda Ali Rezai, MD Neurological Institute, Director 4:30 p.m. Roundtable Discussion: What is Brain Health? Moderator: Jeremy Abbate Scientific American, Publisher Moshe Bar, PhD Bar-Ilan University Christopher Coburn, MPA Partners HealthCare Richard Friedman, PhD Cornell University Sarah Lenz Lock, JD AARP James Olds, PhD National Science Foundation 5:30 p.m. 5:35 p.m. 6 p.m. KEYNOTE INTRODUCTION KEYNOTE: Population Studies: Applications to Brain Health Roundtable Discussion: Population Brain Health Studies Moderator: Jon Hamilton NPR K. Craig Kent, MD College of Medicine, Dean Nathan Price, PhD Institute for Systems Biology (ISB) Amir Kalali, MD QuintilesIMS Clay Marsh, MD West Virginia University Nathan Price, PhD Institute for Systems Biology (ISB) 6:30 p.m. Brain Health Hero Award 6:45 p.m. Opening Reception

7 GLOBAL BRAIN HEALTH AND PERFORMANCE SUMMIT 7 Friday, April 28 Plenary Session 2: Technological Advances for Understanding Brain Health Moderator: Per Sederberg, PhD 7:30 a.m. 8:00 a.m. 8:05 a.m. 8:25 a.m. 8:45 a.m. 9:05 a.m. 9:25 a.m. 9:45 a.m. Breakfast Welcome Partnering in Cutting Edge Neurotechnology Brain Connectivity Models Cortical Control of the Autonomic Nervous System Measuring Mechanisms of Brain Activity Plenary Panel Discussion Michael Apuzzo, MD Jeffrey Wadsworth, PhD Battelle Ashish Raj, PhD Cornell University Scott Grafton, MD University of California Moshe Bar, PhD Bar-Ilan University, Harvard University Moderator: Per Sederberg, PhD Morning Break

8 8 Friday, April 28 Plenary Session 3: Brain-Body Connection and Physical Performance Moderator: Scott Galster, PhD, 10:10 a.m. The Harry T. Mangurian, Jr. Foundation Lecture*: Athletic Applications Josh Hagen, PhD William Kraemer, PhD 10:30 a.m. Third Offset Morley Stone, PhD 10:50-11:05 a.m. Military Applications State of the Science Military Applications Lt. Col. Stephen Savell 11:10 a.m. Performance Roundtable: Josh Hagen, PhD Morley Stone, PhD Moderator: Andrew Freedman Mashable Moderator: Scott Galster, PhD William Kraemer, PhD Tom Ryan The Ohio State Head Wrestling Coach Steve Tashjian, MPT, CSCS Columbus Crew Lt. Col. Stephen Savell 11:30 a.m. 11:35 a.m. 12:10 p.m. KEYNOTE INTRODUCTION KEYNOTE: Blue Zones: Secrets of a Long Life Sheldon M. Retchin, MD, MSPH, Chief Executive Officer, Ohio State Wexner Medical Center Dan Buettner National Geographic Lunch 1 p.m. Brain Health Commercialization Panel Christopher Coburn, MPA Partners HealthCare Brett Wingeier, PhD Halo Neuroscience Moderator: Jeremy Abbate Scientific American Abby Levy, MBA Thrive Global Kevin Wasserstein, MS, MBA Neurotechnology Innovations Translator (NIT) Mark Kvamme Drive Capital, Partner Andrea Serino, PhD MindMaze, Swiss Federal Institute of Technology in Lausanne 1:45 p.m. Digitizing Neuroscience: Research & Development Moderator: Amir Kalali, MD QuintilesIMS Ellen Frank, PhD HealthRhythms Adam Hanina, MBA AiCure Stephen Kennedy Smith, MEd, JD Pear Therapeutics 2:30-3 p.m. Break *The Harry T. Mangurian, Jr. Foundation, a Fort Lauderdale-based private foundation, supports medical and neurological research programs throughout the country, including Wexner Medical Center Neurological Institute.

9 GLOBAL BRAIN HEALTH AND PERFORMANCE SUMMIT 9 Friday, April 28 Sense, Assess & Augment Breakouts: 3 p.m.-5:45 p.m. The breakout sessions will be structured around the Sense, Assess and Augment framework with sessions dedicated to each element. Sense: Examines current and emerging technologies which allow for detection of functional states Assess: Focuses on big data analytic approaches to extract meaningful information from the data gathered from sensing activities. Augment: Showcases strategies, techniques and technology to optimize performance, health and readiness based on sense and assess findings. Breakout Session 1: 3:00 p.m. Sense Moderators: Kyle Traver, MS, Air Force Research Lab Bart Barthelemy, PhD, Wright Brothers Institute Advances in Sweat Sensing Jason Heikenfeld, PhD Eccrine Systems, Inc. Neuroprosthetic Body Awareness: Sensing through the Eyes of a Brain-Computer Interface Marcia Bockbrader, MD, PhD Leveraging Big Data to Build Better Neuroprosthetics David Friedenberg, PhD Battelle Non-invasive Physio Sensing Technologies John Bell, PhD Michigan State University Noninvasive Monitoring of Intracranial Hemorrhage George Shaw, PhD Sense Diagnostics, LLC Assess Moderators: Per Sederberg, PhD, Scott Galster, PhD, Air Force Research Lab Artificial Neural Networks Kevin Durkee Aptima, Inc. Extended Kalman Filtering Mingjun Zhang, PhD Endocrine-Brain Connections William Kraemer, PhD Biomarkers of Stress and Performance: Special Operations Regina Shia, PhD Fused Model Approaches for Assessment Omid Dehzangi, PhD University of Michigan Break: 4:15 p.m. Augment Moderator: Ashwini Sharan, MD Thomas Jefferson University Virtual Reality Bruno Herbelin, PhD Swiss Federal Institute of Technology in Lausanne Advances in Transcranial Direct Current Stimulation Andy McKinley, PhD Examining Modifiable Factors to Prevent Post-op Cognitive Decline Michelle Humeidan, MD, PhD Neuroprosthetics-enabled Cortical Control of a Paralyzed Hand: From Restoring Individual Finger Movements to Functional Grasps Gaurav Sharma, PhD Battelle DARPA RAM: Developing Neurostimulation Therapies for Patients with Memory Disorders Daniel Rizzuto, PhD University of Pennsylvania

10 10 Breakout Session 2: 4:30 p.m. Special Lectures Moderators: John Corrigan, PhD Chelsea Kane, PsyD Assess Moderators: Kevin Durkee, Aptima Mingjun Zhang, PhD, DSc, Augment Moderators: TBD Schulte Lecture* The Cognitive Revolution Per Sederberg, PhD Elaborate Interactions Between the Immune and Nervous systems Jan Schwab, MD, PhD Mindfulness Meditation for Behavioral Disorders and Chronic Pain Stephanie Lopez, LISW-S Integrative Restoration Institute Schulte Lecture* Consistent Variability in Motor Recovery Lynne Gauthier, PhD Schulte Lecture* Sleep & Light Uly Magalang, MD Arts & Rehabilitation Roundtable Chronic Brain Injury Discovery Theme Moderator: Lise Worthen-Chaudhari, MFA, MS, CSC Panelists: Jim Phelan, PhD, Jerry Mysiw, MD, Yune Lee, PhD, Eugenia Costa-Giomi, PhD, Kyle Sebastian fmri Modeling of Functional Brain Connectivity Scott Grafton, MD University of California Santa Barbara Concussion Spotting in Intercollegiate and Professional Athletics Jason Eckerle HRV Wearables and the Future of Healthcare Ron Gharbo, DO Eastern Virginia Medical School Cranial Cloud Pierre-Francois D Haese, PhD Vanderbilt University Poster Reception: 5:45 p.m. Treating Military PTSD Stephanie Lopez, LISW-S Integrative Restoration Institute Sports Performance Roundtable Moderator: Janine Oman, Department of Athletics Steve Tashjian, MPT, CSCS Columbus Crew Pete Edwards Jr., MD Columbus Crew Tom Ryan Michael Apuzzo, MD Christopher Kaeding, MD Josh Hagen, PhD Air Force Research Lab *The Rudi Schulte Research Institute (RSRI), a 501c(3) charitable foundation located in Santa Barbara, California, was founded in 1974 by its namesake whose many inventions included the shunt for hydrocephalus. RSI has a long history of promoting better treatment for hydrocephalus, as well as other groundbreaking research on the intersection of technology and brain function.

11 GLOBAL BRAIN HEALTH AND PERFORMANCE SUMMIT 11 Saturday, April 29 Plenary Session 4: Inflammation and the Brain-Body Connection Moderator: Janice Kiecolt-Glaser, PhD, 7:30 a.m. 8:00 a.m. 8:05 a.m. 8:25 a.m. Breakfast Welcome Depression, Inflammation and Cognition Immune Dysfunction and the Effects on Cognition Scott Galster, PhD Andrew Miller, MD Emory University Harald Pruess, MD Charité Universitätsmedizin, Campus Mitte Berlin 8:45 a.m. 9:05 a.m. 9:25 a.m. Inflammation and Consequences for Mood and Cognition Plenary Panel Discussion Naomi Eisenberger, PhD University of California Los Angeles Moderator: Janice Kiecolt-Glaser, PhD Morning Break

12 12 Saturday, April 29 Plenary Session 5: Lifestyle and Brain Health, Moderator: Ali Rezai, MD, 9:55 a.m. 10:15 a.m. Exercise and Cognition Nutrition Arthur Kramer, PhD Northeastern University, Senior Vice Provost Matt Kuchan, PhD Abbott 10:35 a.m. 10:55 a.m. 11:15 a.m. 11:35 a.m. 11:40 a.m. 12:20 p.m. Circadian Alignment and Sleep Meditation, Mindfulness and Augmentation Plenary Panel Discussion KEYNOTE INTRODUCTION KEYNOTE Closing Discussion Moderator: Andrew Freedman Mashable Phyllis Zee, MD, PhD Northwestern University Ruchika Prakash, PhD Moderator: Ali Rezai, MD Neurological Institute Michael Drake, MD, President Deepak Chopra, MD Integrative Medicine Pioneer Deepak Chopra, MD Integrative Medicine Pioneer Ruchika Prakash, PhD Ali Rezai, MD Neurological Institute 1:00 p.m. Summit Adjourns This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of CME Outfitters, LLC and Ohio State University Stanley D. and Joan H. Ross Center for Brain Health and Performance. CME Outfitters, LLC is accredited by the ACCME to provide continuing medical education for physicians. CME Outfitters, LLC designates this live activity for a maximum of AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity Ohio State Sports Medicine (BOC AP # P647) is approved by the Board of Certification, Inc. to offer provide continuing education to Athletic Trainers. This program is eligible for a maximum of 14 Category A CEU s. AT s should claim only those hours actually spent on the educational program.

13 GLOBAL BRAIN HEALTH AND PERFORMANCE SUMMIT 13 Register Now Visit go.osu.edu/brainhealth to register. Return Rate Regular Rate Industry Professional $495 $550 Physician/Scientist/Allied Health Professional/Nurse $295 $350 Ohio State Physician/Scientist/Allied Health Professional/Nurse $195 $250 Student/Resident Fellow $150 $200 Ohio State Student/Resident Fellow $95 $150 Single Day Pass $100 Group discounts available: Register three individuals from the same practice and receive a fourth registration free. Please contact brainhealthinfo@cbc-us.com for a registration code.

14 14 Hotel Hilton Columbus Downtown 401 N. High St. Columbus, OH Attendees of Global Brain Health and Performance Summit are offered a discounted room rate of $165 per night (plus tax and valet parking), single/double occupancy. Visit the Summit website to book your room or call the hotel at and use the group block code OSUMED.

15 GLOBAL BRAIN HEALTH AND PERFORMANCE SUMMIT 15 The Global Brain Health and Performance Summit Gratefully Acknowledges our Exhibitors and Supporters: AIHS Battelle Clint The Harry T. Mangurian, Jr. Foundation Inspire Medical Systems, Inc Medtronic Omega Laboratories Brain Injury Discovery Theme Rudi Schulte Research Institute (RSRI) Stanley D. and Joan H. Ross Center for Brain Health and Performance This program is made possible because of the generous support of Stan and Jodi Ross and their funding of the Stanley D. and Joan H. Ross Center for Brain Health and Performance. The mission of the Ross Center for Brain Health and Performance is to optimize health and performance by revolutionizing the understanding of the brain.

16 16 EXPLORING THE LATEST DISCOVERIES AND INNOVATIONS: LINKING BRAIN HEALTH TO PERFORMANCE, RECOVERY, HEALING AND WELLNESS go.osu.edu/cbhp

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