Resources for Career Success at CUMC
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1 Resources for Career Success at CUMC Melissa D. Begg, ScD Professor & Vice Dean for Education, Mailman School of Public Health Co-Director, Irving Institute for Clinical and Translational Research November 2013
2 What is the CTSA? A national consortium of medical research institutions, funded through NIH s Clinical and Translational Science Awards (CTSAs), working together and sharing a common vision to: Improve the conduct of biomedical research across the country Reduce the time it takes for laboratory discoveries to become treatments for patients Engage communities in clinical research Train a new generation of clinical and translational researchers There are about 60 funded centers
3 From the CTSA Fact Sheet: g/docs/ctsa_factsheet.pdf
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5 What is the Columbia CTSA? Columbia CTSA = IRVING INSTITUTE OVERALL GOALS: To transform the culture of research to accelerate the discovery and implementation of new treatments and prevention strategies. Key words: Interdisciplinary Translational Community-engaged
6 Goal: Improve the Research Process Idea Design Prepare Disseminate Analyze Execute
7 What are the components of the Irving Institute? Facilities: The 10 th floor of 2 contiguous buildings (PH and Harkness) Adult inpatient and outpatient units Administrative suite Bionutrition unit with research kitchen Biomarkers Core lab Pediatric outpatient unit (and virtual in-patient facility) Meeting and teaching space (PH10 stem) Community Site: 178 th St and Fort Washington Ave
8 What are the components of the Irving Institute? Irving Institute Resources: 1. Development of Novel Methodologies Resource 2. Pilot & Collaborative Studies Resource 3. Biomedical Informatics Resource 4. Design & Biostatistics Resource 5. Regulatory Knowledge Support & Ethics Resource 6. Clinical Research Resource 7. Community Engagement Core Resource 8. Translational Technologies & Resources 9. TRANSFORM (educational programs)
9 WHAT DO THE IRVING INSTITUTE RESOURCES PROVIDE?
10 Pilot & Collaborative Studies Resource Provides seed funding for innovative, interdisciplinary research efforts particularly those that bring together new investigative teams Key Components: Pilot Awards: With the CTO, the Irving Institute awards 16 one-year awards of $50,000 each (with departmental matching funds). TIMELINE: Announced annually in late Dec/early Jan for March deadline CaMPR Awards: Provides 4 team-building grants ($15K) and 2 planning grants ($75K) for addressing an important problem at the cellular, individual, and community levels. TIMELINE: Next due date for Phase I is September 2014
11 Pilot & Collaborative Studies Resource Provides seed funding for innovative, interdisciplinary research efforts particularly those that bring together new investigative teams Key Components: Informatics CaMPR Award: One team-building grant ($25K) in collaboration with the Dept of Biomedical Informatics. TIMELINE: Basic Science CaMPR Awards: Two team-building awards with basic scientist and clinical scientist collaborating ($40,000) TIMELINE:
12 CaMPR Planning & Pilot Awards Gravity Neutral Orthotic (GNO) - Design and Evaluation of a device to improve the lives of severely disabled children with Spinal Muscular Atrophy Bioengineering, Rehabilitation Medicine, Neurology Identifying barriers to acute stroke rehabilitation and recovery in a multi-ethnic population Neurology, Rehabilitation Medicine, Sociomedical Sciences An Interdisciplinary Collaboration to Create a Biobank to Enable Personalized Medicine at Columbia University DBMI, Pediatrics, Medicine, Epidemiology, Psychiatry, NYPH Improving Appropriate Use of Antibiotics for URI in Children of Recently Immigrated Latinos Nursing, Pediatrics, Population and Family Medicine
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14 Biomedical Informatics Resource Dual roles: Providing information services to support clinical and translational research; conducting original informatics research on the nature of research processes and how information services can improve their efficiency Key Components: Web Portal: Single entry point for all Irving Institute activities ( CUSP: Columbia University Scientific Profiles. A unique search engine that incorporates information from HR, publication and grants databases that will allow investigators to identify new collaborators (in production) Clinical Data Warehouse/RedX: Permits users to query data on sets of patients providers, departments, etc., for study planning.
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16 Design & Biostatistics Resource Provides a wide range of design, statistical, and analytical support services to assist CUMC faculty with grant applications and publications Key Services: Initial, one-hour consult and up to 5 hours of follow-up support FREE TO CUMC FACULTY Grant preparation, including hypothesis writing, study design, analytic plans, and sample size justification (at least 8 weeks lead time) Manuscript writing (at least 4 weeks lead time) Database development
17 The DBR Consult Hypotheses Design Metrics Power Analysis Writing
18 Clinical Research Resource Provides research space and support to expedite and facilitate the collection of quality data in clinical and translational research Key Components: Inpatient and outpatient space for adult and pediatric studies Highly specialized research nursing services Clinical study coordinators in satellites eg, EDs, ICUs Phlebotomy services
19 Community Engagement Core Resource Organizes and guides investigators within and outside of CUMC who are involved in community based research, in order to enhance research efforts and more effectively communicate with our community partners Key Components: Consultation services Pilot awards for community researchers CCPH = Columbia Community Partnership for Health, at 390 Ft. Washington Ave, featuring: A bilingual health library, health-related internet access for community residents, interview and exam rooms for research, conference rooms for health-related lectures and events, pilot grants for training and research For additional information, please see Dr. Ana Abraído-Lanza in public health (aabraido@columbia.edu).
20 Community Engagement Core Resource Organizes and guides investigators within and outside of CUMC who are involved in community based research, in order to enhance research efforts and more effectively communicate with our community partners Key Components: Symposium Course in CBPR with grant awards at end Connect to CBOs Healthy Heights Portal Recruitment for studies
21 Columbia Community Health Partnership
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24 Translational Technology Resource Biomarkers Core: over 100 assays including Mass Spectrometry Lab with lipidomics and metabolomics Organic Synthesis Laboratory Cancer Center Cores
25 TRANSFORM Educational Resources Provides long-term and short-term training and mentoring opportunities to a wide range of clinical and translational investigators, from pre-docs to junior faculty Key Components: K12 Mentored Career Development Award for Assistant Professors (typically announced in fall for July 1 start) MS in POR: Master of Science in Patient Oriented Research (priority deadline March 1 st 2014 for SCHOLARSHIPS) Short-Term training opportunities (e.g., Reach for the R, CSRI Summer Institute, courses)
26 Feedback The K30 and K12 programs have been key steps in my career building: The formal research training through the K30 program has had great impact on the quality of my research and has contributed to a successful RO1 grant application based on work done for the Master s thesis. The K12 program has given me the protected time needed to launch a clinical research career. Petra Kaufmann, MD, MS Formerly at CUMC, Dept of Neurology Now Associate Director for Clinical Research NINDS, NIH
27 Accessing Educational Opportunities through CTSA and Mailman
28 Training Opportunities LONG-TERM OPTIONS: Master s degree programs at MSPH CTSA/K12 Mentored Career Development Award SHORT-TERM OPTIONS: CSRI: Columbia Summer Research Institute Reach for the First R01 PRIDE Career Development Program for Diverse Faculty
29 Master s Degree Programs For fellows and junior faculty Most relevant programs: MS in Patient Oriented Research (30 pts) MPH (45 pts) or MS (30 pts) in Epidemiology MS in Biostatistics: Clinical Research Methods Track (30 pts) MPH in General Public Health GPH (45 pts) MPH in Effectiveness & Outcomes Research (45 pts) Web Site for Descriptions: Web Site for Applying:
30 CTSA K12 Award For junior faculty (Assistant Professors) only Program offers: Two years of salary support (75% effort; costs borne by department and program) plus funds for tuition, research costs, travel, etc. ($25K/year) Didactic training (MS/POR for those without research Master s) Mentored research project Colloquium on Career Development Assistance with independent grant application Next Deadline: Late fall 2014 Web site:
31 CSRI: Columbia Summer Research Institute Intensive 5-week summer training program Curriculum includes: biostatistics, epidemiology, race and health, decision and cost-effectiveness analysis, grant-writing, comparative effectiveness methods Earn 10 academic pts; can be used towards full degree program Instructors are outstanding Mailman and P&S faculty Participants develop a grant proposal as part of the summer requirements csri@columbia.edu Web Site:
32 Reach for the First R01 Non-credit course, offered twice per year: FALL & SPRING Eligibility: Must be an Early Stage Investigator as per NIH: Must be supported/recommended by a senior faculty member Up to six junior investigators will be selected for this course each term, across all departments. Advantages: Successful applicants will receive 5 free hours of biostatistical consulting, access to other Irving Institute Resources, 2 expert pre-reviews on their R01 applications, and a bi-monthly meeting to ensure structure and timeliness in completing the tasks required to submit a first application. For details, contact Sophia Li Ferry, Administrative Manager for TRANSFORM Educational Programs (ssl2133)
33 How do I access these resources or get more info? To access the CTSA research resources, visit the web site: Fill out the request form on the web site for consultation or more information. To find out more about courses at MSPH, visit the website: Or contact the school at: ph-admit@columbia.edu
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