MCB 300: Microbiology

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1 Course Web Site: Instructors: Bill Steven B415 CLSL 302 Burrill Hall Office Hours: Office Hours: M: 4:00 5:00pm in B415 CLSL Th: 3:00 3:45pm in 302A Burrill Hall (or by appointment) (or by appointment) Course Coordinator: Teaching Assistant Renee Alt Molly Crowder 232A Burrill Hall Office Hour: Mondays: 12:30pm to 1:30pm Office Hours: (or by appointment) Textbook The textbook for this course is Brock: Biology of Microorganisms by Madigan, Martinko, Stahl and Clark, Pearson Education, Inc., 2015 (15th edition). E-book versions (web or downloadable) can be purchased from the publisher ( for less than the price of the hardcover version. A copy of the textbook is also on reserve at the Undergraduate Library and the Learning Center (101 Burrill Hall). Note: Although all material on exams will be covered in lecture, the textbook is strongly recommended reading for enhanced understanding of the course material. Course Policies: All students are assumed to have read and understood the Code of Policies and Regulations Applying to All Students, University of Illinois, and will be expected to act accordingly. The Code is available online at: Disabilities and Religious Observances: Please contact the course coordinator during the first week of classes to make requests for disability accommodations or observation of religious holidays.

2 Mon Aug 27 Lecture 1 Course Introduction/Careers in Microbiology Wed Aug 29 Lecture 2 The Microbial World Fri Aug 31 Lecture 3 The P Word Homework 1 open, due 9/7/18 by 9 AM Mon Sept 3 No Class Labor Day Wed Sept 5 Lecture 3 The P Word (cont) Fri Sept 7 Lecture 4 On Being Small Mon Sept 10 Lecture 5 iclicker 1 Wed Sept 12 Lecture 6 iclicker 2 Fri Sept 14 Lecture 7 iclicker 3 Mon Sept 17 Lecture 8 iclicker 4 Wed Sept 19 Lecture 9 iclicker 5 Fri Sept 21 Lecture 10 iclicker 6 Microbial Cell Structure Homework 2 open, due 9/17/18 by 9 AM Microbial Cell Structure (cont) Microbial Cell Structure II/Microbial Growth and Replication Microbial Growth and Replication I (cont) Microbial Growth and Replication I (cont) Microbial Physiology I Mon Sept 24 Exam 1 Covers Lectures 2-9 Wed Sept 26 Lecture 11 iclicker 6 Microbial Physiology I/II

3 Fri Sept 28 Lecture 12 iclicker 7 Microbial Physiology II Homework 3 open, due 10/8/18 by 9 AM Mon Oct 1 Lecture 13 iclicker 8 Wed Oct 3 Lecture 14 iclicker 9 Fri Oct 5 Lecture 15 iclicker 10 Photosynthesis I Photosynthesis II Photosynthesis III Mon Oct 8 Lecture 16 iclicker 11 Wed Oct 10 Lecture 17 iclicker 12 Fri Oct 12 Lecture 18 iclicker 13 Life without air/fermentation Homework 4 open, due 10/15/18 by 9 AM Life without air/respiration Methanogenesis and Syntrophy Mon Oct 15 Lecture 19 iclicker 14 Chemolithotrophs Wed Oct 17 Exam 2 Covers Lectures Fri Oct 19 Lecture 21 Establishment of microbial communities I: The Role of Evolution in Establishing Community Structure Drop Deadline Mon Oct 22 Lecture 22 iclicker 16 Establishment of microbial communities II: Rapid Change through Horizontal Gene Transfer Homework 5 open, due 10/29/18 by 9 AM

4 Wed Oct 24 Lecture 23 iclicker 17 Who lives in and around us I: Nature of Microbial Communities, &, Culture Independent Techniques Fri Oct 26 Lecture 24 Who lives in and around us II: Exploring the Human Skin and Vaginal Microbiomes. Mon Oct 29 Lecture 25 iclicker 18 Wed Oct 31 Lecture 26 iclicker 19 Who lives in and around us III: Navigating the Human Gut Microbiome. I: Introduction to Infectious Diseases and Microbial Pathogenesis. Fri Nov 2 Lecture 27 iclicker 20 Mon Nov 5 Lecture 28 iclicker 21 Wed Nov 7 Lecture 29 iclicker 22 Fri Nov 9 Lecture 30 iclicker 23 Homework 6 open, due 11/7/18 by 9am II: Host Barriers to Microbial Interactions. III: Host Innate Defenses to Pathogenic Microbes. IV: Host Adaptive Defenses to Pathogenic Microbes. V: Studying the Virulence of Pathogenic Microbes - Koch's Postulates, Infection Models, & Identifying Virulence Factors. Mon Nov 12 Exam 3 Covers Lectures Wed Nov 14 Lecture 31 iclicker 24 VI: Establishing an Infection within the Host - Immune Evasion and Colonization.

5 Fri Nov 16 Lecture 32 iclicker 25 VII: Invasion, Intracellular Survival, Dissemination, and Transmission. Homework 7 open, due 11/30/18 by 9am Mon Nov 19 Fall Break No Class Wed Nov 21 Fall Break No Class Fri Nov 23 Fall Break No Class Mon Nov 26 Lecture 33 iclicker 26 Wed Nov 28 Lecture 34 iclicker 27 Fri Nov 30 Lecture 35 iclicker 28 Mon Dec 3 Lecture 36 iclicker 29 Wed Dec 5 Lecture 37 iclicker 30 Fri Dec 7 Lecture 38 iclicker 31 VIII: Remodeling the Host into a Suitable Infection Microenvironment the Amazing World of Bacterial Toxins. IX: Fantastic Effectors and Where to Find Them. Controlling Bacterial Infections or are we?: The Life and Death Business of Generating Effective Antimicrobials in the Face of Antimicrobial Resistance. Going Viral-I: The Amazing Diversity of Viruses; How Form Follows Function. Homework 8 open, due 12/10/18 by 9am Going Viral-II: How Viruses cause Disease. Going Viral-III: How Viruses of Microbes Shape Ecosystems. Mon Dec 10 Lecture 39 Eukaryotic Pathogens: Wayward Fungi, Mycoses, and a Hypothesis. Wed Dec 12 Lecture 40 Vaccines as the Real Game Changer: Next Generation Strategies to Prevent Microbial Diseases in Humans.

6 Thu Dec 13 Reading Day No Class Tues, Dec 18 1:30pm- 4:30pm Final Exam Covers Lectures 31-40

GENERAL MICROBIOLOGY (BIOL 021 ISP)

GENERAL MICROBIOLOGY (BIOL 021 ISP) COURSE STRUCTURE AND PURPOSE: General Microbiology is offered for 4- and 5-unit as a 29-day intensive, face-to-face, immersion course organized into 4 learning periods. Each learning period comprises 2