MCB 300: Microbiology

Transcription

1 Course Web Site: Instructors: Cari Steven C226 CLSL 302 Burrill Hall F: 2:00 3:00pm in B124 CLSL Th: 3:00 3:45pm in 302A Burrill Hall Course Coordinator: Teaching Assistant Renee Alt Kyle Grimm 232A Burrill Hall Office Hour: W: 1:30 to 4:30pm in 101 Burrill Hall Textbook The textbook for this course is Brock: Biology of Microorganisms by Madigan, Martinko, Stahl and Clark, Pearson Education, Inc., 2015 (14th edition). E-book versions (web or downloadable) can be purchased from the publisher ( for less than the price of the hardcover version. A copy of the textbook is also on reserve at the Undergraduate Library and the Learning Center (101 Burrill Hall). Note: Although all material on exams will be covered in lecture, the textbook is strongly recommended reading for enhanced understanding of the course material. Course Policies: All students are assumed to have read and understood the Code of Policies and Regulations Applying to All Students, University of Illinois, and will be expected to act accordingly. The Code is available online at: Disabilities and Religious Observances: Please contact the course coordinator during the first week of classes to make requests for disability accommodations or observation of religious holidays.

2 Wed Jan 18 Lecture 1 Course Introduction and Policies Why study Microbiology? Homework 1 open, due 1/25/17 by 10 AM Fri Jan 20 Lecture 2 What makes a microbe? Historical Perspectives Mon Jan 23 Lecture 3 What makes a microbe? On Being Small Wed Jan 25 Lecture 4 What makes a microbe? Microbial Cell Structure 1 Fri Jan 27 Lecture 5 What makes a microbe? Microbial Cell Structure 2 Mon Jan 30 Lecture 6 iclicker 1 Wed Feb 1 Lecture 7 iclicker 2 Fri Feb 3 Lecture 8 iclicker 3 Mon Feb 6 Lecture 9 iclicker 4 Wed Feb 8 Lecture 10 iclicker 5 What makes a microbe? Microbial Cell Structure 3 Homework 2 open, due 2/6/17 by 10 AM Growth and Motility Bacterial DNA Replication and Cell Division Gene Expression Mechanisms of Genetic Regulation Fri Feb 10 Exam 1 Covers Lectures 2-10 Mon Feb 13 Lecture 11 iclicker 6 Transport Homework 3 open, due 2/20/17 by 10 AM

3 Wed Feb 15 Lecture 12 iclicker 7 Fri Feb 17 Lecture 13 iclicker 8 Mon Feb 20 Lecture 14 iclicker 9 Wed Feb 22 Lecture 15 iclicker 10 Fri Feb 24 Lecture 16 iclicker 11 Mon Feb 27 Lecture 17 iclicker 12 Wed Mar 1 Lecture 18 iclicker 13 Fri Mar 3 Lecture 19 iclicker 14 Mon Mar 6 Lecture 20 iclicker 15 Chemotaxis Metabolic Regulation and Metabolism 1 Metabolism 2 Energy Generation 1 Energy Generation 2 Photosynthesis Homework 4 open, due 3/6/17 by 10 AM Stress responses Quorum Sensing Development Wed Mar 8 Exam 2 Covers Lectures Fri Mar 10 Lecture 21 Establishment of microbial communities I: The Role of Evolution in Establishing Community Structure Drop Deadline Mon Mar 13 Lecture 22 iclicker 16 Wed Mar 15 Lecture 23 iclicker 17 Establishment of microbial communities II: Rapid Change through Horizontal Gene Transfer Homework 5 open, due 3/27/17 by 10 AM Who lives in and around us I: Nature of Microbial Communities, &, Culture Independent Techniques

4 Fri Mar 17 Lecture 24 Who lives in and around us II: Exploring the Human Skin and Vaginal Microbiomes. Mon Mar 20 Spring Break No Class Wed Mar 22 Spring Break No Class Fri Mar 24 Spring Break No Class Mon Mar 27 Lecture 25 Who lives in and around us III: iclicker 18 Wed Mar 29 Lecture 26 iclicker 19 Fri Mar 31 Lecture 27 iclicker 20 Mon Apr 3 Lecture 28 iclicker 21 Wed Apr 5 Lecture 29 iclicker 22 Fri Apr 7 Lecture 30 iclicker 23 Navigating the Human Gut Microbiome. Pathogenic Microbe-Host Interactions-I: Introduction to Infectious Diseases and Microbial Pathogenesis. Homework 6 open, due 4/5/17 by 10am Pathogenic Microbe-Host Interactions-II: Host Barriers to Microbial Interactions. Pathogenic Microbe-Host Interactions-III: Host Innate Defenses to Pathogenic Microbes. Pathogenic Microbe-Host Interactions-IV: Host Adaptive Defenses to Pathogenic Microbes. Pathogenic Microbe-Host Interactions-V: Studying the Virulence of Pathogenic Microbes - Koch's Postulates, Infection Models, & Identifying Virulence Factors. Mon Apr 10 Exam 3 Covers Lectures Wed Apr 12 Lecture 31 iclicker 24 Fri Apr 14 Lecture 32 iclicker 25 Pathogenic Microbe-Host Interactions-VI: Establishing an Infection within the Host - Immune Evasion and Colonization. Pathogenic Microbe-Host Interactions-VII: Invasion, Intracellular Survival, Dissemination, and Transmission. Homework 7 open, due 4/21/17 by 10am Mon Apr 17 Lecture 33 iclicker 26 Wed Apr 19 Lecture 34 iclicker 27 Fri Apr 21 Lecture 35 iclicker 28 Pathogenic Microbe-Host Interactions-VIII: Remodeling the Host into a Suitable Infection Microenvironment the Amazing World of Bacterial Toxins. Pathogenic Microbe-Host Interactions-IX Fantastic Effectors and Where to Find Them. Controlling Bacterial Infections or are we?: The Life and Death Business of Generating Effective Antimicrobials in the Face of Antimicrobial Resistance.

5 Mon Apr 24 Lecture 36 iclicker 29 Going Viral-I: The Amazing Diversity of Viruses; How Form Follows Function. Homework 8 open, due 5/1/17 by 10am Wed Apr 26 Lecture 37 Going Viral-II: iclicker 30 How Viruses cause Disease. Fri Apr 28 Lecture 38 Going Viral-III: iclicker 31 How Viruses of Microbes Shape Ecosystems. Mon May 1 Lecture 39 Eukaryotic Pathogens: Wayward Fungi, Mycoses, and a Hypothesis. Wed May 3 Lecture 40 Vaccines as the Real Game Changer: Next Generation Strategies to Prevent Microbial Diseases in Humans. Thu May 4 Reading Day No Class Friday, May 12 1:30-4:30pm Final Exam Covers Lectures 31-40