Career Development Grants- Everything but the Research Plan
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1 Career Development Grants- Everything but the Research Plan Mary-Claire Roghmann, M.D., M.S. Former Career Development Award Recipient Member, NHLBI K23, K24, K25 Study Section AdHoc NIAID K, T32 Study Section
2 Overview What are they? How do you write one? Candidate Career Development Plan Mentoring Plan Institutional Commitment How do you get started?
3 What is a Career Development Grant? Faculty level, individual award Goal: Develop into an independent investigator 75% protected research time Further research training Mentored research experience Limited research $$$ 25% time for clinical service, administrative service and teaching
4 Sources of Career Development Grant K grants NIH Institute-specific CDC AHRQ VA Research and Development Foundations
5 K12 Grants at UMB Faculty level, institutional award Analogous to a T32 Maryland's Organized Research Effort in Women's Health Pat Langenberg (PI) Spring 2015 applications h/bircwh_app.asp Applications are shorter versions of K grant; may ask for interview and/or presentaton
6 K01 K01 vs. K08 vs. K23 Eligibility Any doctoral degree Only certain institutes K08 Clinical doctoral degree Degree leads to a license to see patients If in doubt, ask Program Officer All institutes K23 Clinical doctoral degree Patient-oriented research All institutes
7 What is patient-oriented research? Research conducted with human subjects (or on material of human origin such as tissues, specimens, and cognitive phenomena) for which an investigator directly interacts with human subjects This area of research includes: mechanisms of human disease; therapeutic interventions; clinical trials, and; the development of new technologies.
8 What is not patient-oriented research? Laboratory work on samples from human subjects Health Services Research Outcomes Research Decision Analysis Epidemiological Research Case-control Study Cohort Study Unless you are directly collecting the data from patients
9 Career Development (K) Grant Candidate Overview Career Development Plan Mentor and Mentoring Plan Institutional Support Research Plan Not an R01, a training vehicle that will lead to preliminary data for an R01
10 Candidate s Statement Goal: Provide evidence to demonstrate your promise as a researcher Length: pages Think of this component as your scientific autobiography Education & Training Research Experience Research Accomplishments to date (awards) Commitment to a Research Career Previous collaborations Academic Record
11 Conceptualize as history of your interest in this field When I entered the University of Maryland School of Medicine in August 2000, my goal was to become a family practice physician. But during my second year of medical school, I had a rotation at the VA, where I had my first experience with geriatric patients. To my own surprise, I found that I particularly enjoyed working with this group of patients, many of whom had complex medical problems but also, as a group, had a feisty attitude that helped them cope. In the beginning, I was an engineer.
12 Candidate s Statement: Career Goals and Objectives Short & Long Term Career Goals My long-term goal in seeking this Mentored Patient- Oriented Research Award is to become an independent translational investigator with a career focused on What you ve done towards attaining these goals Need for additional training Training must include new skill; you won t be competitive if K appears to be a repetition of your post-doctoral fellowship Your academic research goal including how attaining this grant will help you reach this goal
13 Career Development Plan I Detail the knowledge, skills, training you need to become an independent investigator Formal coursework (charts, tables) Specific skills and plan to attain these (new tools, collaborations) Plan to work with mentors 2 hours a week gold standard Mentorship and Collaborators Detailed description of what skills you ll learn from each mentoring; how this learning will occur; how often you ll interact, etc. Research Advisory Committee members, how often you ll meet, evaluation metrics
14 Career Development Plan II Training Activities Coursework: course number, title, term, # credits, brief description of content (if needed), competencies Coursework should be completed by end of year 2 Training in technical skills needed for project (lab, clinic) Career Development Timetable Research activities (didactic coursework, technical training, manuscript preparation, preparation of R01 during year 3)
15 Career Development Plan III Your plan to become a knowledgeable, productive scientist Team management training Hiring and supervising staff, managing projects, mentoring, time management Scientific Communication Experience presenting at meetings Scientific Writing Manuscripts Grants
16 How do I choose? Focused Coursework <6 credits <1 year Certificate Degree 12 credits 1-2 years Masters Degree credits 2-3 years Doctoral Degree credits >3 years What s your background? How much prior research training have you had? What skills do you need? How much course work is needed to develop these skills?
17 Focused Coursework Best for those with a prior research degree Base the courses on the knowledge, skills, training you need to become an independent investigator Always include: Lab and Project Management Scientific Communication Oral presentations Papers and Grants
18 Certificate in Clinical Research PREV600 PREV620 PREV616 PREV706 PREV633 Principles of Epidemiology Principles of Biostatistics Introduction to Clinical and Translational Research at UMB Research Informatics : Data Management in Clinical Research Legal and Regulatory Issues in Clinical Research Based on core competencies in Clinical and Translational Research; can substitute courses if taken previously
19 Masters of Science Degree in Thirty-six (36) credits Clinical Research I Two years on a part-time basis Core courses (17-18 credits) in epidemiology (3 credits), biostatistics and data management (10 credits), Developing a clinical research project (2 credits), and legal, ethical, and regulatory issues related to clinical research (2-3 credits)
20 Masters of Science Degree in Clinical Research II Students can concentrate in one of multiple clinical or translational research areas: Patient-oriented research Epidemiology Outcomes/health services research Human genetics Research Ethics All students will be required to do a mentored research project Masters Thesis Research Practicum Other Electives
21 Training in Responsible Conduct of Minimum ½ page Research Do NOT simply state you ll take required course Detail subject matter, format, frequency, duration of instruction Read the instructions! Go the extra mile if you are working in a controversial (or not) area Vulnerable subjects Children, prisoners, employees Stem cells Conflict of interest
22 Mentor & Mentoring Plan I Research qualifications in the area of the project History of publications and support Extent and quality of his/her proposed role in guiding and advising the applicant Quality of Research Plan is a reflection of this process Past history with the mentee is a plus How often are you going to meet, what are you going to do during the meeting
23 Mentor & Mentoring Plan II Previous experience in training researchers Table or list of past trainees Level of training, project, publications, current position, current funding Protection of at least 75% of candidate s time to proposed research
24 Institutional Commitment Strong level of commitment to the candidate s development into an independent investigator Faculty position not contingent on receipt of the award Evidence that the candidate's time has been protected Resources given to the candidate A minimum of 75% of full-time effort will be protected for the program Consistency Details of what the 25% time will consist of
25 Sources of K Grant Information Research Training and Career Development K Kiosk: National Institutes of Health, National Heart, Lung and Blood Institute (NIH/NHLBI) Resources Program Officer (PO) & Study Section Scientific Review Officer (SRO)
26 Sources of VA Career Development Grant Information VA R&D Central Office Website CD grants service-specific VA R&D Service Baltimore VA MC Miriam Smyth, Ph.D. Phone Baltimore VAMC 3A-125
27 Foundations American Heart Association Career/Early-Career-Council-Awards_UCM_322102_Article.jsp American Cancer Society ies/indexofgrants/mentoredtrainingandcareerdevelopmentgrants/ American Diabetes Association March of Dimes (birth defects) Paul B. Beeson Career Development Award (Aging) Call prior grant recipients and administrative contacts
28 More Help Along the Way Mentor(s), Institutional K30 Award Faculty, Current Awardees Coursework and Workshops
29 What if a Career Development Grant is not an option? Startup package Support on a mentor s grant What % effort? Grants to obtain preliminary data for an R01 R03, R21 Institute-specific Be aware of the timeline to awarding of $$ Respond to a RFA in your area of interest Sporadic, one-shot
30 Thoughts on getting started As early as possible, find a research group and do research! Present it. Publish it! Locate a mentor or mentors Word of mouth NIH Reporter (K24 awards) or VA Merit award Agree on a research idea that extends or works off of a mentor s project Talk to your institution Develop your career development plan based on the skills needed for the project and your past experience Find funded grants. Figure out your study section.
31 Career Development Grants Summary Goal of CD grants: Develop into an independent investigator Is this your goal? How do you want to do this? Your background needs to show your commitment to your goals Career development plan needs to be consistent with your goals The grant is yours, but you won t get it without the right mentor That mentor needs to work with you on a research plan and a mentoring plan
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